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Rachel Morgan Mentor: David Fox, M.D.
Research Description CD13 (aminopeptidase N) has been indicated to possibly be involved in rheumatoid arthritis, although its function in disease is undetermined. CD13 has been shown to be upregulated by the inflammatory cytokine IL-17 by the Fox lab. Another group has proposed the idea that soluble CD13 could act as a chemoattractant. I am exploring the possible role CD13 may have in rheumatoid arthritis and examining its immune function.
Publications Downing B, Morgan R, VanHulle K, Deem A, Malkova A. Large inverted repeats in the vicinity of a single double-strand break strongly affect repair in yeast diploids lacking Rad51. Mutat Res. 2008 Oct 14;645(1-2):9-18. Epub 2008 Aug 5
Rackham Merit Fellowship
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