David Aronoff, M.D.
Associate Professor of Internal Medicine,
Division of Infectious Diseases
Associate Professor of Microbiology & Immunology
daronoff@umich.edu

http://sitemaker.umich.edu/aronoff.lab/home


Research Focus

Mucosal immunology of the female reproductive tract and the gastrointestinal tract.

Particular areas of interest include innate immunity, epithelial cell and macrophage biology, cell signaling, and the regulation of host defense by lipid mediators and G protein coupled receptors.


Research Interests

Female reproductive tract infections and bacterial pneumonia. Particular areas of interest include innate immunity, epithelial cell and macrophage biology, cell signaling, and the regulation of host defense by lipid mediators and G protein coupled receptors.

Current Research Activity

My lab studies host-microbial interactions with a focus on bacterial infections that cause severe disease. Pathogens of interest include beta-hemolytic streptococci that cause postpartum infections and preterm delivery and toxigenic clostridia that cause toxic shock and colitis. We pair in vitro and in vivo studies with translational and interdisciplinary approaches to define critical steps in microbial pathogenesis and host immune defense. The overarching goal of the Aronoff lab is to identify novel preventive and therapeutic targets against infectious diseases through fundamental studies of disease pathogenesis.

Recent Publications

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=aronoff+dm%5BAuthor%5D