Diarrhea that persists for more than a few days and continues after a traveler returns home is unlikely to be due to one of the common agents of Travelers Diarrhea. Therefore, ongoing diarrhea after travel deserves some attention and evaluation, since many causes respond to specific treatments. Some of the common causes of persistent diarrhea after travel are listed below:

• Parasitic protozoal infections (e.g., giardiasis, amebiasis, Cryptospordium or Cyclospora infection, Isospora infection)
• Other parasitic infections (e.g., Strongyloides infection, hookworm, schistosomiasis)
• Antibiotic-associated colitis (Clostridium difficile) after antibiotic self-treatment for travelers' diarrhea
• Secondary lactase deficiency after travelers' diarrhea
• Irritable bowel syndrome following an infectious diarrhea during travel
• New onset of inflammatory bowel disease, triggered by diarrhea infection during travel
• Tropical sprue

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