Venkateshwar Keshamouni, Ph.D.

Research Investigator

 

 

Education and Training:  M.Sc (Biochemsitry): 1989, Osmania University, Hyderabad, India.; Ph.D (Photobiology and signal transduction): 1996, University of Hyderabad, Hyderabad, India.

Post doctoral Training: Department of Biology, Indiana University, Bloomington, Indiana., Department of Pathology, Wayne State University, Detroit, MI.

Research Interests: Growth factor receptors and nuclear hormone receptor signaling in lung tumorogenesis, Epithelial to mesenchymal transition and interactions in lung carcinogenesis.

 

 

 

·        Reddy KB, Keshamouni VG, Chen YQ.  The level of tyrosine kinase activity regulates the expression of p21/WAF1 in cancer cells.  Int J Oncology 1999;15:301-306.

·        Krueger J, Keshamouni VG, Atanaskova N, Reddy KB.  Temporal and quantitative regulation of MAP kinase activation modulates cell motility and invasion. Oncogene 2001; 20:4209-4218.

·        Atanaskova N, Keshamouni VG, Krueger JS, Schwartz JA, Miller F, Reddy KB.  MAP kinase/estrogen cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer Tamoxifen resistance. Oncogene 2002;21:4000-4008.

·        Keshamouni VG, Mattingly RR, Reddy KB.  Mechanism of 17-b-Estradiol-induced Erk1/2 activation in breast cancer cells: A role for HER2 and PKC-d. J Biol Chem 2002;277:22558-22565.

·        Keshamouni VG, Reddy RC, Arenberg DA, Joel B, Thannickal VJ, Kalemkerian GP, Standiford TJ.Peroxisome Proliferator Activated Receptor-g  Activation Inhibits Tumor Progression in Non-

small Cell Lung Cancer. Oncogene 2003 (In press)

·        Reddy RC, Keshamouni VG, jaigirdhar SH, Zeng X, Leff T, Thannickal VJ and Standiford TS. Deactivation of Murine Alveolar Macrophages by Peroxisome Proliferator-activated Receptor-g Ligands. Am J physiol-Lung Cell Mol Physiol 2003: (In press).

 

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