Nucleoside Reverse Transcriptase Inhibitors (NRTIs) work by being incorporated into the viral DNA, making it ineffective.

abacavir (Ziagen)

Dosage

1 X 300mg tablet twice per day

Side Effects to report to your doctor immediately (usually start within first 7-15 days of taking drug)

WARNING:    Hypersensitivity reactions have been associated with Ziagen. Any patient developing signs or symptoms of hypersensitivity (fever, skin rash, fatigue, nausea, vomiting, or diarrhea) should discontinue Ziagen immediately and contact their doctor. Ziagen should never be restarted following a hypersensitivity reaction.

• low grade fever and nausea/vomiting
• "general sick feeling" and flu-like symptoms (notify your doctor immediately)
• rash
• fatigue
• headache
• abdominal pain
• constipation
• dizziness

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