Skip to contentUniversity of Michigan Health System - link
Department of Internal Medicine - link
search this site

About Us

Info for Patients

Referring Physicians

Our Faculty

Education & Research

HIV/AIDS Treatment Program

What's Inside/Appt Scheduling

In the Spotlight
Take a Look
Web Resources

More News

Internal Resources

Internal Medicine Divisions


Drug Information Page

Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) work by binding tightly to the enzyme reverse transcriptase. This in turn, prevents viral RNA from being converted to viral DNA which infects healthy cells.

Viramune (nevirapine)

Usual Dosage

Starting dose: 1 X 200mg tablet once per day for the first 14 days
This lead-in dosing decreases the incidence of developing a rash from nevirapine.
Maintenance dose: 1 X 200mg tablet twice per day after the first 14 days
Tablets should be taken 12 hours apart, for example 7am and 7pm.

Can be taken with or without food.
If a dose is missed take the next as soon as possible. Do not double the next dose.

Side Effects to report to your doctor immediately

  • Fever
  • Fatigue
  • Nausea
  • Headache
  • Rash: Most occur within the first 6 weeks of therapy. If you develop a severe rash or a rash accompanied by fever, blisters, oral lesions, conjunctivitis, swelling, muscle or joint aches, or general malaise stop taking Viramune immediately and contact your doctor. Do not increase your dose to twice a day if you develop a rash in the first 14 days.

Drug Interactions and Incompatibility

  • Oral Contraceptives: May decrease the effectiveness. Therefore, you should not use these types of birth control while taking Viramune. A latex condom should always be used.
  • Notify your doctor of all the medications you are taking

All of your Antiviral Medications must be taken exactly as prescribed, without skipping or altering doses. Please notify you doctor if you have any problems with these or any of your medicines.


U-M Medical School
| Hospitals & Health Centers | U-M | TEXT-ONLY

University of Michigan Health System
1500 E. Medical Center Drive  Ann Arbor, MI 48109   734-936-4000
(c) copyright Regents of the University of Michigan
Template developed & maintained by: Public Relations & Marketing Communications
Contact UMHS

The University of Michigan Health System web site does not provide specific medical advice and does not endorse any medical or professional service obtained through information provided on this site or any links to this site.
Complete disclaimer and Privacy Statement


Health Topics A-Z

For Patients & Families

For Health Professionals

Search Tools & Index