Massimo Pietropaolo, M.D.
Director, Laboratory of Immunogenetics
Brehm Scholar
Brehm Center for Type 1 Diabetes Research and Analysis
Associate Professor of Internal Medicine, Pediatrics

maxtp@umich.edu

Research Interests:

Islet cell autoimmunity in Type 1 and Type 2 Diabetes; identification of novel molecular targets of autoimmune diabetes; prediction of Type 1 Diabetes; epidemiology of islet cell autoimmunity in Type 2 diabetes; genetics of Type 1 Diabetes; proteomics in Type 1 Diabetes

Recent Publications:

Pietropaolo M , Barinas-Mitchell E, Kuller LH. The heterogeneity of diabetes: unraveling a dispute: is systemic inflammation related to islet autoimmunity? Diabetes. 2007 May;56(5):1189-97.

Oral EA, Pietropaolo M . Editorial: Metabolism lessons for survival: when adults and children are not alike. J Clin Endocrinol Metab. 2006 Oct;91(10):3763-5.

Barinas-Mitchell E, Kuller LH, Pietropaolo S, Zhang YJ, Henderson T, Pietropaolo M . The prevalence of the 65-kilodalton isoform of glutamic acid decarboxylase autoantibodies by glucose tolerance status in elderly patients from the cardiovascular health study. J Clin Endocrinol Metab. 2006 Aug;91(8):2871-7.

Pietropaolo M , Yu S, Libman IM, Pietropaolo SL, Riley K, LaPorte RE, Drash AL, Mazumdar S, Trucco M, Becker DJ. Cytoplasmic islet cell antibodies remain valuable in defining risk of progression to type 1 diabetes in subjects with other islet autoantibodies. Pediatr Diabetes. 2005 Dec;6(4):184-92.

Casu A, Trucco M, Pietropaolo M . A look to the future: prediction, prevention, and cure including islet transplantation and stem cell therapy. Pediatr Clin North Am. 2005 Dec;52(6):1779-804.

Pietropaolo M. An 18-year-old patient with type 1 diabetes undergoing surgery. PLoS Med. 2005 May;2(5):e140.

McInerney MF, Najjar SM, Brickley D, Lutzke M, Abou-Rjaily GA, Reifsnyder P, Haskell BD, Flurkey K, Zhang YJ, Pietropaolo SL, Pietropaolo M , Byers JP, Leiter EH. Anti-insulin receptor autoantibodies are not required for type 2 diabetes pathogenesis in NZL/Lt mice, a New Zealand obese (NZO)-derived mouse strain. Exp Diabesity Res. 2004 Jul-Sep;5(3):177-85.

Strotmeyer ES, Yang Z, LaPorte RE, Chang YF, Steenkiste AR, Pietropaolo M , Nucci AM, Shen S, Wang L, Wang B, Dorman JS. Infant diet and type 1 diabetes in China . Diabetes Res Clin Pract. 2004 Sep;65(3):283-92.

Barinas-Mitchell E, Pietropaolo S, Zhang YJ, Henderson T, Trucco M, Kuller LH, Pietropaolo M . Islet cell autoimmunity in a triethnic adult population of the Third National Health and Nutrition Examination Survey. Diabetes. 2004 ay;53(5):1293-302.