Crohn's Disease Imaging Studies
A prospective evaluation of computed tomography enterography (CTE) in assessing Crohn's disease activity
Principal Investigator: Ellen Zimmermann, MD
The main purpose of this 3-year study is to find out if there is a relation between computed tomography enterography (CTE) and magnetic resonance enterography (MRE) findings and clinical assessments in patients with Crohn's disease. Each patient will have 3 scans at 1-year intervals, and the patient's Crohn's Disease Activity Index (CDAI) will be calculated for the 7 days prior to each scan and certain laboratory values, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), will be obtained close to the scan date. This study will help to better define the role of CTE and MRE in evaluating Crohn's disease.
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FINCH – Observational multicenter study in patients with Crohn's disease for characterization of magnetic resonance enterography (MRE) assays for assessment of disease activity
Principal Investigator: Peter Higgins, MD, PhD, MSc
Enrollment Status: CLOSED
This study is assessing MRE as an alternative imaging method for the assessment of inflammatory status in patients with Crohn's disease. If it is determined that a patient is eligible to participate in this study, they will visit the University of Michigan multiple times over the course of 4 weeks. They will undergo one ileocolonoscopy within the first 2 weeks and two MREs over the course of the second 2 weeks. In addition, our study team will monitor the participant's physical condition by performing various tests, such as vital sign measurements, physical examinations, and blood draws.
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