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Scientific Retreat

Our Annual Scientific Retreat for 2008 was held from August 1 - 3 at the MacMullan Conference Center in Roscommon, MI. Guest speakers included Robert Bartlett, M.D. speaking on "Translational Research: Lessons from Extracorporeal Life Support" The weather was great, we had lots of fun (some of the photos in our Picture Gallery are from this Retreat), and the presentations by fellows in the research phase of their training were enlightening. The research presentations included the following:

FELLOW
MENTOR
TITLE OF PRESENTATION
Omobolaji O. Akala Michael F. Clarke, M.D. Long-term Hematopoietic Reconstitution by Multipotent Progenitors in Mice Deficient of the Tp53 and Ink4a/Arf Loci
Heather M. Ames Theodora S. Ross, M.D., Ph.D. Hip1 and Merkel Cell Carcinoma
Andrea C. Baines David Ginsburg, M.D. Mouse Models Reveal Diverse Roles for the Mammalian Isoforms of COPII
Ferdous Barlaskar Gary D. Hammer, M.D., Ph.D. The Type 1 Insulin-like Growth Factor Receptor as a Novel Therapeutic Target in Adrenocortical Carcinoma
Mark D. Benson Jorge A. Iniguez, Ph.D. The Role of SUMO Modification in the Regulation of Kv1.5, a Major Cardiovascular Potassium Channel
Graham F. Brady Colin Duckett, Ph.D. Identification of CCS as a XIAP-interacting Protein and Target for Ubiquitination
Andrew Bryan Michele Swanson, Ph.D. Applying Recombineering to Study the FliA Regulon of Legionella pneumophila
Christoph C. Carter Kathleen L. Collins, M.D., Ph.D. HIV and hematopoietic progenitor cells: infection, latency and induction
Michelle Debbink Paula Lantz, Ph.D. The Impact of Racial Isolation: Residential Segregation and Preterm Birth in Michigan Cities
Nicholas J. Douville Shuichi Takayama, Ph.D. Impact on Dysfunctional Surfactant Composition on Air-Blood Barrier Integrity
Matthew J. Elrick Andrew P. Lieberman, M.D., Ph.D. The Role of Autophagy in the Neurodegenerative Disorder Niemann-Pick Type C
Jocelyn Farmer David Miller, M.D., Ph.D. Maturation-Dependent Changes in the Neuronal Type I Interferon Pathway
Cole J. Ferguson Miriam H. Meisler, Ph.D. Exploring pale tremor Pathology and a Potential Model of CMT4J
Sean P. Ferris Randal J. Kaufman, Ph.D. Characterizing the in vivo role of UGT1 (UDP-glucose:glycoprotein glucosyltransferase)
Gregory T. Gurda John A. Williams, M.D., Ph.D. Regulator of Calcineurin 1 (Rcan1) Controls Growth Plasticity of Adult Pancreas
Matthew C. Hyman David J. Pinsky, M.D. Regulation of ENTPDase1 (CD39) Expression by Fluid-phase Shear Forces
Stephanie Jo Jay Hess, M.D., Ph.D. The Role of MLL Partner Associated Complex in Leukemia
Michael S. Khodadoust David M. Markovitz, M.D. Control of Melanoma Chemoresistance and Senescence by the Oncoprotein DEK
Mark J. Kiel Sean Morrison, Ph.D. Hematopoietic Stem Cells Do Not Depend on N-cadherin for Their Maintenance
Alana E. Kirby John C. Middlebrooks, Ph.D. Changes in Transmission of Temporal Information in the Auditory Pathway after Deafening and Chronic Stimulation
Andrea K. Knittel Rachel C. Snow, Ph.D. Prison Health and HIV in the Michigan Department of Corrections
Kenneth T. Krill Gary D. Hammer, M.D., Ph.D. Role of micro-RNA in Adrenal Development and Carcinogenesis
Michelle M. Kron Jack Parent, M.D. Seizure-Induced Cellular Abnormalities of Adult-Born Dentate Granule Cells
Alice D. Lam Edward L. Stuenkel, Ph.D. SNARE-Catalyzed Fusion Events are Regulated by Syntaxin1A-Lipid Interactions
Jae Y. Lee Sean Morrison, Ph.D. Inactivation of Senescence Pathways Accelerates Leukemogenesis and Partially Rescues Stem Cell Activity Following Pten Deletion
Brandon C. McKinney Geoffrey G. Murphy, Ph.D. The L-type Voltage-gated Calcium Channel CAV1.3 Mediated Consolidation, but not Extinction, of Contextually-conditioned Fear in Mice
L. Evan Michael Andrzej A. Dlugosz, M.D. Spatial and Temporal Requirements for Hh Signaling in Medulloblastoma Pathogenesis
Karolyn A. Oetjen Nicholas W. Lukacs, Ph.D. Loss of Cellular Inhibitor of Apoptosis 1 (c-IAP1) Impairs Innate Immune Responses to Gram-Negative Bacteria
Daniel C. Peliter David Miller, M.D., Ph.D. The Impact of Neuronal Maturation on Innate Immune System Activation
Matthew W. Pennington David Lubensky, Ph.D. Detailed Analysis of a Model Describing R8 Cell Specification in the Drosophila Eye in 1 Dimension with Random Parameter Searching
Steven T. Philips Theodora S. Ross, M.D., Ph.D. Gleevec Therapy Does Not Diminish the Frequency of Leukemia Transferring Cells in a Novel Mouse Model of Leukemia
Lev Prasov Thomas M. Glaser, M.D., Ph.D. The Role of Math5 and Nr1 in Post-Mitotic Cell Fate Specification in the Mammalian Retina
Scott A. Robertson Martin Myers, M.D., Ph.D. Identification and Analysis of Novel Phosphorylation sites on Jak2
R. Grant Rowe Stephen Weiss, M.D. Epigenetic Regulation of Gene Expression by the Three Dimensional Extracellular Matrix
Hailu Shitaye Kurt Hankenson, Ph.D. The Role of Thrombospondin-2 and Notch Signaling in Mesenchymal Stem Cell Fate Determination
Andrew B. Shreiner Gary Huffnagle, Ph.D. Hypersensitivity Reponse to Aspergillus fumigatus: Immunopathogenesis of Allergic Airway Disease and Pulmonary Arterial Remodeling
Eric R. Tkaczyk Theodore Norris, Ph.D. In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry
Aaron M. Udager Deborah Gumucio, Ph.D. Compartment-specific Gene Expression During Formation of the Epithelial Pyloric Border
Michael Usher Richard Mortensen, M.D., Ph.D. The Mineralocorticoid Receptor Controls Macrophage Polarization During Cardiovascular Injury
Matthew Vasievich David Ginsburg, M.D. Characterization of Mammalian Isoforms of Sec23 in the Early Secretory Pathway
Patrick D. Vigil Harry L.T. Mobley, Ph.D. Identification of Uropathogenic Escherichia coli Genes Expressed During Urinary Tract Infection Using In Vivo Induced Antigen Technology (IVIAT)
Daniel R. Wahl Gary Glick, Ph.D. Bz-423 Improves GVHD-associated Tissue Damage and Mortality by Specifically Targeting Effector T Cells
Steve H. Yang Andrzej A. Dlugosz, M.D. Pathological Reponses to Oncogenic Hedgehog signaling in Skin are Dependent on Canonical Wnt/B-catenin Signaling
William J. Zacharias Deborah Gumucio, Ph.D. Epithelial Hedgehog Signaling Controls Intestinal Mucosal Immunity and IBD Risk

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