We list here Immunologists who comprise the faculty of the Immunology Program. Please click on their names to view more infromation about them.

 

Name Title Research Focus
D. Keith Bishop Professor, Surgery Transplantation immunology, immunosuppressive gene therapy; regulation of T cell mediated immunity
Marilia Cascalho Associate Professor of Surgery, Microbiology & Immunology B cell memory, B cell and immunoglobulin dependent T cell development and function and generation of diversity in health and disease
Maria Castro

Professor, Neurosurgery
Professor, Cell and Developmental Biology

Development of immunotherapies for primary and metastatic brain cancer: from basic immunobiology mechanisms to translational immune-therapeutics. Tumor immune-microenvironment: its role in tumor progression and response to therapeutics. Cross talk between cancer cells and hematopoietic stem/progenitor cells. Mechanisms affecting the migration of immune cells from peripheral lymphoid organs to the tumor microenvironment

Cheong-Hee Chang Professor, Microbiology & Immunology Regulation of innate-like CD4 T cell development and function
Grace Chen Assistant Professor,
Internal Medicine, Hematology/Oncology
Inflammation and cancer; role of gut microbiota and Nod-like receptors in colitis and cancer
Stephen Chensue Professor, Pathology Cellular and molecular mechanisms of leukocyte mobilization during granulomatous formation; pathology
Kathleen Collins Professor, Internal Medicine, Microbiology & Immunology Viral pathogenesis; antiviral immunity
Jeffrey Curtis Professor, Internal Medicine, Pulmonary and Critical Care

Lung immunity in humans and mice.
Specifically: immunopathogenesis of COPD; Efferocytosis; Interactions of lung leukocytes with the lung microbiome.
 

Raymond Douglas Associate Professor of Ophthalmology Thyroid eye disease; Autoimmunity; Fibrosis; Extracellular matrix; Cell signaling
Colin Duckett Professor, Pathology and Internal Medicine Analysis of the roles played by the IAP (Inhibitor of apoptosis) proteins in signal transduction and the control of programmed cell death. Deregulated activities of IAPs in disorders of lymphoid homeostasis, metabolic disease and cancer.
James Ferrara Professor, Pediatrics and Communicable Diseases Bone marrow transplantation, immune mechanisms of graft versus host disease; graft versus tumor reactions
David Fox Professor, Internal Medicine, Rheumatology

Human T lymphocyte biology,
rheumatoid arthritis, T cell interactions with synovial cells, regulation of TH17 cells

Irina Grigorova Assistant Professor, Microbiology & Immunology

Regulation and control of humoral (antibody) immune response; intravital imaging and quantitative analysis of lymphocyte dynamic behavior in living
mice.

Joseph Holoshitz Professor, Internal Medicine, Rheumatology

Signal transduction, small molecules and immunomodulatory peptides in autoimmunity; Gene-environment interaction in autoimmunity;Molecular mechanisms of MHC-disease association

David Irani Associate Professor, Neurology Neuroimmunology; immunopathogenesis of viral infections of the central nervous system; innate immunity to viruses; immune mechanisms of neuronal and glial cell injury
Michelle Kahlenberg Assistant Professor,
Internal Medicine, Rheumatology
The interplay between innate immunity and autoimmune disease development.  Specifically, I am interested in the inflammasome and how it relates to skin and other organ damage in autoimmune disease.
Venkat Keshamouni Associate Professor, Internal Medicine, Pulmonary and Critical Care Cancer cell and host immune cell interactions in tumor microenvironment; Tumor tolerance mechanisms; TGF-b and TLR signaling
Philip King Associate Professor, Microbiology & Immunology Intracellular signaling pathways controlling T lymphocyte activation, differentiation and death. Lymphatic vessel biology, cancer and angiogenesis
Ilona Kryczek Research Assistant Professor, Surgery

Tumor immunoediting, Inflamation, Human immunology

Steven Kunkel Professor, Pathology Epigenetics, chemokine and cytokine biology
Yasmina Laouar Assistant Professor, Microbiology & Immunology

Immunology/Mechanisms of Immunosuppression

Qiao Li Research Associate Professor, Surgery Development of cancer immunotherapy using immune cells, such as T cells,
B cells and dendritic cells (DCs). Use of in vivo primed and in vitro activated effector T and B cells for cancer treatment, and generate DC-based cancer stem cell vaccines to target cancer stem cells
Pedro Lowenstein Professor, Neurosurgery
Professor, Cell and Developmental Biology
The current focus of my research program is to discover the cellular, molecular, and mathematical basis underlying the growth patterns of malignant brain tumors, and the interactions between cancer cells with the tumor microenvironment, in both experimental models and in human patients suffering from malignant brain tumors
Nicholas Lukacs Professor, Pathology Pulmonary immune responses to allergens and viral infections. Role of cytokines and chemokines
Gary Luker Associate Professor, Radiology, Microbiology & Immunology, Biomedical Engineering

Chemokines and chemokine receptor signaling in cancer; molecular imaging

Carey Lumeng Assistant Professor, Pediatrics and Communicable Diseases

Obesity and Inflammation.  Adipose tissue macrophages and lymphocyte activation with obesity.  Dietary influences on inflammatory cell activation. Intravital microscopy on adipose tissue leukocytes

Steven Lundy Research Assistant Professor,
Internal Medicine
, Rheumatology

Regulation of the immune system in autoimmunity, asthma, cancer and infections by B lymphocytes

Ivan Maillard Associate Professor, Internal Medicine, Cell and Developmental Biology

Notch signaling, hematopoietic stem cells, T cell differentiation and homeostasis, bone marrow transplantation, alloimmunity, autoimmunity

Peter Mancuso Associate Professor, Environmental Health Sciences

Regulation of the innate immune response against bacterial pneumonia, Role of the eicosanoids and their receptors in pneumococcal pneumonia, Impact of second hand tobacco smoke in lung disease, Role of adiponectin and leptin in inflammation and infection in obesity

Yang Mao-Draayer Associate Professor, Neurology Neuroimmunology; the Interplay between immune system and neural stem/progenitor cells in multiple sclerosis (MS); cytokine, neurotrophin production and neuroprotective mechanisms for neuroregeneration in MS. The mission is to enhance translational research by bridging basic research in neuroimmunology with human studies in MS
David Markovitz Professor, Internal Medicine, Division of Infectious Diseases

The role of DEK in cancer and autoimmunity; the role of vimentin in the immune response; endogenous retroviruses; development of antiviral agents

Bethany Moore Professor, Internal Medicine, Pulmonary and Critical Care Chemokine, cytokine and eicosanoid regulation of pulmonary fibrosis; pulmonary infections post bone-marrow transplant
Thomas Moore

Research Assistant Professor, Internal Medicine, Pulmonary and Critical Care

Innate host responses during bacterial infection, microbial pathogenesis, T cells and bacterial infection
Gabriel Nuñez Professor, Pathology

Nod-like receptors; Host defense against bacterial pathogens; Mucosal Immunity; Role of the microbiota in immunity and pathogen eradication; Inflammatory disease; inflammation and cancer

Michal Olszewski Assistant Professor, Internal Medicine, Pulmonary and Critical Care Interface of the adaptive and innate immunity during host-pathogen interactions
Mary
O' Riordan
Associate Professor, Microbiology & Immunology Innate immunity to intracellular bacterial pathogens

John Osterholzer

Assistant Professor, Internal Medicine Pulmonary and Critical Care Investigating the recruitment and function of myeloid cells (monocytes, dendritic cells, and macrophages) that accumulate in the lung in response to infection and/or injury
Marc Peters-Golden Professor, Internal Medicine, Pulmonary and Critical Care lipid mediator actions, receptors, and signaling in inflammation, innate immunity, and pulmonary fibrosis
Sem Phan Professor, Pathology Inflammatory/immune responses and tissue injury and repair
Massimo Pietropaolo Professor Internal Medicine and Pediatrics Molecular mechanisms of islet cell autoimmunity in Type 1 diabetes
Autoimmunity, Autoantibodies
Jeffrey Platt Professor of Surgery,
Microbiology and Immunology
Transplantation immunology, accommodation, immunologic properties and genomic stability of stem cells, genetic basis of cell transformation and oncogenesis
Malini Raghavan Professor, Microbiology and Immunology Antigen presentation and HLA polymorphisms in infection
Pavan Reddy Professor, Internal Medicine Bone marrow transplantation, GVHD/GVL
Bruce Richardson Professor, Internal Medicine, Rheumatology Epigenetic mechanisms altering T cell function in autoimmunity and aging; Molecular mechanisms causing lupus; Mechanisms predisposing women to autoimmunity, Epigenetic changes caused by environmental agents, Role of oxidative damage in epigenetic alterations
Amr Sawalha Associate Professor,
Internal Medicine, Rheumatology

Genetics and epigenetics of complex autoimmune and inflammatory diseases; T cell DNA methylome in health and disease; functional genomics and systems biology in lupus and systemic vasculitis; Epigenomic variability and disease mechanisms  

Benjamin Segal Professor of Neurology Neuroimmunology; autoimmune diseases of the nervous system; cytokine and chemokine networks/ leukocyte interactions in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis
Theodore Standiford Professor, Internal Medicine, Pulmonary and Critical Care Lung inflammation
Lloyd Stoolman Professor, Pathology Lymphocyte recirculation and migration; Immunotherapy of malignant disease; T-cell trafficking during normal and pathologic immune responses; regulation of adhesion receptors involved in T-cell trafficking
Peter Ward Godfrey D. Stobbe Professor of Pathology Regulation and role of complement activation products, adhesion-promoting molecules and cytokines in the inflammatory response and in sepsis; signaling pathways in phagocytes; role of complement in sepsis
Christiane Wobus Assistant Professor,
Microbiology & Immunology

Mechanisms of norovirus – host interactions with macrophages, dendritic cells, and the gastrointestinal tract
Raymond Yung Professor, Internal Medicine, Gerontology

Prenatal diet and late life diseases;
Inflammation and aging; Dendritic cell cancer immunotherapy in aging

Weiping Zou Professor, Surgery Tumor immunity and immune vaccination

 


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