Faculty Appointment: Clinical Assistant Professor,
Department of Clinical Sciences,
University of Michigan College of Pharmacy

Additional Title: Clinical Pharmacist in Infectious Diseases,
Director, Pharmacy Specialty Residency in Infectious Diseases (PGY2)

Clinical Interests: Antimicrobial stewardship, Infection control & epidemiology

Research Interests: Antimicrobial resistance, drug interactions, antimicrobial drug allergies, nosocomial infections & outcomes, infections & antimicrobial use in patients with renal disease

Degree: 1999, Doctor or Pharmacy (Pharm.D.)
University of Michigan College of Pharmacy,
Ann Arbor, MI

1995, Bachelor of Science (B.S.)
Clinical Laboratory Sciences,
Michigan State University,
East Lansing, MI

Residency: 2001, Specialty Residency in Infectious Diseases University of Michigan Health System, Ann Arbor, MI

2000, ASHP Accredited Pharmacy Practice Residency
St. John Hospital & Medical Center, Detroit, MI

Faculty Appointment Date: 7/2001

Clinical office address UHB2D301 University Hospital
1500 E. Medical Center Drive
Ann Arbor, MI 48109-0008
Clinical office telephone: (734) 936-2473
Clinical office FAX: (734) 936-7027

Additional information: http://sitemaker.umich.edu/daryldd/home

RESEARCH/PRACTICE INTERESTS
Dr. DePestel practices, teaches, and conducts research in the areas of adult Infectious Diseases. He is currently a Clinical Assistant Professor at the University of Michigan College of Pharmacy and a Clinical Pharmacist in Infectious Diseases at the University of Michigan Health System. He is responsible for precepting pharmacy students and pharmacy residents in Infectious Diseases pharmacotherapy. Dr. DePestel was also recently awarded the Ortho-McNeil Janssen/Pricara Infectious Diseases Residency Award from the Society of Infectious Diseases Pharmacists. Dr. DePestel is currently the Chair of the American College of Clinical Pharmacy (ACCP) Infectious Diseases Practice & Research Network (ID-PRN) and is also co-chair of the membership committee for the Society of Infectious Diseases Pharmacists (SIDP).

RECENT PUBLICATIONS

Collins CD, Stuntebeck ER, DePestel DD, Stevenson JG. Pharmacoeconomic Analysis of Liposomal Amphotericin B versus Voriconazole for Empirical Treatment of Febrile Neutropenia. Clin Drug Investig. 2007;27(4):233-41.

Monto AS, DePestel DD. Facts or Fiction 2006: Influenza in America and Global Influences. U.S. Pharmacist 2006; December (Suppl):1-14. text

Saad AH, DePestel DD, Carver PL. Factors Influencing the Magnitude and Clinical Significance of Drug Interactions between Azole Antifungals and Select Immunosuppressants. Pharmacotherapy 2006;26:1730-1744.

Eschenauer G, Regal R, DePestel DD. Antibiotic Allergy. New England Journal of Medicine 2006;354:2293-2294.

Lin S, Carver PL, DePestel DD. Dalbavancin: A New Option for the Treatment of Gram-Positive Infections. Annals of Pharmacotherapy 2006;40:449-460.

Malani PN, DePestel DD, Riddell J, Bickley S, Klein LR, Kauffman CA. Experience with community-based amphotericin B infusion therapy. Pharmacotherapy. 2005;25(5):690-7.

Chenoweth CE, DePestel DD, Prager RL. Are cephalosporins adequate for antimicrobial prophylaxis for cardiac surgery involving implants? Clin Infect Dis. 2005;41(1):122-3; author reply 123-4.

DePestel DD, Kazanjian PH, Cinti SK, Kauffman CA, Carver PL. Assessing the Magnitude and Duration of Didanosine-Induced Elevation of Gastric pH in HIV-Infected Subjects. Pharmacotherapy 2004;24:1539-1545.

William AP Jr, DePestel DD, Ellis JJ, Regal RE. Incidence of Carbapenem-Associated Hypersensitivity Reactions among Penicillin Allergic Patients versus Patients without a Penicillin Allergy. Clinical Infectious Diseases 2004;38:1102-1107.

DePestel DD, Peloquin CA, Carver PL. Peritoneal Fluid Concentrations of Linezolid in the Treatment of Vancomycin-Resistant Enterococcus faecium Peritonitis. Pharmacotherapy 2003;23:1322-1326.

Kraft MD, Pasko DA, DePestel DD, Ellis JJ, Peloquin CA, Mueller BA. Clearance of Linezolid During Continuous Venovenous Hemodiafiltration. Pharmacotherapy 2003;23:1071-1075.

Regal RE, DePestel DD, VandenBussche HL. The Effect of an Antimicrobial Restriction Program on Pseduomonas aeruginosa Resistance to ß-Lactams in a Large Teaching Hospital. Pharmacotherapy 2003;23:618-624.