Research Summary:

Dr. Ojo has extensive experience in the development and management of multicenter clinical trials. His overall research interests include hypertension, ESRD, and access to kidney transplantation and allograft survival in minority patients with ESRD. His current specific research interests include identifying the risk factors for accelerated decline in renal function in patients with chronic renal insufficiency and evaluating the incidence and risk factors for cardiovascular disease in this population. Dr. Ojo also participates in a multicenter, NIH-sponsored clinical trial, the African American Study of Kidney Disease (AASK).

Link to PubMed Citations

Selected Publications:

Epidemiology of Chronic Kidney Disease. In: Primer on Kidney Disease, Arthur Greenberg, Ed. Academic Press, 2005.

RM Merion, VB Ashby, RA Wolfe, TE Hulbert-Shearon, RA Metzger, AO Ojo, PJ Held, FK Port. Mortality risk in recipients of expanded and non-expanded criteria deceased donor kidney transplants compared with dialysis patients on the waiting list. JAMA 2005 Dec 7;294(21):2726-33.

Ojo AO, Pietroski RE , O’Connor K, McGowan JJ, Dickinson DM. Quantifying organ donation rates by donation service area. Am J Transplant 4(pt2):958-966, 2005.

Phillips RA, Faulkner M, Gassman J, Jaen L, Kusek JW, Norris K, Ojo A. Recruitment of African Americans with chronic renal insufficiency into a multicenter clinical trial: the african american study of kidney disease and hypertension. J Clin Hypertens (Greenwich). 2004 Aug;6(8):430-6.

Ojo AO, Heinrichs D, Emond JC, McGowan JJ, Guidinger MK, Delmonico FL, Metzger RA. Organ donation and utilization in the USA . Am J Transplant. 2004;4 Suppl 9:27-37.

Bustami RT, Ojo AO, Wolfe RA, Merion RM, Bennett WM, McDiarmid SV, Leichtman AB, Held PJ, Port FK. Immunosuppression and the risk of post-transplant malignancy among cadaveric first kidney transplant recipients. Am J Transplant 4:87-93, 2004.

Lopes AA, James SA, Port FK, Ojo AO, Agodoa LY, Jamerson KA. Meeting the challenge to improve the treatment of hypertension in blacks. J Clin Hypertens (Greenwich). 2003 Nov-Dec;5(6):393-401. Review.

Bustami RT, Ojo AO, Wolfe RA, Merion RM, Bennett WM, McDiarmid SV, Leichtman AB, Held PJ, Port FK. Immunosuppression and the risk of post-transplant malignancy among cadaveric first kidney transplant recipients. Am J Transplant. 2004 Jan;4(1):87-93.

Ojo AO, Held PJ, Wolfe RA, Merion RM, Leichtman AB, Young EW, Guidinger M, Christensen L, Port FK; Scientific Registry of Transplant Recipients. Trends in cadaveric organ donation in the United States : 1990-1999. Clin Transpl. 2002;105-9.

Ojo AO, Held PJ, Port FK, Wolfe RA, Leichtman AB, Young EW, Arndorfer J, Christensen L, Merion RM. Chronic renal failure after transplantation of a nonrenal organ. N Engl J Med. 2003 Sep 4;349(10):931-40.

Feldman HI, Appel LJ, Chertow GM, Cifelli D, Cizman B, Daugirdas J, Fink JC, Franklin-Becker ED, Go AS, Hamm LL, He J, Hostetter T, Hsu CY, Jamerson K, Joffe M, Kusek JW, Landis JR, Lash JP, Miller ER, Mohler ER 3rd, Muntner P, Ojo AO, Rahman M, Townsend RR, Wright JT; Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and Methods. J Am Soc Nephrol. 2003 Jul;14(7 Suppl 2):S148-53.

Kayler LK, Rasmussen CS, Dykstra DM, Ojo AO, Port FK, Wolfe RA, Merion RM. Gender imbalance and outcomes in living donor renal transplantation in the United States . Am J Transplant. 2003 Apr;3(4):452-8.

Nathan HM, Conrad SL, Held PJ, McCullough KP, Pietroski RE, Siminoff LA, Ojo AO. Organ donation in the United States . Am J Transplant. 2003;3 Suppl 4:29-40.

Kayler LK, Merion RM, Rudich SM, Punch JD, Magee JC, Maraschio MA, Leichtman AB, Cibrik DM, Ojo AO, Campbell DA Jr, Arenas JD. Evaluation of pancreatic allograft dysfunction by laparoscopic biopsy. Transplantation. 2002 Nov 15;74(9):1287-9.

Obrador GT, Ojo A, Thadhani R. End-stage renal disease in patients with Fabry disease. J Am Soc Nephrol. 2002 Jun;13 Suppl 2:S144-6.

Meier-Kriesche HU, Cibrik DM, Ojo AO, Hanson JA, Magee JC, Rudich SM, Leichtman AB, Kaplan B. Interaction between donor and recipient age in determining the risk of chronic renal allograft failure. J Am Geriatr Soc. 2002 Jan;50(1):14-7.

Lewis J, Agodoa L, Cheek D, Greene T, Middleton J, O'Connor D, Ojo A, Phillips R, Sika M, Wright J Jr. African-American Study of Hypertension and Kidney Disease. Comparison of cross-sectional renal function measurements in African Americans with hypertensive nephrosclerosis and of primary formulas to estimate glomerular filtration rate. Am J of Kidney Dis 38(4):744-753, 2001.

Dhingra RK, Sprague S, Ojo AO, Leavey SF. Post-transplant bone disease: a case illustrating dramatic improvements in bone density with vitamin d replacement therapy. Transplantation71:1856-9, 2001.

Sung RS, Althoen M, Howell TA, Ojo AO, Merion RM. Excess risk of renal allograft loss associated with cigarette smoking. Transplantation 71:1752-1757, 2001.

Lawrence Y. Agodoa, MD; Lawrence Appel, MD, MPH; George L. Bakris, MD; Akinlolu Ojo, MD, PhD; et al for the African American Study of Kidney Disease and Hypertension (AASK) Study Group. Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis. A Randomized Controlled Trial. JAMA. 285:2719-2728, 2001.

Herwig-Ulf Meier-Kriesche, Akinlolu O Ojo, Friedrich K Port, Julie A Arndorfer, Diane M Cibrik, Bruce Kaplan. Survival improvement among patients with end-stage renal disease: trends over time for transplant and wait-listed patients. J Am Soc Nephrol 12:1293-1296, 2001.

Ojo A, Meier-Kriesche H-U, Hanson J, Cibrik D, Leichtman A, Wolfe B, Agodoa L, Kaufman D, Kaplan B. Long-term benefit of kidney-pancreas transplants in type 1 diabetics. Transplant Proc 33:1670-1672, 2001.

Ojo A, Hanson J, Okechukwu N, Wolfe R, Leichtman A, Agodoa L, Kaplan B, Port F. Survival benefit of marginal kidneys versus maintenance dialysis. J Am Soc Neph 12:589-597, 2001.

Meier-Kriesche H-U, Ojo AO, Hanson JA and Kaplan B. Exponentially increased risk for infectious death in elderly renal transplant recipients: a comparison of transplanted and wait-listed end-stage renal disease patients. Kidney Int 59:1539-1543, 2001.

Meier-Kriesche H-U, Ojo A, Leichtman AB, Hanson J, Magee J, Rudich S, Cibrik D, Kaplan B.Interaction of HLA matching and mycophenolate mofetil on graft survival in renal transplantation. Transplantation 71:398-401, 2001.

Ojo AO, Meier-Kriesche H-U, Hanson JA, Leichtman AB, Magee JC, Cibrik D, Wolfe RA, Port FK, Agodoa L, Kuafman DB, Kaplan B. The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation 71:82-90, 2001.

Isaacs RB. Lobo PI. Nock SL. Hanson JA. Ojo AO. Pruett TL. Racial disparities in access to simultaneous pancreas-kidney transplantation in the United States . Am J Kidney Dis 36:526-33, 2000.

Meier-Kriesche H-U, Ojo AO, Hanson JA, Cibrik DM, Punch JD, Leichtman AB, Kaplan B. Increased impact of acute rejection on chronic allograft failure in the most recent era. Transplantation 70:1098-1100, 2000.

Meier-Kriesche H-U, Punch JD, Leichtman AB, Cibrik D, Ojo A, Hanson J and Kaplan B.The effect of mycophenolate mofetil on long term outcomes in African American renal transplant recipients. J Am Soc Neph 12:2366-2370, 2000.

Meier-Kriesche H-U, Kaza H, Palekar S, Friedman G, Mulgaonkar S, Ojo A, Kaplan B. The effect of daclizumab in a high risk renal transplant population. Clinical Transplantation 14:509-513, 2000.