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Protease Inhibitors stop HIV replication by preventing the enzyme protease from cutting the virus into shorter pieces that it needs to make copies of itself in newly infected cells. New copies are still made but they are defective and not completely formed so they can't infect other cells.

 amprenavir (Agenerase)

Usual Dosage

8 X 150mg capsules twice per day (Total dose 1200mg twice per day)

May be taken with or without food

Side Effects to report to your doctor

  • nausea/diarrhea
  • abdominal pain
  • headache
  • rash (should be reported to your doctor immediately)
  • increased cholesterol levels
  • numbing sensation on the skin
  • increased thirst, hunger, weight loss, urination, and fatigue (all signs of high blood sugar)

Drug Interactions

The drugs Hismanal, Propulsid, Halcion and Versed should not be taken with amprenavir.

The drug rifampin should not be taken with amprenavir as it lowers amprenavir levels in the blood.

Do not take Vitamin E supplements while taking amprenavir. 

Click here for more information on amprenavir.

All of your Antiviral Medications must be taken exactly as prescribed, without skipping or altering doses. Please notify you doctor if you have any problems with these or any of your medicines.


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