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BioMedical Division Members

Steven F. Abcouwer, PhD Diabetic retinopathy; Neurodegeneration; Microglia
David A. Antonetti, PhD Diabetic retinopathy, blood-retinal barrier, tight junctions
Peter Arvan MD, PhD Beta cell survival, insulin synthesis, protein folding
Barbara Atshaves, PhD Lipid metabolism, confocal microscopy, obesity
Ruma Banerjee, PhD Sulfer metabolism, redox biochemistry, glutathione
Kate F. Barald PhD Stem cells (embryonic and adult), hormonal effects on neurogenesis and regeneration, neuropathies
Ernesto Bernal-Mizrachi, MD Beta cells biology' Islets, Pancreas development
Markus Bitzer, MD Renal injury, microrna, TGF-beta
Daniel A. Bochar PhD Transcription, chromatin, remodeling
Peter F. Bodary, PhD Exercise, Inflammation, Insulin Resistance
Michael L. Boehnke PhD Statistics, genetics, type 2 diabetes
Steven Britton MD Metabolism, exercise, animal models
Frank C. Brosius III, MD Glucose transport, diabetic nephropathy, vascular biology
Charles Burant, MD, PhD Metabolomics, Beta-cell Biology, Systems Biology
Julia V. Busik, PhD Microvascular complications, retinopathy, dyslipidemia
Gregory Cartee PhD Exercise physiology, glucose transport, insulin signaling
Christin Carter-Su PhD GH receptors and actions, JAK/Stat signaling, tyrosine kinase signaling pathways
Annette M. Chang MD Insulin secretion, exercise, aging, beta-cell mass
Munmun Chattopadhyay, PhD Diabetic neuropathy; pain; gene therapy
Eugene Chen, MD PhDPPARgamma, diabetic drug development, Cadiovascular complications associated with diabetes
Tae-Hwa Chun MD, PhD Extracellular matrix, matrix metalloproteinase, obesity
Mario Delmar, MD, PhD Cardiomyopathies, heart disease, intercellular communication
Peter Dempsey PhD Mouse models of beta cell function, survival and regeneration, growth factor signaling, disintegrin-metalloproteases (ADAMs)
Robert J. Denver PhD Neuroendocrinology, thyroid, adrenal
Matthew DiMagno MD Acute pancreatitis, chronic pancreatitis, pancreatic secretion
Zora Djuric PhD Obesity prevention, dietary intervention, biomarkers
Cunming Duan PhD Hormonal control of growth, IGF, hypoxia
Vicki L. Ellingrod PharmD Schizophrenia, diabetes, folate
Stephen A. Ernst PhD Immunocytochemistry, mechanisms involved in pancreatic acinar exocytosis, SNARE protein interactions
Eva L. Feldman MD, PhD Diabetic neuropathy, insulin-like growth factors, neuromuscular diseases
Diane C. Fingar, PhD Insulin signaling, mammalian target of rapamycin, cell growth and proliferation
David J. Fink, MD Peripheral neuropathy, Pain, Gene therapy
Thomas W. Gardner, MD Diabetic retinopathy; Insulin receptor signaling; Retinal cell death
Puneet Garg, MD Molecular biology of Glomerular Slit Diaphragm, Vascular calcification in end stage renal disease, Hypertension
Margaret Gnegy PhD Protein kinase C-beta, dopamine transporter, dopamine neuron

James G. Granneman, PhD

Adipose tissue, lipolysis, diabetes

Deborah L. Gumucio PhD Hedgehog signaling, intestinal development, absorptive epithelium
Gary D. Hammer MD, PhD Glucocorticoids and nuclear receptors, adrenal gland development, dysregulated growth of adrenocortical stem/progenitor cells in development and adrenocortical carcinoma
John R. Heckenlively, MD Autoimmune retinal diseases, diabetic edema, cystoid macular edema
Todd J Herron, PhD Cardiac myocytes, calcium, myofilaments
Friedhelm Hildebrandt, MD Gene identification in ciliopathies, cystic kidney disease, Bardet-Biedl syndrome, Alstrom syndrome

Jennifer W. Hill, PhD

Hypothalamus, energy homeostasis, fertility

Israel Hodish, MD, PhD Beta-cell biology, Insulin therapy, Transgenic mice
Lawrence B. Holzman MD Cell signaling, podocyte, kidney
Jeffrey F. Horowitz PhD Obesity, Exercise, Metabolism
Patrick Hu MD, PhD Insulin signaling, FoxO transcription factors, C. elegans
H. David Humes MD Bioartificial pancreas
Jorge A. Iniguez-Lluhi PhD Transcriptional regulation, steroid hormone receptors, post-translational modification by Small Ubiquitin-like Modifier i.e. SUMO proteins
Mayumi Inoue MD, PhD Insulin signaling, exocyst complex, vesicle trafficking
Lori L. Isom PhD Sodium channel, cell adhesion, neuropathic pain
Wenjun Ju, PhD non-invasive biomarker identification, pathomechanism study of biomarkers
Alon Kahana, MD, PhD Epithelial-mesenchymal transition, Intercellular signaling processes, Neural crest biology
Randal J. Kaufman PhD Protein misfolding, unfolded protein response, endoplasmic reticulum stress
Alla Karnovsky, PhD Systems Biology Bioinformatics, Metabolomics
Catherine E. Keegan, MD, PhD Mouse genetics, Caudal regression, Congenital malformations
Robert T. Kennedy, PhD Insulin secretion, metabolomics, microfluidics
Tom K. W. Kerppola PhD Transcription regulation and chromatin architecture, molecular interactions, live cell imaging
Edith C Kieffer, MPH, PhD Diabetes, Pregnancy, Disparities
Bhumsoo Kim PhD Alzheimer`s Disease, cell signaling, neuroscience
Lauren G. Koch PhD Animal models, aerobic exercise, complex disease
Ronald J. Koenig MD, PhD PAX8-PPARgamma fusion protein, thyroid cancer, thyroid hormone
Matthias Kretzler MD Systems biology, diabetic nephropathy, molecular diagnostics
Roland Kwok PhD Cancer, acetylation, phosphorylation

Beata Lecka-Czernik, PhD

Antidiabetic therapies; bone marrow adipocytes; bone metabolic diseases

Menq-Jer Lee, PhD Sphingolipid, GPCR, Inflammation
Todd Leff, PhD Diabetes, gene expression, nuclear receptor
Stephen I. Lentz PhD Cell imaging, microscopy, diabetic complications
Jiandie Lin PhD Mitochondrial, transcription, lipid
David B. Lombard, MD, PhD Sirtuins; mitochondria; calorie restriction
Malcolm J. Low, MD, PhD Hypothalamic control of energy homeostasis; Neuropeptide gene expression; Neural circuits underlying food reward
Carey N. Lumeng MD, PhD Obesity, inflammation, macrophage, insulin resistance, adipose tissue
Peter X. Ma PhD Biomaterials, regeneration, controlled release
Ormond A. MacDougald PhD Adipogenesis, obesity, metabolism
Benjamin L. Margolis MD Kidney, polarity, cilia
Laura R. McCabe, PhD Type 1 diabetes induced osteoporosis; Osmoadaptation/osmotic stress; Diabetes induced bone marrow changes/adiposity
Marcia F. McInerney, PhD Innate and adaptive immunity in diabetes; inflammation and cytokines in diabetes; mechanisms of cell movement
K. M. Jairam Menon, PhD G protein coupled receptors, steroids, reproductive hormones
Ram Menon, MD Growth hormone - IGF1 axis, Pediatric endocrinology, Clinical diabetes mellitus
Thomas Morrow PhD Animal models of Type 1 diabetes, supraspinal consequences of diabetes mellitus, pain in diabetes mellitus
Richard M. Mortensen MD, PhD Obesity, cardiovascular disease, immune function
Henry Mosberg, MD, PhD Medicinal chemistry, peptides, receptors
Geoffrey G Murphy PhD Learning/memory, aging, ion Channels
David C. Musch PhD Clinical trial design and methods, epidemiology, quality of life assessment
Martin G. Myers, Jr. MD, PhD Leptin, hypothalamus, energy balance
Sonia M. Najjar, PhD Diabetes and endocrine research
Richard R. Neubig MD, PhD G protein, obesity, insulin sensitivity
David P. Olson, MD, PhD Obesity, hypothalamus, diabetes
Gilbert S. Omenn MD, PhD Bioinformatics, proteomics, cancer prevention
Yoichi Osawa, PhD Nitric oxide
Vasantha Padmanabhan PhD Infertility, polycystic ovarian syndrome, ovary
Sandeep V. Pandit PhD Arrhythmia, cardiac electrophysiology

Narayanan Parameswaran, PhD

Inflammation; cell signaling; toll-like receptors

Joshua J. Park, PhD

Obesity; neuropeptides; hypothalamus

Subramaniam Pennathur MD Oxidative stress, mass spectrometry, proteomics, systems biology, diabetic complications
Sem H. Phan MD, PhD Tissue injury, repair/remodeling/fibrosis, inflammation
Massimo Pietropaolo, MD Autoimmune pathogenesis of Type 1 diabetes, Biomarkers of auutoimmune diabetes, Genetics of Type 1 diabetes
Scott Pletcher, PhD Drosophila melanogaster; diet; obesity; aging
Rodica Pop-Busui Type 1 and type 2 diabetes; diabetes complications, diabetic neuropathy
Donald G. Puro MD, PhD Diabetic retinopathy, cell physiology
Malini Raghavan, PhD autoimmunity, antigen presentation, endoplasmic reticulum (ER) stress)
Gavin E. Reid, PhD Mass spectrometry, proteomics, lipidomics
Diane M. Robins PhD Androgen receptor, liver gene regulation, sex-specific gene expression
Liangyou Rui PhD Diabetes, obesity, leptin and insulin signaling
Alan R. Saltiel, PhD Insulin action; glucose transport; obesity
Linda C. Samuelson PhD Gastric acid secretion, parietal cell biology, gastric cancer, intestinal differentiation
Edwin R. Sanchez, PhD Diabetes and endocrine research
M. Dolors Sans Gili, PhD Exocrine pancreas, physiology, protein synthesis
Leslie S. Satin PhD Pancreatic islets and islet beta cells, insulin secretion oscillations
Jessica Schwartz PhD Growth hormone action, regulation of gene transcription, signal transduction
Audrey F. Seasholtz PhD Stress biology and corticosteroid receptors, neuroendocrinology of stress, corticotropin-releasing hormone receptors and binding protein
Yatrik M. Shah, PhD Hypoxia; Steatosis; Fibrosis
Assia Shisheva, PhD Mouse models of insulin resistance, Insulin responsiveness in target cells and tissues, Mouse models for metabolic syndrome
Roni M. Shtein, MD In vivo cornea confocal microscopy
Yolanda R. Smith MD Menopause, cognition, estrogen, polycystic ovary syndrome
MaryFran R. Sowers PhD Epidemiology, neurological decline with aging, obesity and its impact on carbohydrate metabolism
Edward L. Stuenkel PhD Beta cell, insulin secretion, exocytosis
George W. Taylor DMD, DrPH Epidemiology, periodontal disease, clinical research
John J. G. Tesmer, PhD Structural studies of heterotrimeric G protein signaling, Macromolecular crystallography, Molecular pharmacology
Robert C. Thompson PhD MicroRNA, stress, feeding
Raymond C. Trievel PhD Chromatin modification, transcriptional regulation, enzyme structure and function
Cynthia Tsui, MD, PhD Diabetic nephropathy, Podocyte biology, Growth factor signaling
Michael D. Uhler PhD Protein phosphorylation, cyclic nucleotides, neuronal function
Anjel Vahratian PhD, MPH Obesity, lipid metabolism, women
Anne B. Vojtek PhD Signaling, cell growth, neural differentiation
Lois S. Weisman, PhD Diabetes; phosphatidylinositol 3,5 bis phosphate; endosomes
Stephen J. Weiss MD Adipocytes, adipose tissue, extracellular matrix
Margaret V. Westfall PhD Sarcomere, signaling, heart failure
John A. Williams MD, PhD Exocrine pancreas, diabetes, cell signaling
Zhaohui Xu PhD Structural biology, unfolded protein response, membrane trafficking
Zhengping Yi, PhD Insulin resistance and type 2 diabetes, Mass spectrometry and proteomics, Signal transduction, Protein phosphorylation, Protein-protein interaction
Lei Yin, MD, PhD Circadian rhythm; metabolism, ubiquitination
Xiaochun Yu, MD, PhD Epigenetics, chromatin remodeling, gene transcription
Kezhong Zhang, PhD Lipid metabolism; ER stress, non-alcoholic fatty liver disease