Skip to contentUniversity of Michigan Health System - link
Department of Internal Medicine - link
search this site

About Us

Info for Patients

Referring Physicians

Our Faculty

Education & Research

HIV/AIDS Treatment Program

What's Inside/Appt Scheduling

In the Spotlight
Take a Look
Web Resources

More News

Internal Resources

Internal Medicine Divisions


Drug Information Page

Protease Inhibitors stop HIV replication by preventing the enzyme protease from cutting the virus into shorter pieces that it needs to make copies of itself in newly infected cells. New copies are still made but they are defective and not completely formed so they can't infect other cells.

 Lexiva (fosamprenavir)

Usual Dosage

2 X 700mg tablets twice per day (Dose will changed when given with Norvir)

May be taken with or without food

Side Effects to report to your doctor

  • nausea/diarrhea/vomiting
  • Loss of appetite
  • headache
  • Lipodystrophy
  • increased cholesterol and triglyceride levels
  • general feeling of malaise ("crummy feeling")

Drug Interactions

Lexiva dosage will be adjusted when taken with Norvir

St. John's Wort should not be taken with amprenavir as it lowers amprenavir levels in the blood.

Protease inhibitors can increase the effects of Viagra. Viagra doses should be lowered when taking with protease inhibitors.

All of your Antiviral Medications must be taken exactly as prescribed, without skipping or altering doses. Please notify you doctor if you have any problems with these or any of your medicines.


U-M Medical School
| Hospitals & Health Centers | U-M | TEXT-ONLY

University of Michigan Health System
1500 E. Medical Center Drive  Ann Arbor, MI 48109   734-936-4000
(c) copyright Regents of the University of Michigan
Template developed & maintained by: Public Relations & Marketing Communications
Contact UMHS

The University of Michigan Health System web site does not provide specific medical advice and does not endorse any medical or professional service obtained through information provided on this site or any links to this site.
Complete disclaimer and Privacy Statement


Health Topics A-Z

For Patients & Families

For Health Professionals

Search Tools & Index