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Basic Research

The University of Michigan Lupus Program has a strong program in basic science research. Areas of research include:

  1. Identifying genetic and epigenetic abnormalities in lupus patients that predispose them to the disease.

  2. T cell abnormalities in lupus.

  3. Abnormal cell death and the development of lupus.

  4. Abnormalities in the Interactions of different cells of the immune system that might predispose lupus patients to the disease.

  5. Mechanisms by which lupus patients develop accelerated heart disease.

  6. Mechanisms of kidney damage in lupus.

  7. Role of dendritic cells and neutrophils in lupus.

  8. Abnormal signal transduction in lupus cells.

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