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Paul W. Gikas, M.D.

Research Summary:

After an initial assignment as Chief of the Laboratory Service at the Ann Arbor Veterans Administration Hospital, Dr. Gikas served as an attending pathologist on the Surgical and Autopsy Pathology Services at the University Hospital with special interest in nephropathology, genito-urinary pathology and the pathology of trauma. He served as director of the Clinical Electron Microscopy Unit and Director of the Autopsy Service in the Department of Pathology. His research activities included investigation of the pathogenesis of injuries in fatal automobile crashes. Results from these studies were used in testimony before Congressional committees in support of federal legislation which mandated safety standards for automobiles. He was also involved in research involving the preservation of blood for transfusion by freezing. Dr. Gikas retired from the Department of Pathology in 1995, and continues to provide service on a part time basis in nephropathology, the autopsy service and teaching as an Active Professor Emeritus.

Link to PubMed Citations

Selected Publications:

Wiebers DO, Elzanowski A, Gikas PW, Leaning J, White RD. Monkey business in space. Nature. 1997 Oct 9;389(6651):537.

Gikas PW, Del Buono EA, Epstein JI. Florid hyperplasia of mesonephric remnants involving prostate and periprostatic tissue. Possible confusion with adenocarcinoma. Am J Surg Pathol. 1993 May;17(5):454-60.

Francis IR, Gikas PW. Metastatic transitional cell carcinoma simulating primary ovarian malignancy. Urol Radiol. 1992;14(3):214-7.

Quint LE, Van Erp JS, Bland PH, Del Buono EA, Mandell SH, Grossman HB, Gikas PW. Prostate cancer: correlation of MR images with tissue optical density at pathologic examination. Radiology. 1991 Jun;179(3):837-42.

Quint LE, Van Erp JS, Bland PH, Mandell SH, Del Buono EA, Grossman HB, Glazer GM, Gikas PW. Carcinoma of the prostate: MR images obtained with body coils do not accurately reflect tumor volume. AJR Am J Roentgenol. 1991 Mar;156(3):511-6.

Grainger R, Gikas PW, Grossman HB. Urothelial carcinoma occurring within an inverted papilloma of the ureter. J Urol. 1990 Apr;143(4):802-4.

Quint LE, Glazer GM, Chenevert TL, Fechner KP, Gikas PW, Shireman PK, Grossman HB, Li KC. In vivo and in vitro MR imaging of renal tumors: histopathologic correlation and pulse sequence optimization. Radiology. 1988 Nov;169(2):359-62.

Ewald EA, Gikas PW, Castor CW. Periarticular fibrosis associated with idiopathic retroperitoneal fibrosis. J Rheumatol. 1988 Sep;15(9):1443-6.

Marasco WA, Gikas PW, Azziz-Baumgartner R, Hyzy R, Eldredge CJ, Stross J. Ibuprofen-associated renal dysfunction. Pathophysiologic mechanisms of acute renal failure, hyperkalemia, tubular necrosis, and proteinuria. Arch Intern Med. 1987 Dec;147(12):2107-16.

Bloom DA, DiPietro MA, Gikas PW, McGuire EJ. Extratesticular dermoid cyst and fibrous dysplasia of epididymis. J Urol. 1987 May;137(5):996-7.

Griffin DJ, Oke EJ, Cho KJ, Gikas PW. Chemical ablation of the canine kidney using sodium tetradecyl sulfate (Sotradecol). A histopathologic study. Invest Radiol. 1986 Mar;21(3):217-20.

Flint A, Gikas PW, Roberts JA. Alveolar soft part sarcoma of the uterine cervix. Gynecol Oncol. 1985 Oct;22(2):263-7.

Jasinski RW, Amendola MA, Glazer GM, Bree RL, Gikas PW. Computed tomography of renal oncocytomas. Comput Radiol. 1985 Sep-Oct;9(5):307-14.

Grossman HB, Sonda LP 3rd, Lloyd RV, Gikas PW. Carcinosarcoma of bladder. Evaluation by electron microscopy and immunohistochemistry. Urology. 1984 Oct;24(4):387-9.

Sonda LP, Grossman HB, MacGregor RJ, Gikas PW. Incidental adenocarcinoma of the prostate: the role of repeat transurethral resection in staging. Prostate. 1984;5(2):141-6.

Lloyd RV, Gikas PW, Chandler WF. Prolactin and growth hormone-producing pituitary adenomas. An immunohistochemical and ultrastructural study. Am J Surg Pathol. 1983 Apr;7(3):251-60.

Gikas PW. Forensic aspects of the highway crash. Pathol Annu. 1983;18 Pt 2:147-63.

Perlow DL, Gikas PW, Horowitz EM. Effect of vesical overdistention on bladder mucin. Urology. 1981 Oct;18(4):380-3.

Muthuswami SG, Tannen RL, Gikas PW. Membranous glomerulonephritis in renal allografts. N Engl J Med. 1980 May 22;302(21):1207.

Massari PU, Hsu CH, Barnes RV, Fox IH, Gikas PW, Weller JM. Familial hyperuricemia and renal disease. Arch Intern Med. 1980 May;140(5):680-4.

Hill JH, Graham MD, Gikas PW. Obliterative fibrotic middle ear disease in systemic vasculitis. Ann Otol Rhinol Laryngol. 1980 Mar-Apr;89(2 Pt 1):162-4.

Turcotte JG, Sweeton JC, Lesesne CB, Tsai CT, Harper ML, Bull RW, Gikas PW, Haines RF, Freier DT, Niederhuber JE. Renal allograft prolongation in DLA-mismatched beagles. Transplant Proc. 1979 Jun;11(2):1444.

Fischer CP, Herwig KR, Gikas PW. Adult renal myoepithelial hamartoma. Urology. 1978 Nov;12(5):594-7.

Deridder PA, Koff SA, Gikas PW, Heidelberger KP. Renal malacoplakia. J Urol. 1977 Apr;117(4):428-32.

Foley WD, Bookstein JJ, Tweist M, Gikas PW, Mayor GH, Turcotte JG. Arteriography of renal transplants. Radiology. 1975 Aug;116(02):271-7.

Weatherbee L, Spencer HH, Knorpp CT, Lindenauer SM, Gikas PW, Thompson NW. Coagulation studies after transfusion of hydroxyethyl starch protected frozen blood in primates. Transfusion. 1974 Mar-Apr;14(2):109-15.

Mena E, Bookstein JJ, McDonald FD, Gikas PW. Angiographic findings in renal medullary cystic disease. Radiology. 1974 Feb;110(2):277-81.

Mena E, Bookstein JJ, Gikas PW. Angiographic diagnosis of renal parenchymal disease. Chronic glomerulonephritis, chronic pyelonephritis, and arteriolonephrosclerosis. Radiology. 1973 Sep;108(3):523-32.

Turcotte JG, Feduska NJ, Haines RF, Freier DT, Gikas PW, McDonald FD, Johnson AG, Morrell RM, Thompson NW. Antithymocyte globulin in renal transplant krecipients. A clinical trial. Arch Surg. 1973 Apr;106(4):484-8.


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