Thomas Moore, Ph.D.
Bhan U, Lukacs NW, Osterholzer JJ, Newstead MW, Zeng X , Moore TA, McMillan TR, Krieg AM, Akira S, Standiford TJ. TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells. J Immunol . 2007 Sep 15;179(6):3937-46.
Lindell DM, Moore TA , McDonald RA, Toews GB, Huffnagle GB. Distinct compartmentalization of CD4+ T-cell effector function versus proliferative capacity during pulmonary cryptococcosis. Am J Pathol . 2006 Mar;168(3):847-55.
Horowitz JC, Cui Z, Moore TA, Meier TR, Reddy RC, Toews GB, Standiford TJ, Thannickal VJ. Constitutive activation of prosurvival signaling in alveolar mesenchymal cells isolated from patients with nonresolving acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol . 2006 ar;290(3):L415-25
Moore BB , Kolodsick JE , Thannickal VJ , Cooke K , Moore TA , Hogaboam C , Wilke CA , Toews GB . Interferon-inducible protein 10, but not monokine induced by gamma interferon, promotes protective type 1 immunity in murine Klebsiella pneumoniae pneumonia. Infect Immun . 2005 Dec;73(12):8226-36.
Moore TA, Lau HY, Cogen AL, Standiford TJ. Defective innate antibacterial host responses during murine Klebsiella pneumoniae bacteremia: tumor necrosis factor (TNF) receptor 1 deficiency versus therapy with anti-TNF-alpha. Clin Infect Dis . 2005 Aug 1;41 Suppl 3:S213-7.
Lindell DM, Moore TA , McDonald RA, Toews GB, Huffnagle GB. Generation of antifungal effector CD8+ T cells in the absence of CD4+ T cells during Cryptococcus neoformans infection. J Immunol. 2005 Jun 15;174(12):7920-8.
Moore BB, Kolodsick JE, Thannickal VJ, Cooke K, Moore TA , Hogaboam C, Wilke CA, Toews GB. CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury. Am J Pathol . 2005 Mar;166(3):675-84.
Zeng X, Moore TA , Newstead MW, Deng JC, Kunkel SL, Luster AD, Standiford TJ. IP-10 mediates selective mononuclear cell accumulation and activation in response to intrapulmonary transgenic expression and during adenovirus-induced pulmonary inflammation. J Interferon Cytokine Res . 2005 Feb;25(2):103-12.
Deng JC, Moore TA , Newstead MW, Zeng X, Krieg AM, Standiford TJ. CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection. J Immunol . 2004 Oct 15;173(8):5148-55.
Deng JC, Zeng X, Newstead M, Moore TA , Tsai WC, Thannickal VJ, Standiford TJ. STAT4 is a critical mediator of early innate immune responses against pulmonary Klebsiella infection. J Immunol . 2004 Sep 15;173(6):4075-83.
Moore TA, Lau HY, Cogen AL, Monteleon CL, Standiford TJ. Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. Shock . 2003 Oct;20(4):309-15.
Moore TA, ML Perry, AG Getsoian, CL Monteleon , AL Cogen, and TJ Standiford. Increased mortality and disregulated cytokine production in TNFR1 deficient mice following systemic Klebsiella pneumoniae infection. Infect Immun , 2003 Sep;71(9):4891-900.
Zeng X, TA Moore, MW Newstead, R Hernandez-Alcoceda, WC Tsai, and TJ Standiford. Intrapulmonary expression of macrophage inflammatory protein 1??(CCL3) induces neutrophil and NK cell accumulation and stimulates innate immunity in murine bacterial pneumonia. Infect Immun 71:1306, 2003.
Zeng X, Moore TA , Newstead MW, Hernandez-Alcoceba R, Tsai WC, Standiford TJ. Intrapulmonary expression of macrophage inflammatory protein 1alpha (CCL3) induces neutrophil and NK cell accumulation and stimulates innate immunity in murine bacterial pneumonia. Infect Immun . 2003 Mar;71(3):1306-15.
Moore, TA, ML Perry, AG Getsoian, MW Newstead, and TJ Standiford. Divergent role of Interferon in a murine model of pulmonary versus systemic Klebsiella pneumoniae infection. Infect Immun 70:6310, 2002.
Tateda K, Moore TA, Deng JC, Newstead MW, Zeng X, Matsukawa A, Swanson MS, Yamaguchi K, and Standiford TJ. Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophilia pneumonia. J Immunol 166:3355, 2001.