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Milagros D. Samaniego-Picota, MD, FACP, FASN

Research Summary:

Antibody-mediated rejection, management of highly sensitized and high risk kidney transplant recipients, desensitization protocols and ABO incompatible transplantation.

Link to PubMed Citations

Selected Publications:

Huang E, Samaniego M, McCune T, Melancon JK, Montgomery RA, Ugarte R, Kraus E, Womer K, Germino G, Rabb H, and Watnick T.: DNA Testing To Enhance Safety For Live Kidney Donors At Risk For Autosomal Dominant Polycystic Kidney Disease. Am J Transplant (submitted).

Chan MR, Thomas CP, Torrealba JR, Djamali A, Fernandez LA, Nishimura C, Smith RJH, Samaniego M. Recurrent Atypical Hemolytic Uremic Syndrome Associated with Factor I Mutation in a Living Related Renal Transplant Recipient. Am J Kidney Dis (submitted).

Pascual J, Pirsch JD, Odorico JS, Torrealba JR, Djamali A, Becker YT, Voss B, Leverson GE, Knechtle SJ, Sollinger HW, Samaniego M: Alemtuzumab Does Not Prevent Antibody-Mediated Rejection After Simultaneous Kidney-Pancreas Transplantation. Transplantation (submitted).

Friedewald J, Torrealba JR, Samaniego M: Chronic Antibody-Mediated Rejection: Role of Alloantibodies in Chronic Kidney Graft Injury and Fibrogenesis. Nat Clin Pract Nephrol (submitted).

Singh N, Pirsch JD, Samaniego M: Antibody-Mediated Rejection: Treatment Alternatives And Outcomes. Transplantation Reviews (submitted).

Conley E, Muth B, Samaniego M, Lotfi M, Voss B, Armbrust M, Pirsch J, Djamali A: Bisphosphonates and bone fractures in long-term kidney transplant recipients. Transplantation 2008 (In Press).

Pascual J, Samaniego MD, Torrealba JR, Odorico JS, Djamali A, Becker YT, Voss B, Leverson GE, Knechtle S, Sollinger H, Pirsch JD: Antibody-mediated rejection of the kidney after simultaneous pancreas-kidney transplantation. J Am Soc Nephrol 2008 Jan 30; [Epub ahead of print].

Kukla A, Adulla M, Pascual J, Samaniego M, Nanovic L, Becker BN, Djamali A: CKD stage-to-stage progression in native and transplant kidney disease. Nephrol Dial and Transplant 2008 Feb; 23 (2): 693-700.

Smavatkul C, Pascual J, Desai AG, Samaniego M, Becker BN, A Djamali: Disease progression and outcomes in type 1 diabetic kidney transplant recipients based on posttransplant CKD staging. Am J Kidney Dis 2007 Oct; 50 (4): 631-40.

Pascual J, Djamali A, Muth B, Hofmann RM, Samaniego M, Becker B: New Considerations for Chronic Kidney Allograft Injury. Trends in Transplant 2007; 1:95-103.

Samaniego M, Mezrich J, Torrealba J, Lorentzen D, Schadde E, Djamali A, Zachariah M, Sollinger H, Pirsch J: C4d Positive Acute Antibody Mediated Rejection Due to Anti-HLA-DP Antibody: A Tale Of One Patient And Review Of The University of Wisconsin Experience. Clin Transpl 2007.

Pascual J, Mezrich J, Djamali A, Leverson G, Chin LT, Torrealba J, Bloom D, Voss B, Becker BN, Knechtle S, Sollinger H, Pirsch J, Samaniego M: Alemtuzumab induction and recurrence of glomerular disease after kidney transplantation. Transplantation 2007 Jun 15; 83 (11):1429-1434.

Pascual J, Torrealba J, Myers J, Tome S, Samaniego M, Musat A, Djamali A: Collapsing focal segmental glomerulosclerosis in a liver transplant recipient on alendronate. Osteoporosis Int 2007 April 3 [Epub ahead of print].

Djamali A, Sadowski EA, Muehrer RJ, Reese S, Smavatkul C, Vidyasagar A, Fain SB, Lipscomb RC, Hullett DH, Samaniego-Picota M, Grist TM, Becker BN.: BOLD-MRI assessment of Intrarenal Oxygenation and Oxidative Stress in Patients with Chronic Kidney Allograft Dysfunction. Am J Physiol Renal Physiol 2007 Feb; 292 (2): F513-22.

Djamali A, Samaniego M, Muth B, Muehrer R, Hofmann RM, Pirsch J, Howard A, Mourad G, Becker BN: Medical care of kidney transplant recipients after the first posttransplant year. Clin J Am Soc Nephrol 1:623-640, 2006.

Samaniego-Picota M, Becker BN, Djamali A: Maintenance immunosuppression in kidney transplant recipients after the first year post-transplant: current concepts. Nat Clin Pract Nephrol 2006 Dec; 2 (12):688-99.

Djamali A, Sadowski EA, Samaniego-Picota M, Fain SB, Muehrer RJ, Alford SK, Hofmann RM, Grist TM, Becker BN: Non-invasive assessment of early kidney allograft dysfunction by BOLD-MRI. Transplantation 2006 Sep 15; 82 (5):621-8.

Becker YT, Samaniego-Picota M, Sollinger HW: The emerging role of rituximab in organ transplantation. Transpl Int 2006 Aug; 19(8):621-8 .

Melamed ML, Lim K, Jaar BG, Atta MG, Molmenti E and Samaniego MD: Percutaneous Mechanical Thrombectomy for Renal Vein Thrombosis Following Kidney Transplantation. Am J Transplant 2005 Mar;5 (3):621-6.

Baldwin WM, Armstrong LP, Samaniego-Picota M, Rahimi S, Kasper EK, Conte JV, Rodriguez RE, Hruban RH: Anti-thymocyte globulin is associated with complement deposition in early cardiac transplant biopsies. Hum Immunol 2004 Nov;65(11):1273-80.

King KS, Warren DS, Samaniego-Picota M, Campbell-Lee S, Montgomery RA, Baldwin WM, III: Antibody, Complement and Accommodation in ABO-Incompatible Transplants. Curr Opin Immunol 2004 Oct;16(5):545-9.

Sonnenday CJ, Warren DS, Samaniego M, Haas M, King KE, and Montgomery RA: Plasmapheresis, CMV hyperimmune globulin, and anti-CD20 allow ABO-incompatible renal transplantation without splenectomy. Am J Transplant 2004 Aug;4(8):1315-22.

Wu J, Jaar BG, Briggs WA, Choi MJ, Kraus ES, Racusen LC, Atta MG, and Samaniego MD: High dose mycophenolate mofetil in treating recurrent/de-novo disease in the Allograft: a case series. Nephron Clin Pract 2004;98(3):c61-6.

Shepherd J, Subramanian A, Montgomery RA, Samaniego MD, Gong G, Bergmann A, Blythe D and Dropulic L. West Nile Virus Encephalitis in a Kidney Transplant Recipient. Am J Transplant 2004 May;4(5):830-3.


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