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Description of Research: Carol Chenoweth
Our research centers around the epidemiology of healthcare
associated infections and antibiotic resistant organisms:
Healthcare-associated infections
The major focus of our research has been the epidemiology
and prevention of hospital associated infections in
high risk patient populations. Our analysis of candidemia
in a children’s hospital identified that hyperalimentation
was an independent risk factor for candidemia in children.
In a similar type of study, mucositis was identified
as the key risk factor for the development of anaerobic
bacteremia bone marrow transplant recipients. Two
cohort studies have highlighted the prevalence of
nosocomial infections in patients undergoing high
risk procedures, such as extracorporeal membrane oxygenation
or left ventricular assist devices. We have two current
studies near completion on healthcare-associated infections
in the home setting.
Emerging antibiotic resistance
We have an interest in antibiotic resistant organisms
in community and hospital pathogens, especially antibiotic
resistant enterococci. A study of vancomycin-resistant
enterococcus colonization in patients awaiting liver
transplantation is in final stages of manuscript preparation.
In addition, we are participating in a multicenter
study to evaluated efficacy of control measures for
prevention of spread of vancomycin-resistant enterococci
and methicillin-resistant staphylococci in the ICU
setting.
Recent Publications
Chenoweth, CE; DePestel, DD; Prager, RL. Are cephalosporins
adequate for antimicrobial prophylaxis for cardiac
surgery involving implants? Letter to the Editor.
Clin Inf Dis 41(1): 122-123, 2005.
Cinti S, Chenoweth C, Monto AS. Preparing for pandemic
influenza: should hospitals stockpile oseltamivir?
Infect Contr Hosp Epid 26:852-854, 2005.
McNeil SA, Malani PN, Chenoweth CE, Fontana RJ, Magee
JC, Punch JD, Mackin ML, Kauffman CA. Vancomycin-resistant
enterococcal colonization and infection in liver transplant
candidates and recipients: A prospective surveillance
study. Clin Inf Dis 42: 195-203, 2006.
Washer LL, Chenoweth CD: Infection control strategies
for methicillin-resistant staphylococcus aureus and
vancomycin-resistant eterococcus: What is the evidence?
JCOM 2006; 13:333-341.
Borschel DM, Chenoweth CE, Kaufman SR, Hyde KV, VanDerElzen
KA, Raghunathan TE, Collins CD, Saint S. Are antiseptic-coated
central venous catheters effective in a real-world
setting? Am J Infect Control 34 (6): 388-393, 2006.
Day LJ, Chenoweth CE, Vander Hyde K, Lynch JP, Iannettoni
M, Clark NM: Risk factors for Aspergillosis following
lung transplantation. Infect Dis Clin Pract 14:283-288,
2006.
Malani A, Trimble K, Parekh V, Chenoweth C, Kaufman
S, Saint S. Review of clinical trials of skin antiseptic
agents used to reduce blood culture contamination.
Infect Control Hosp Epidemiol 2007; 28:892-895.
Washer LL, Riddell IV J, Rider J, Chenoweth CE. Mycobacterium
neoaurum bloodstream infections: report of 4 cases
and review of the literature. Clin Infect Dis 2007;
45:e10-13.
Cinti SK, Washer LL, Chenoweth CE. Clostridium difficile
colitis: A reemerging threat. J Clin Outcomes Management
14 (9): 505-514, 2007.
Chenoweth CE, Washer LL, Obeyesekera K, Friedman
C, Brewer K, Fugitt GE, Lark R. Ventilator-associated
pneumonia in the home care setting. Infect Contr Hosp
Epidemiol 28 (8): 910-915, 2007.
Cinti SK, Washer LL, Chenoweth CE. Clostridium difficile-associated
disease. Infectious Diseases Board Review Manual.
Hosp Phys 10 (3):1-12, 2007.
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