The purpose of this study is to test whether a specific imaging sequence used during an MRI scan, called an MT-MRI, could be used as a non-invasive method for differentiating between fibrotic (scarring) and inflammatory intestinal strictures in Crohn's disease. Being able to detect the difference between fibrosis and inflammation would lead to better knowledge of how to treat that patient. Having a non-invasive means of monitoring disease progression and development of fibrosis would be useful in determining when patients would benefit from starting different therapies, so as to decrease or prevent permanent intestinal fibrosis without unduly exposing patients to side effects of serious medications.
This is a registry study to collect information on the long-term use and safety of Cimzia® as compared to other Crohn's disease medications prescribed by your doctor in routine clinical practice. Patients enrolled in this study will complete surveys about their social and medical history. Additionally, at your regularly scheduled office visits, you will be asked to provide information regarding your CD symptoms and other relevant information about your health and medications. UCB Inc. is the sponsor for this study. Patients who have been prescribed Cimzia® by their physician to treat CD are able to participate in this study.
This is a registry study to collect information on the long-term use and safety of Tysabri® as compared to other Crohn's disease medications prescribed by your doctor in routine clinical practice. Elan Pharmaceuticals is the sponsor of this study. Eligible patients are those who have been prescribed Tysabri® by their physician for the treatment of Crohn's disease.
In this study we collect information on patients with IBD and their family. We are interested in the demographics, genetics, and extent of disease at this time. Participants in this study give a blood sample for genetic analysis, take surveys bi-annually, and have intestinal tissue collected during colonoscopies. In the future, we plan to collect stool samples as well. The goals of this study are to find out what factors put people at risk of having Inflammatory Bowel Disease, which risk factors make people more likely to have specific types of disease or more severe disease, and to better understand how the immune system works in people with IBD. Adults with IBD and their family are welcome to participate.