Facilities
The large, modern, well-equipped, laboratory facilities on the medical campus include over 2.65 million square feet of space (25 buildings) dedicated to education and laboratory research. Total research expenditures within the Medical Center are approximately $342.5 million per year, of which $270 million come from the National Institutes of Health. The University of Michigan ranks sixth nationally in total NIH funding.
Research is greatly facilitated by the University of Michigan Biomedical Research Core Facilities (BRCF), which serve as campus-wide resources for developing and providing state-of-the-art biomedical research services. The BRCF ensure that individual investigators have access to new biomedical research services and costly instrumentation. They provide highly trained personnel to carry out technically demanding procedures, thus providing increased quality control and efficiency. The BRCF also sponsor relevant mini-courses and technical symposia. The cost of running the BRCF is subsidized by the University. The Core Facilities include the following:
- Biochemical Nuclear Magnetic Resonance Core
- Biosafety Containment Facility provides a safe environment for the culture and analysis of pathogenic Risk Group II and III viral agents, including HIV-1, HIV-2, HTLV-I, Hepatitis B and many other indigenous human pathogens.
- DNA Sequencing Core Facility
- Flow Cytometry Core Facility
- Hybridoma Core Facility generates somatic-cell hybrids (hybridomas) that produce monoclonal antibodies of desired specificity.
- Microarray Core Faciliities - Several exist on Campus. The Affymetrix and cDNA Micorarray Core Facility run by the U of M Comprehensive Cancer Center is linked here.
- Microscopy and Image Analysis Laboratory provides facilities for light and fluorescence microscopy, confocal microscopy, and scanning and transmission electron microscopy.
- Organogenesis Morphology Core Facility
- Protein Structure Facility provides research services in peptide synthesis, protein analysis and protein mass spectrometry.
- Biomedical Research Store maintains in-house stocks of restriction enzymes, cell culture reagents, and other related enzymes and molecular biology reagents from several vendors.
- Transgenic Animal Model Core Facility
- Vector Core Facility produces state-of-the-art recombinant retroviruses and adenoviruses for use in projects related to recombinant gene expression and gene therapy.
- shRNA Library Core provides Open Biosystem's full human and mouse lentiviral shRNAmir pGIPZ Libraries. Clones and plasmids are available.
- siRNA High Throughput Facility provides high-throughput genome-wide siRNA screening.
- Center for Chemical Genomics performs high throughput small molecule chemical screening to identify small molecules that inhibit or activate enzymes and biological processes of interest.
- Experimental Irradiation Core performs gamma irradiation of cell cultures, tissue specimens, or animals.
The University of Michigan Hospitals, the predominant site for clinical training, are modern, state-of-the-art facilities. There are more than 43,000 inpatient admissions and 1.6 million outpatient visits each year. In addition, the Medical Center has established satellite clinics and a 400-acre satellite campus nearby to provide expanded primary care outpatient services and related educational experiences. Clinical training is also undertaken at area hospitals including the Ann Arbor Veterans Administration Hospital. The Ann Arbor VA Hospital has 145 inpatient beds and 278,000 outpatient visits a year; it also includes 37,000 square feet of research space with an annual budget of $10.6 million dedicated for the use of Medical Center faculty.
The Medical Center also is the recipient of a $55 million Clinical and Translational Science Award (CTSA) from the NIH, which provides resources for clinical and translation research performed in both the inpatient and outpatient settings.
The Taubman Medical Library and the Learning Resource Center are up-to-date, capacious, and comfortable. The University and the Office of Medical Center Information Technology provide computer resources and related services that are reliable, efficient and state-of-the-art.