Research Summary:

Molecular biology of glomerular disease.

Dr. Johnstone is the recipient of a 3-year Young Investigator Award (beginning July 1, 2008) from The NephCure Foundation for "Interactions of slit diaphragm protein Fat1 with conventional kinesin, microtubules and the actin cytoskeleton."

Link to PubMed Citations

Selected Publications:

Garg P, Verma R, Nihalani D, Johnstone DB, Holzman LB. Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization. Mol Cell Biol. 2007 Dec;27(24):8698-712. Epub 2007 Oct 8.

Johnstone DB, Holzman LB. Clinical impact of research on the podocyte slit diaphragm. Nat Clin Pract Nephrol. 2006 May;2(5):271-82. Review.