Dr. Patel is working in the laboratory of Dr. Greg Dressler (Pathology) where he has focused on transcriptional mechanisms of kidney development.
Link to PubMed Citations
Kim D, Patel SR, Xiao H, Dressler GR. The role of PTIP in maintaining embryonic stem cell pluripotency. Stem Cells. 2009 Jul;27(7):1516-23.
Fang M, Ren H, Liu J, Cadigan KM, Patel SR, Dressler GR. Drosophila ptip is essential for anterior/posterior patterning in development and interacts with the PcG and trxG pathways. Development. 2009 Jun;136(11):1929-38.
Patel SR, Kim D, Levitan I, Dressler GR. The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex. Dev Cell. 2007 Oct;13(4):580-92.
Clarke JC, Patel SR, Raymond RM Jr, Andrew S, Robinson BG, Dressler GR, Brophy PD. Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage. Hum Mol Genet. 2006 Dec 1;15(23):3420-8. Epub 2006 Oct 17.
Lin J, Patel SR, Wang M, Dressler GR. The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia. Mol Cell Biol. 2006 Jun;26(12):4577-85.
Patel SR, Dressler GR. BMP7 signaling in renal development and disease. Trends Mol Med. 2005 Nov;11(11):512-8. Epub 2005 Oct 10. Review.
Lin J, Patel SR, Cheng X, Cho EA, Levitan I, Ullenbruch M, Phan SH, Park JM, Dressler GR. Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat Med. 2005 Apr;11(4):387-93. Epub 2005 Mar 27.
Patel SR, Dressler GR. Expression of Pax2 in the intermediate mesoderm is regulated by YY1. Dev Biol. 2004 Mar 15;267(2):505-16.