Frequently Asked Questions

about the research of H. David Humes, MD

Has Dr. Humes created a hemodialysis substitute for patients with chronic renal failure?

He is working on such a treatment, but what was reported recently in the press was success with the first component of it. The current achievement is a device that is promising as a new treatment for acute renal failure (not chronic renal failure) - a grave condition treated in hospital intensive care units. However, this is also the first step in a larger project that is aimed at developing an implantable bioartificial kidney for treating chronic renal failure. An implantable bioartificial organ would be a substitute for hemodialysis.

What is new in this?

The use of kidney cells (renal proximal tubule cells) in the device adds to the treatment of acute renal failure substances produced by the cells. These are lacking in current treatment. We hope these cell products will speed recovery of patients in acute renal failure. Furthermore, use of the cells in this device adds to our storehouse of knowledge which we are applying towards developing an implantable device for treating chronic renal failure.

When will an implantable bioartificial kidney be available?

Dr. Humes predicts he could begin human testing of an implantable device within 5 years. He cautions that there are many complicating factors that could delay the research (FDA approvals, technical set backs, funding) but this is his current target.

Can I volunteer?

There is no need for volunteers at this time. The current device will be tested on desperately ill individuals in acute renal failure, which is not something for which one one volunteers. The implantable bioartificial kidney is too far in the future to consider volunteers just yet. However, we are collecting names for possible future contact. Leave your contact information on the University of Michigan Telecare recorded message line:

1-800-742-2300, # 6500

Local calls: 763-9000 #6500

How can I learn more about this work?

How can I support this work?

Contact the Medical Center Alumni and Development Office

301 E. Liberty, Suite 300

Ann Arbor, Michigan 48104

Address you inquiry to the attention of Mary Young