Beth Lubeck
e-mail address: balubeck@umich.edu

Mentor: Philip King, PhD

Research Description

My research focuses on the role of Ras GTP-ase activating protein (GAP)
p120 RasGAP in immune function and development. Specifically, I am
interested in determining the importance of the GAP domain of p120 RasGAP
in these processes. Currently I am working on determining which aspects of
the p120 RasGAP knockout phenotype are dependent on GAP activity by
generating mice with a point mutation in the p120 RasGAP GAP domain.

Publications

Lapinski PE, Kwon S, Lubeck BA, Wilkinson JE, Srinivasan RS, Sevick-Muraca E, King PD. 2012. RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice. J Clinical Invest 122(2):733-47

Abstracts




Awards