Publications
2007
Berent-Spillson A, Russell JW Metabotropic glutamate receptor 3 protects neurons from glucose-induced oxidative injury by increasing intracellular glutathione concentration. Journal of Neurochemistry 101 (2), 342–354, 2007. PMID: 17402968
D'Andrea-Merrins M, Chang L, Lam AD, Ernst SA, Stuenkel EL. Munc18c interaction with syntaxin 4 monomers and SNARE complex intermediates in GLUT4 vesicle trafficking. Journal of Biological Chemistry 282(22):16553-66, 2007. PMID 17412693
2006
Chang B, Khanna H, Hawes N, Jimeno D, He S, Lillo C, Parapuram SK, Cheng H, Scott A, Hurd RE, Sayer JA, Otto EA, Attanasio M, O'Toole JF, Jin G, Shou C, Hildebrandt F, Williams DS, Heckenlively JR, Swaroop A. In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse. Human Molecular Genetics 15:1847-1857,2006. PMID 16632484
Chen X, Walker AK, Strahler JR, Simon ES, Tomanicek-Volk SL, Nelson BB, Hurley MC, Ernst SA, Williams JA, Andrews PC. Organellar proteomics: analysis of pancreatic zymogen granule membranes. Molecular & Cellular Proteomics 5:306-312,2006. PMID 16278343
Crozier SJ, Sans MD, Guo L, D'Alecy LG, Williams JA. Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice. Journal of Physiology 573:775-786,2006. PMID 16613881
Lara-Lemus R, Liu M, Turner MD, Scherer P, Stenbeck G, Iyengar P, Arvan P. Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell. Journal of Cell Science 119:1833-1842,2006. PMID 16608874
Lara-Lemus R, Liu M, Turner MD, Scherer P, Stenbeck G, Iyengar P, Arvan P. Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell. Journal of Cell Science 119(Pt9):1833-1842, 2006. PMID 16608874
Leinninger GM, Backus C, Sastry AM, Yi YB, Wang CW, Feldman EL. Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiology of Disease 23:11-22,2006. PMID 16684605
Siu BB, Saha J, Smoyer WE, Sullivan KA, Brosius III FC. Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by pioic acid treatment. BMC Nephrology 7:6, 2006. PMID 16539708
Straight SW, Pieczynski JN, Whiteman EL, Liu CJ, Margolis B. Mammalian lin-7 stabilizes polarity protein complexes. Journal of Biological Chemistry 281(49):37738-37747, 2006. PMID 17012742
Zhang L, Chenwei L, Mahmood R, van Golen K, Greenson J, Li G, D’Silva NJ, Li X, Burant CF, Logsdon CD, Simeone DM. Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer. Cancer Research 66(2):898-906, 2006. PMID 16424023
2005
Bi Y, Page SL, Williams JA. Rho and Rac promote acinar morphological changes, actin reorganization, and amylase secretion. American Journal of Physiology - Gastrointestinal Liver Physiology 289:G561-G570,2005. PMID 15920016
Bi Y, Williams JA. A role for Rho and Rac in secretagogue-induced amylase release by pancreatic acini. American Journal of Physiology - Cell Physiology 289:C22-C32,2005. PMID 15743890
Fogg VC, Liu CJ, Margolis B. Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells. Journal of Cell Science 118:2859-2869,2005. PMID 15976445
Khanna H, Hurd TW, Lillo C, Shu X, Parapuram SK, He S, Akimoto M, Wright AF, Margolis B, Williams DS, Swaroop A. RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins. Journal of Biological Chemistry 280:33580-33587,2005. PMID 16043481
Kuliawat R, Ramos-Castaneda J, Liu Y, Arvan P. Intracellular trafficking of thyroid peroxidase to the cell surface. Journal of Biological Chemistry 280:27713-27718,2005. PMID 15917231
Latorre IJ, Roh MH, Frese KK, Weiss RS, Margolis B, Javier RT. Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells. Journal of Cell Science 118:4283-4293,2005. PMID 16141229
Margolis B, Borg JP. Apicobasal polarity complexes. Journal of Cell Science 118:5157-5159,2005. PMID 16280548
Ramos-Castaneda J, Park YN, Liu M, Hauser K, Rudolph H, Shull GE, Jonkman MF, Mori K, Ikeda S, Ogawa H, Arvan P. Deficiency of ATP2C1, a Golgi ion pump, induces secretory pathway defects in endoplasmic reticulum (ER)-associated degradation and sensitivity to ER stress. Journal of Biological Chemistry 280:9467-9473,2005. PMID 15623514
2004
Cowell RM, Russell JW. Nitrosative injury and antioxidant therapy in the management of diabetic neuropathy. Journal of Investigative Medicine 52:33-44,2004. PMID 14989368
Hirsch JC, Borton AR, Albayya FP, Russell MW, Ohye RG, Metzger JM. Comparative analysis of parvalbumin and SERCA2a cardiac myocyte gene transfer in a large animal model of diastolic dysfunction. Am J Physiol Heart Circ Physiol 286:H2314-21,2004. PMID 15148059
Kubisch C, Dimagno MJ, Tietz AB, Welsh MJ, Ernst SA, Brandt-Nedelev B, Diebold J, Wagner AC, Goke B, Williams JA, Schafer C. Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology 127:275-86,2004. PMID 15236192
Leinninger GM, Backus C, Uhler MD, Lentz SI, Feldman EL. Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons. FASEB Journal 18:1544-1546,2004. PMID 15319368
Li W, Guan KL. The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak. J Biol Chem 279:32824-31,2004. PMID 15169762
Liu J, Ernst SA, Gladycheva SE, Lee YY, Lentz SI, Ho CS, Li Q, Stuenkel EL. Fluorescence resonance energy transfer reports properties of syntaxin1a interaction with Munc18-1 in vivo. Journal of Biological Chemistry 279:55924-55936,2004. PMID 15489225
Straight SW, Shin K, Fogg VC, Fan S, Liu CJ, Roh M, Margolis B. Loss of PALS1 expression leads to tight junction and polarity defects. Mol Biol Cell 15:1981-90,2004. PMID 14718565
Vincent AM, Olzmann JA, Brownlee M, Sivitz WI, Russell JW. Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death. Diabetes 53:726-34,2004. PMID 14988258
Wang Q, Hurd TW, Margolis B. Tight junction protein Par6 intercts with an evolutionarily conserved region in the amino terminus of PALS1/stardust. Journal of Biological Chemistry 279(29):30715-30721. 2004. PMID 15140881
Wang X, Chen L, Maures TJ, Herrington J, Carter-Su C. SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells. Journal of Biological Chemistry 279:133-41,2004. PMID 14565960
2003-2002
Chen X, Ernst SA, Williams JA. Dominant negative Rab3D mutants reduce GTP-bound endogenous Rab3D in pancreatic acini. J Biol Chem 278:50053-60,2003. PMID 14522985
Fernandes R, Suzuki K, Kumagai AK. Inner blood-retinal barrier GLUT1 in long-term diabetic rats: an immunogold electron microscopic study. Investigative Ophthalmology & Visual Science 44:3150-3154,2003. PMID 12824265
Le Page SL, Bi Y, Williams JA. CCK-A receptor activates RhoA through G alpha 12/13 in NIH3T3 cells. American Journal of Physiology - Cell Physiology 285:C1197-C1206,2003. PMID 12853286
Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB Journal 16:1738-1748,2002. PMID 12409316
Treutelaar MK, Skidmore JM, Dias-Leme CL, Hara M, Zhang L, Simeone D, Martin DM, Burant CF. Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet. Diabetes 52:2503-2512,2003. PMID 14514633
