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UMich HISTOLOGY VIRTUAL SLIDE LIST

Medical Histology, University of Michigan Medical School

compiled by Dr. Kent Christensen, Ph.D., J. Matthew Velkey, Ph.D., Lloyd M. Stoolman, M.D., Laura Hessler, and Diedra Mosley-Brower

Some items in the list contain numbers in brackets that give coordinates where you can find a good example of a specified structure on that slide. These X, Y coordinates can be read at the bottom of the computer screen when you view a virtual slide with the ImageScope. The coordinates indicate the exact location of the mouse pointer at a given moment. To view a structure indicated by the bracketed XY coordinate numbers in the list, go to the Tools (or Image) menu, click "Go To ...", and then enter the two coordinates (X and then Y). Click "Go To: Center," and then "Close," The item will be in the center of the screen, and you can view it at any magnification you please.

Want to see even more? Dr. Kent Christensen has compiled an even more extensive index combining the University of Iowa AND the UMich collections: http://www.med.umich.edu/histology/slidebox.htm

!! If you are a WINDOWS USER on campus, remember to map a drive to the file server (click here), and USE THE [WinLab] LINKS!!

 
EPITHELIAL TISSUE

029-1

Small intestine, H&E, 40X (simple columnar epithelium, simple squamous epithelium).

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176

Colon, H&E, 20X (simple columnar epithelium).

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009-N1

Kidney, H&E, 40X (simple cuboidal epithelium).

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210

Kidney, H&E, 20X (simple cuboidal epithelium).

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030

Mesentery, H&E, 40X (simple squamous epithelium in blood vessels and at surface).

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153

Esophagus, H&E, 20X (stratified squamous epithelium, nonkeratinized).

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250-1

Vagina, H&E, 40X (stratified squamous epithelium, nonkeratinized).

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106

Thick skin, sole of foot, H&E, 40X (stratified squamous epithelium, keratinized).

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020

Trachea, H&E, 20X and 40X (pseudostratified columnar epithelium).

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040

Trachea (pseudostratified columnar epithelium).

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019-2

Ureter, undistended, H&E, 20X (transitional epithelium).

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019-1

Ureter, over distended, H&E, 20X (transitional epithelium).

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CONNECTIVE TISSUE

029-1

Small intestine, H&E, 40X (loose, areolar connective tissue, fibroblasts, plasma cells, neutrophils).

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040

Trachea (connective tissue, plasma cells, elastic fibers).

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020

Trachea, H&E, 20 (connective tissue).

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020

Trachea, same area, 40X (connective tissue, fibroblast, plasma cell [4835 x 13692] ).

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026

Lymph nodes, H&E, 20X (orientation).

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026

Lymph nodes, same area, 40X (macrophage [28114 x 7744] in medulla).

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152

Pharynx, H&E, 20X (fat cell, elastic fibers).

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030

Mesentery, H&E, 20X (fat cells).

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160

Stomach, PAS & Azure II stains, 40X (mast cells [65044 x 12331]).

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033

Thin skin, stained for elastin, H&E, 20X (dermis, dense irregular connective tissue, elastic fibers).

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250-1

Vagina, H&E, 40X (dense irregular connective tissue).

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027

Lymph node, H&E, 40X (orientation).

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028

Lymph node, silver stain, 40X (reticular connective tissue, argyrophilic reticular fibers).

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034

Tendon, cross section, H&E, 20X (dense regular connective tissue).

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035

Tendon and muscle, longitudinal section, H&E, 20X (dense regular connective tissue).

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106

Foot, sole, flexor tendon, longitudinal section, H&E, 40X (dense regular connective tissue).

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036

Aorta, cross section, stained for elastin, 20X (concentric rings of elastin).

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MUSCLE

058L

Skeletal muscle, longitudinal section, H&E, 20X and 40X (banding pattern A I Z H [60787 x 18392, 34840 x 9034, 64339 x 17968]).

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058Lex

Skeletal muscle, longitudinal section, H&E, 40X.

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058T

Skeletal muscle, cross section, H&E, 40X.

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059-1

Fetal forearm muscle, Xsect., H&E, 40X (fascicle, epimysium, perimysium, endomysium).

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059-3

Fetal forearm muscle, Masson, 40X (fascicle, epimysium, perimysium, endomysium).

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057

Heart, ventricle, H&E, 40X (cardiac muscle, intercalated discs [for example, 10289 x 30470]).

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098-1

Heart, ventricle, H&E, 40X (cardiac muscle, intercalated discs). See Cardiovascular section.

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305

Heart, H&E, 40X (cardiac muscle, intercalated discs). See Cardiovascular section.

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029-1

Small intestine, H&E, 40X (smooth muscle). See Epithelium/CT section.

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169

Small intestine, H&E, 40X (smooth muscle).

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155

Stomach, H&E, 20X (smooth muscle).

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250-1

Vagina, H&E, 40X (stratified squamous epithelium, nonkeratinized).

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250-2

Vagina, Masson trichrome stain, 40X (smooth muscle). See Female Reproduction section.

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PERIPHERAL NERVOUS TISSUE

065-1

Spinal cord, cross section, Masson, 40X (spinal cord, neuron, dorsal root ganglion).

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065-1N Spinal cord, cross section, Masson, 40X (spinal cord, neuron, dorsal root ganglion).

065-2

Spinal cord, cross section, H&E, 40X (spinal cord, neuron, dorsal root ganglion)

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074

Sympathetic ganglion, probably methylene blue stain, 40X.

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250-1

Vagina, H&E, 40X (nerve fibers and parasympathetic ganglion [37144 x 14372]).

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250-2

Vagina, Masson trichrome stain, 40X (nerve fibers and parasympathetic ganglion)

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075

Seminal vesicle, H&E, 20X (parasympathetic ganglion).

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075

Seminal vesicle, H&E, 40X (parasympathetic ganglion [40928 x 3272]).

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068

Peripheral nerve, cross section, 40X (fascicle, axon, endoneurium, perineurium, epineurium)

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067

Peripheral nerve, longitudinal section, H&E, 40X (axon, myelin, node of Ranvier [21384 x 3607, 22829 x 5250]).

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029-1

Small intestine, H&E, 40X (myenteric plexus [21221 x 16904, 75135 x 16956]).

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071-2B

section, H&E, 40X (neuromuscular spindle [8993 x 10835]).

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071-2A

Muscle fibers, stain, 20X (motor end plate = neuromuscular junction [5637 x 9056]).

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SKIN and MAMMARY GLAND

106

Thick skin, sole of foot, H&E, 40X (thick skin, strata basale, spinosum, granulosum and corneum).

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112

Thick skin, sole of foot, 40X (thick skin, similar to 106).

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112N Thick skin, sole of foot, 40X

033

Thin skin, stained for elastin, 20X (elastic fibers in the dermis).

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105-1

Thin skin, H&E, 40X (hair follicle).

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105-2

Thin skin, H&E, 40X.

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107

Scalp, hair, H&E, 20X and 40X (hair follicle, external root sheath, sebaceous gland, arrector pili).

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106

Thick skin, H&E, 40X (eccrine sweat gland; more and better in 107 40X).

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109-1

Perianal region, Masson, 20X (apocrine sweat gland, myoepithelial cell).

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109-2

Perianal region, H&E, 20X (at lower left, apocrine sweat gland, myoepithelial cell).

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265

Nipple and areola, H&E, 20X (lactiferous duct, arrector pili muscle ).

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259

Inactive mammary gland of nulliparous female, H&E, 20X (lobule, duct)

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258

Active mammary gland, H&E, 40X (pregnant but not lactating, alveolus, myoepithelial cell).

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CARTILAGE, BONE, and BONE DEVELOPMENT

040

Trachea, H&E, 40X (hyaline cartilage).

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126

Trachea and esophagus, H&E, 40X (hyaline cartilage, in trachea at upper left).

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044

Ear pinna, aldehyde fuchsin and Masson, 20X (elastic cartilage).

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044H

Epiglottis, H&E, 20X (elastic cartilage).

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045

Intervertebral disc, H&E, 40X (fibrocartilage and dense irregular connective tissue, nucleus pulposus).

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046HF

Fetal face, frontal section, H&E, 40X (intramembranous bone formation in maxilla, osteocyte, osteoblast, osteoclast).

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046M

Fetal face, frontal section, 40X (intramembranous bone formation in maxilla, osteocyte, osteoblast, osteoclast).

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120

Fetal face and jaw, frontal section, H&E, 40X (intramembranous bone formation in maxilla).

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115-N

Palate, saggital section, H&E, 40X (intramembranous bone formation, spongy bone, compact bone).

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115-M

Palate, saggital section, Masson, 40X (intramembranous bone formation, spongy bone, compact bone).

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048

Fetal leg, cross section, H&E, 40X (spongy bone, osteoblast, osteoclast [36859 x 38075], appositional bone growth on surface of long bone).

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048b

Fetal leg, cross section, Masson, 40X (spongy bone, appositional bone growth on surface of long bone).

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108

Finger, H&E, 20X (endochondral bone formation, various zones).

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110

Finger, H&E, 20X (endochondral bone formation).

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049

Developing long bone, H&E, 20X (epiphyseal plate, zones of proliferation, hypertrophy, calcification and ossification).

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049

Developing long bone, H&E, 40X (epiphyseal plate, zones of proliferation, hypertrophy, calcification and ossification).

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050

Decalcified bone, cross section, H&E, 20X (compact bone, osteon=Haversian system).

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051

Ground section of compact bone, longitudinal, 20X (osteon=Haversian system, lacunae for osteocytes, canaliculus, Volkmann's canal).

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051L-EX

Ground section of compact bone, longitudinal, 40X (osteon=Haversian system, lacunae for osteocytes, canaliculus, Volkmann's canal).

051

Ground section of compact bone, cross, 40X (osteon=Haversian system, lacunae for osteocytes, canaliculus, Volkmann's canal).

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093A Ground section of compact bone, cross, 40X (thinner - good for viewing lacunae and canaliculi).
093B Ground section of compact bone, cross, 40X (osteon=Haversian system, lacunae for osteocytes, canaliculus, Volkmann's canal).
093C Ground section of compact bone, longitudinal, 40X (osteon=Haversian system, lacunae for osteocytes, canaliculus, Volkmann's canal).
   
 
CARDIOVASCULAR SYSTEM

088

Aorta, H&E, 20X (extensive elastin in wall).

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036

Aorta , stained for elastin, 20X (extensive elastin in wall).

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030

Mesentery, H&E, 20X (muscular or medium sized arteries and companion veins, tunica intima, internal elastic lamina, tunica media, tunica adventitia).

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092

Muscular or medium sized artery and companion vein, H&E, 20X.

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092F

Muscular or medium sized artery and companion vein, Masson, 20X.

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095

Small arteries and veins, H&E, 20X.

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095

Small arteries and veins, Masson, 40X.

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040

Trachea, H&E, 40X (small arteries and veins).

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102HE

Heart, ventricle, aortic valve H&E, 40X, (capillaries in heart muscle).

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098-1

Right heart wall, H&E, 40X (heart wall, ventricle, atrium, atrioventricular valve, chorda tendinae [20900 x 52156], capillaries in heart muscle).

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098N

Right heart wall, Masson, 40X (heart wall, ventricle, atrium, atrioventricular valve, capillaries in heart muscle, coronary artery).

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099

Heart, interventricular septum, H&E, 20X (septum, aortic valve, A  V valve, chorda tendinae [16332 x 21928], cardiac skeleton).

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099HM

Heart, interventricular septum, Mallory, 20X (septum, aortic valve, A V valve, chorda tendinae [9861 x 22436], Purkinje fibers [10834 x 1992], cardiac skeleton, atrioventricular bundle of His [41457 x 15106]).

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099M

Heart, interventricular septum, Mallory, 20X (septum, wall of aorta, aortic valve, A V valve, chorda tendinae [12681 x 25921], Purkinje fibers [6706 x 2914], cardiac skeleton [44168 x 13813], atrioventricular bundle of His [42847 x 13351]).

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100

Heart wall and aortic valve, H&E, 20X (ventricle, aortic valve, aorta).

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100

Heart wall and aortic valve, Masson, 40X (ventricle, aortic valve, aorta wall, Purkinje cells [67541 x 59301]).

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100

Heart wall and aortic valve, Aldehyde fuchsin, 20X (ventricle, aortic valve, aorta, elastin stain).

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BLOOD and BONE MARROW

081-2

Human blood smear, Giemsa stain, 40X (red blood cell, neutrophil, lymphocytes, monocytes [43151 x 67377], eosinophils [34777 x 2942, 14930 x 27897], basophil, platelet).

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081-3

Human blood smear, Giemsa stain, 40X (red blood cell, neutrophil, lymphocyte, monocyte, eosinophil [24361 x 19872], basophil, platelet).

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081-4

Human blood smear, Giemsa stain, 40X (red blood cell, neutrophil, lymphocyte, monocyte [38144 x 39508], eosinophil [15012 x 23336, 40295 x 38884], basophil, platelet).

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63x smear Human blood smear, Giemsa stain, 63x scan from hematopathology normals collection Winlab Mac Winhome
86x smear Human blood smear, Giemsa stain, 86x scan from hematopathology normals collection Winlab Mac Winhome

048

Fetal leg, cross section, H&E, 40X (bone marrow in tibia and fibula, developing blood cells, sinusoid [37829 x 41067], megakaryocyte [37861 x 39647, 38143 x 39087, 39555 x 36969, 31707 x 18214]).

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045 Intervertebral disc, H&E, 40X (bone marrow in spongy bone of vertebrae)
   
 
RESPIRATORY SYSTEM

124

Fetal face, frontal section, H&E, 40X (nasal cavity, nasal mucosa, respiratory epithelium, olfactory epithelium [48663 x 10747]).

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124F

Fetal face, horizontal section, H&E, 20X (nasal vestibule, nasal mucosa here is stratified squamous epithelium rather than respiratory epithelium).

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124P

Fetal face, frontal section, H&E, 20X (nasal cavity, nasal mucosa, respiratory epithelium, olfactory epithelium).

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115

Palate, H&E, 20X (respiratory epithelium lining nasal cavity, stratified squamous lining oral cavity).

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126

Trachea and esophagus, H&E, 40X (in trachea: respiratory epithelium, hyaline cartilage, trachealis muscle, glands).

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127

Trachea and esophagus, Masson, 20X (in trachea: respiratory epithelium, hyaline cartilage, trachealis muscle, glands).

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129

Lung, H&E, 20X (bronchus, bronchiole, terminal bronchiole, respiratory bronchiole, alveolar duct, alveolus, pulmonary artery, bronchial artery, pulmonary vein).

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130

Lung, H&E, 20X (bronchus, bronchiole, terminal bronchiole [36024 x 9000], respiratory bronchiole, alveolar duct [21801 x 21141], alveolus, greater alveolar cell = type II pneumocyte [18547 x 9758], macrophage = "dust cell" [26402 x 4353], pulmonary artery, bronchial artery [34857 x 12304], pulmonary vein [24962 x 14668]).

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132

Lung, H&E, 40X (bronchus, bronchiole, terminal bronchiole, respiratory bronchiole, alveolar duct, alveolus, pulmonary artery, bronchial artery, pulmonary vein).

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URINARY SYSTEM

204

Kidney, human, H&E, 40X (cortex, glomerulus, proximal tubule, distal tubule, collecting duct, cortical labyrinth, medullary ray, medulla, vasa recta, loop of Henle, arcuate artery, interlobular arteries and veins).

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210

Kidney, monkey, H&E, 40X (cortex, glomerulus, proximal tubule, distal tubule, collecting duct, cortical labyrinth, medullary ray, medulla, vasa recta, loop of Henle, arcuate artery, interlobular arteries and veins).

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203N

Kidney cortex, human, H&E, 40X

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209

Kidney, monkey, including pelvis, H&E, 20X (medullary pyramid).

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205

Kidney, monkey, vascular injection of red gelatin, counterstained with hematoxylin, 20X (kidney vasculature).

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206

Kidney, human fetus, H&E, 20X (kidney lobes).

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211

Ureter, adult human, H&E, 40X (transitional epithelium, smooth muscle).

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212

Bladder, human, H&E, 40X (transitional epithelium, smooth muscle).

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DIGESTIVE SYSTEM 1: ORAL CAVITY and SALIVARY GLANDS

114

Lip, H&E, 20X (oral mucosa, vermillion border, thin skin, skeletal muscle, small salivary glands, hair follicles, sebaceous glands).

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114M

Lip, H&E, 20X (oral mucosa, vermillion border, thin skin, skeletal muscle, small salivary glands, hair follicles, sebaceous glands).

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115

Palate, H&E, 20X (lip, developing tooth, hard palate, soft palate, oral mucosa [keratinized, non keratinized], respiratory mucosa).

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115

Palate, Masson trichrome, 40X (lip, developing tooth, hard palate, soft palate, oral mucosa [keratinized, non keratinized], respiratory mucosa).

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116

Tongue, H&E, 20X (filiform papillae, fungiform papillae, skeletal muscle).

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117 Tongue, H&E, 20X (circumvalate papilla, trench, taste buds, serous glands [von Ebner], fungiform papillae).

117

Tongue, H&E, 40X (circumvalate papilla, trench, taste buds, serous glands [von Ebner], fungiform papillae).

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122

Tooth and gingiva, Masson trichrome, 20X (crown, root, dentin, pulp cavity, cementum, periodontal membrane, alveolar bone, gingiva [=gum]).

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122

Tooth and gingiva, PAS, 20X (crown, root, dentin, pulp cavity, cementum, periodontal membrane, alveolar bone [=gum]).

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180-1

Parotid gland, H&E, 40X (acini, centroacinar cells, fat cells, striated ducts, intercalated ducts, interlobular ducts).

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180-2

Parotid gland, H&E, 40X (acini, centroacinar cells, fat cells, striated ducts, intercalated ducts, interlobular ducts).

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183-1

Submandibular gland, H&E, 40X (serous acini, mucous acini, striated ducts, intercalated ducts).

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183-2

Submandibular gland, mucicarmine [stains mucus], 20X (serous acini, mucous acini, striated ducts, intercalated ducts).

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184 Submandibular gland, H&E, 20X (serous acini, mucous acini, striated ducts, intercalated ducts).

184

Submandibular gland, H&E, 40X (serous acini, mucous acini, striated ducts, intercalated ducts).

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185-1

Sublingual gland, H&E, 40X (mucous acini, serous acini, striated ducts, intercalated ducts, interlobular ducts).

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185A

Sublingual gland, mucicarmine, 20X (mucous acini, serous acini, striated ducts, intercalated ducts, interlobular ducts).

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DIGESTIVE SYSTEM 2: PHARYNX, ESOPHAGUS, STOMACH

152

Oral pharynx, H&E, 40X (stratified squamous non keratinized epithelium, lamina propria, elastic fibers, muscularis, mucous glands).

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152AF

Oral pharynx, Masson trichrome, 40X (stratified squamous non keratinized epithelium, lamina propria, elastic fibers, muscularis, mucous glands).

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153

Esophagus, H&E, 20X (stratified squamous non keratinized epithelium, lamina propria, muscularis mucosae, submucosa, submucosal mucous glands, muscularis externa [all smooth muscle], myenteric [Auerbach's] plexus).

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155

Esophagus and stomach, H&E, 40X (ESOPHAGUS [at right]: epithelium, lamina propria, muscularis mucosae, submucosa, muscularis externa [all smooth muscle], myenteric [Auerbach's] plexus; CARDIAC STOMACH [next to esophagus, 31875 x 18724]: pits, pyloric glands, muscularis mucosae; FUNDIC STOMACH [at left]: pits, glands, mucous cells, parietal cells [acid], chief cells [pepsinogen], muscularis mucosae, submucosa, muscularis).

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156

Stomach, H&E, 20X ( pits, glands, mucous cells, parietal cells [acid], chief cells [pepsinogen], muscularis mucosae, submucosa, muscularis).

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156

Stomach, H&E, 40X ( pits, glands, mucous cells, parietal cells [acid], chief cells [pepsinogen], muscularis mucosae, submucosa, muscularis).

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157

Stomach, H&E, 20X ( pits, glands, mucous cells, parietal cells [acid], chief cells [pepsinogen], muscularis mucosae, submucosa, muscularis).

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157

Stomach, H&E, 40X ( pits, glands, mucous cells, parietal cells [acid], chief cells [pepsinogen], muscularis mucosae, submucosa, muscularis).

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162

Pyloric stomach [at left], duodenum of small intestine [at right], H&E, 20X (pyloric pits and glands [17152 x 18116]).

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162

Pyloric stomach [at left], duodenum of small intestine [at right], H&E, 40X

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DIGESTIVE SYSTEM 3: SMALL and LARGE INTESTINE

162

Small intestine, duodenum [right side of section], H&E, 40X (villi very poorly preserved, glands [crypts of Lieberkuhn], muscularis mucosae, submucosal glands).

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168

Small intestine, jejunum or ileum, H&E, 20X  (plicae, villi, epithelium, goblet cells, lamina propria, intestinal glands [crypts of Lieberkuhn], Paneth cells, muscularis mucosae, submucosa, muscularis externa, myenteric plexus), serosa).

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168

Small intestine, jejunum or ileum, H&E, 40X (plicae, villi, epithelium, goblet cells, lamina propria, intestinal glands [crypts of Lieberkuhn], Paneth cells, muscularis mucosae, submucosa, muscularis externa, myenteric plexus), serosa).

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169

Small intestine, jejunum or ileum, H&E, 20X  (plicae, villi, epithelium, goblet cells, lamina propria, intestinal glands [crypts of Lieberkuhn], Paneth cells, muscularis mucosae, submucosa, muscularis externa, myenteric plexus), serosa).

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169

Small intestine, jejunum or ileum, H&E, 40X (plicae, villi, epithelium, goblet cells, lamina propria, intestinal glands [crypts of Lieberkuhn], Paneth cells, muscularis mucosae, submucosa, muscularis externa, myenteric plexus), serosa).

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170

Small intestine, ileum, H&E, 20X (Paneth cells [38532 x 9366]).

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170

Small intestine, ileum, H&E, 40X

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171

Small intestine, H&E, blood vessels injected with dye, 20X (observe small blood vessel distribution in villi and elsewhere).

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176

Large intestine (colon), H&E, 20X (straight glands [crypts of Lieberkuhn], no villi, simple columnar epithelium, goblet cells, lamina propria, muscularis mucosae, submucosa, muscularis externa, taenia coli).

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175

Appendix, H&E, 40X (mucosa as in colon, prominent lymphoid nodules in submucosa).

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177-2

Rectoanal junction [anal canal at right], Masson trichrome, 20X (RECTUM: simple columnar epithelium in glands. ANAL CANAL: initially stratified columnar/cuboidal, then stratified squamous epithelium first non keratinized and then keratinized [thin skin, note hair follicles, sebaceous glands], no muscularis mucosae, veins, anal sphincter).

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177-3

Recto anal junction [rectum at far right], H&E, 20X (RECTUM: simple columnar epithelium in glands. ANAL CANAL: initially stratified columnar/cuboidal, then stratified squamous epithelium first non keratinized and then keratinized [thin skin], no muscularis mucosae, veins, anal sphincter).

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DIGESTIVE SYSTEM 4: LIVER and PANCREAS

1

Liver, H&E, 40X (central vein, portal triad [portal vein, bile duct, hepatic artery], hepatocyte, sinus, endothelium, Kupffer cell, "space of Disse", liver lobule).

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194

Liver and gall bladder, H&E, 40X (LIVER: central vein, portal triad [portal vein, bile duct, hepatic artery], hepatocyte, sinus, endothelium, Kupffer cell, "space of Disse", liver lobule. GALL BLADDER: epithelium, lamina propria, muscularis).

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195

Liver and gall bladder, Masson trichrome, 40X (LIVER: distribution of collagen. GALL BLADDER: epithelium, lamina propria, muscularis ).

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198-1

Liver, stained with silver to show bile canaliculi, 20X (try to see 3 dimensional path of bile canaliculi between hepatocytes).

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198

Liver, stained with silver to show bile canaliculi, 40X (bile canaliculi harder to see, because hepatocytes more stained).

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188

Pancreas, H&E, 40X (exocrine pancreas, lobule, acini, centroacinar cell, intercalated duct, endocrine pancreas [islets of Langerhans]).

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189

Pancreas, vascular injection, 40X  (vascular pattern, high vascularity of islets).

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190

Pancreas, chrome alum hematoxylin and phloxine stain, differential staining of cells in islets of Langerhans, 40X (in an islet [20305 x 12114] note that alpha cells [glucagon] have reddish cytoplasm, and beta cells [insulin] have pale blue green cytoplasm; delta cells [somatostatin] can't be distinguished).

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ENDOCRINE SYSTEM

226b

Pituitary gland, human, Masson trichrome, 40X, right side of section is in better focus (pars distalis, acidophils, basophils).

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226

Pituitary gland, human, H&E, 20X (pars distalis [at right], acidophils, basophils, pars nervosa [light area at left]).

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226

Pituitary gland, human, H&E, 40X (pars distalis [at right], acidophils, basophils, pars nervosa [light area at left], pars intermedia [11153 x 12325]).

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227

Pituitary gland, monkey, Masson trichrome, 40X (pars distalis [at right], acidophils, basophils, pars nervosa [light area at left  10440 x 17561], pars intermedia).

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229

Infundibular stalk and hypophyseal portal vessels, H&E, 40X (pars distalis [at left], acidophils, basophils, infundibular stalk [light structure at right], hypophyseal portal vessels [for example, 31695 x 12293]).

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229B

Infundibular stalk and hypophyseal portal vessels, H&E, 20X (pars distalis [at left], acidophils, basophils, infundibular stalk [light structure at right], hypophyseal portal vessels [for example, 17046 x 7025]).

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217

Thyroid gland and parathyroid, H&E, 40X (thyroid, follicles, follicular epithelial cells, colloid, parathyroid [at lower right], chief cells, oxyphil cells [for example, 50605 x 33127]).

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218-1

Thyroid gland, hyperactive, Masson trichrome, 20X (thyroid, follicles [high cuboidal or columnar follicular epithelial cells, little or no colloid], parafollicular cells [=C cells, possible example, 1429 x 4038]).

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218-2

Thyroid gland, hypoactive, Masson trichrome, 20X (thyroid, follicles [flat follicular epithelial cells, abundant colloid], parafollicular cells [=C cells, possible example, 1429 x 4038]).

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220

Parathyroid, H&E, 40X (parathyroid [dense oval in lower part of field], chief cells, oxyphil cells

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230

Adrenal gland, human, H&E, 20X (capsule, cortex, zona glomerulosa, zona fasciculata, zona reticularis, medulla [note that medulla not present in extension at left], branches of central vein).

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231

Adrenal gland, monkey, H&E, 20X (capsule, cortex, zona glomerulosa, zona fasciculata, zona reticularis, medulla, central vein).

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MALE REPRODUCTIVE SYSTEM

270

Testis, human, H&E, 40X (testis [upper left], seminiferous tubules, spermatogonia, primary spermatocytes, secondary spermatocytes [seldom seen, 6499 x 28172], spermatids, Sertoli cells, interstitial tissue, Leydig cells, small blood vessels, tunica albuginea, mediastinum [upper right], rete testis [for example, 59501 x 26604], epididymis [lower half of section], efferent ducts [25621 x 65184]).

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273

Testis, immature human, H&E, 40X (testis, seminiferous tubules with only early germ cells and poorly developed Sertoli cells, small Leydig cells).

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275

Testis, human, H&E, 40X (testis [lower half of section], seminiferous tubules, spermatogonia, primary spermatocytes, spermatids, Sertoli cells, interstitial tissue, Leydig cells, small blood vessels, tunica albuginea, epididymis [upper right], efferent ducts [73044 x 23626]).

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284

Spermatic cord, human, H&E, 20X (ductus or vas deferens [top of section], branch of testicular artery [center of section], pampiniform plexus of testicular veins [around testicular artery branches], dartos muscle [smooth], cremaster muscle [skeletal].

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279

Seminal vesicle, human, H&E, 40X (three lumens of contorted tube, complex interconnecting mucosal folds, secretory epithelium [simple columnar or pseudostratified columnar], lamina propria, abundant smooth muscle in wall of tube).

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281

Prostate, human, H&E, 40X (prostatic urethra [at center], numerous prostatic glands [left, right and middle], secretory epithelium [simple or pseudostratified columnar], abundant smooth muscle in the connective tissue between the glands, two ejaculatory ducts [60183 x 59104, 69144 x 63884] with the prostatic utricle = utriculus masculinus between them.

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282

Prostate, human, H&E, 20X (prostatic glands, with abundant smooth muscle between them, concretions [=amyloid bodies] in many of the glands).

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286

Penis cross section, human, H&E, 40X (two large pale corpora cavernosa [erectile tissue], venous sinuses, trabeculae [connective tissue, smooth muscle, small blood vessels including helicine arteries], deep artery [36102 x 41842], tunica albuginea, penile urethra [at lower right] in corpus spongiosum).

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FEMALE REPRODUCTIVE SYSTEM 1: OVARY and OVIDUCT

239

Ovary, monkey, H&E, 40X (hilus, mesovarium, medulla, cortex, tunica albuginea, primordial follicles [9660 x 7216], ovum, granulosa [follicular] cells, primary follicles [13210 x 4242, 10486 x 6742], secondary follicles [10958 x 4046], antrum, mature [Graafian] follicles [3350 x 4011],theca interna, zona pellucida, cumulus oophorus, corona radiata, atresia [14476 x 6265], glassy membrane, corpus luteum, granulosa lutein cells, theca lutein cells, corpus albicans).

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235

Ovary, H&E, 20X (other examples).

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234-1

Ovary, H&E, 40X (other examples, corpus luteum [57543 x 20061]).

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234-2

Ovary, Masson trichrome, 20X (other examples, corpus luteum [32022 x 16301]).

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236a

Ovary, H&E, 40X (other examples, corpus luteum [57883 x 23061], degenerating corpus luteum [almost a corpus albicans, 69224 x 44462]).

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240-1

Oviduct, H&E, 40X (infundibulum, fimbriae).

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240-2

Oviduct, H&E, 40X (ampulla, ciliated cells, peg cells).

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241

Oviduct, H&E, 40X (isthmus [at left]).

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FEMALE REPRODUCTIVE SYTEM 2: UTERUS, CERVIX, VAGINA

243

Uterus, stage between proliferative and secretory, H&E, 20X (mucosa = endometrium [at right], glands, coiled or spiral arteries [35216 x 9985], myometrium [middle], smooth muscle, perimetrium = connective tissue and serosa [peritoneum] [at left]).

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244

Uterus, proliferative stage, H&E, 40X (another example, coiled or spiral arteries [3480 x 7704]).

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245-1

Uterus, secretory stage, H&E, 40X (endometrium with secretory glands, coiled or spiral arteries [36411 x 42546]).

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245-2

Uterus, menstrual stage, H&E 40X (st. functionalis sloughing off, heavy lymphocytic infiltration).

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249

Cervix, H&E, 20X (cervical glands [below] with columnar epithelium [secretes mucus], muscle [above], uterine wall [at left], vagina [at right]).

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250-1

Vagina, H&E, 40X (stratified squamous epithelium non keratinized, connective tissue, smooth muscle [inner circular, outer longitudinal]).

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250-2

Vagina, Masson trichrome, 40X (another example, distribution of connective tissue [blue] and smooth muscle [reddish] seen particularly well, many nerves).

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FEMALE REPRODUCTIVE SYSTEM 3: PLACENTA and MAMMARY GLAND

255

Placenta, late, H&E, 20X (villi).

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255

Placenta, late, H&E, 40X (villi, maternal blood space, syncytiotrophoblast, occasional cytotrophoblast [15841 x 54474],capillary, macrophage [Hofbauer cell, 19857 x 49500]), fibrinoid).

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259

Mammary gland, inactive = nulliparous, H&E, 20X (glandular lobules [38427 x 9571], ducts, myoepithelial cells, intralobular and interlobular connective tissue).

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258

Mammary gland, active [perhaps middle of pregnancy], H&E, 20X (alveoli, myoepithelium, plasma cells, ducts,lactiferous ducts).

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261

Mammary gland, active, H&E, 40X (another example).

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265

Nipple and areola, H&E, 20X (nipple [center], areola [at left and right], lactiferous ducts, myoepithelial cells, thin skin, sebaceous glands, smooth muscle strands, nerves).

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LYMPHATIC SYSTEM

26

Lymph node, H&E, 20X (lymph node at upper right, see next).

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26

Lymph node, H&E, 40X (detail of above, capsule, afferent lymphatic vessels, subcapsular sinus, cortex, follicles=nodules [mostly B cells], germinal centers [abnormal here, see slide 30], parafollicular cortex=deep cortex [mostly T cells], high endothelial venules [18168 x 11003], medulla, cords, sinuses, endothelial cells [27879 x 9242], reticular cells [31169 x 10376], macrophages, hilus).

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30

Lymph node [in mesentery see dark structures], H&E, 20X (see 26 40X above for structures, follicular germinal center [4403 x 9926], high endothelial venules [5185 x 11780]).

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142

Lymph node, H&E, 40X (see 26 40X above for structures, germinal centers [19321 x 4340], high endothelial venules [37748 x 13915]).

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27

Lymph node, H&E, 40X (see 26 40X above for structures, germinal centers [2352 x 18432]).

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28-2

Lymph node, stained with silver to show reticular fibers [black], 40X (reticular fibers are made by reticular cells [6978 x 6510]).

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138

Tonsil, palatine, H&E, 20 (crypt [white space beginning at top and extending down], crypt lined with stratified squamous epithelium non keritanized [seen at 7730 x 1589, but mostly out of focus elsewhere], lymphatic follicles with large germinal centers).

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138

Tonsil, palatine, H&E, 40 (detail of previous, macrophage [antigen presenting cell, 17193 x 27388]).

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138L

Tonsil, faucial, H&E, 40X (several crypts lined with stratified squamous epithelium non keritanized, lymphoid follicles).

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147B

Spleen, H&E, 40X (capsule, trabeculae [dense c.t., stains red], white pulp, central arterie w/ periarteriolar lymphatic sheath=PALS [mostly T cells], lymphatic follicles [mostly B cells, sometimes with germinal center], marginal zone, red pulp, splenic cords, venous sinuses, reticular cells [2939 x 15393]).

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148

Spleen, H&E, 20X (see 147 20X above for structures).

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148

Spleen, H&E, 40X (detail of previous, red pulp sinuses [4241 x 12157, 4107 x 10331]).

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301

Spleen, H&E, 40X (see 147 20X above for structures, central artery [16535 x 10481, with PALS and lymphatic follicle with large germinal center]).

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140

Thymus, young, H&E, 40X (cortex [darker, developing T cells], medulla [lighter], epithelial reticular cells, macrophages, Hassall's corpuscles.

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141

Thymus, adult, 40X (extensive fatty tissue, cortex and medulla quite involuted).

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CENTRAL NERVOUS SYSTEM

65-1

Spinal cord and dorsal root ganglion, H&E, 20X (white matter [pinkish], gray matter [grayish], dorsal horn, ventral horn, ventral horn cells [large motor neuron cell bodies], neuropil,dorsal root ganglion [at right], sensory neurons,capsular cells, sensory axon tracts).

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65-2

Spinal cord and dorsal root ganglion, H&W, 20X (see above for structures, the section is upside down [dorsal is downward] and much of it is out of focus, there are dorsal root ganglia at both right and left).

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77

Cerebellum, H&E, 20X (white matter [pink, lower center and upward], gray matter [molecular layer, Purkinje cells, granular layer]).

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77

Cerebellum, H&E, 40X (detail of previous slide, molecular layer [small axons give input to Purkinje dentrites], Purkinje cell bodies [very large, extensive dendritic trees not visible, axons go through granular layer to white matter], granular layer [dark layer, granule cells].

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76

Cerebrum, axons and neuron cell bodies stained blue, 40X (white matter [stained dark blue], cerebral cortex, pyramidal cells, pyramid shaped neuron cell bodies of various size, dendritic tree not visible, axon goes to white matter], glial cells, sulcus [white line from top to bottom of this section] between gyri.

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EYE

EYE-2

Eyeball, H&E, 20X

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EYE-1

Posterior eye (retina), H&E, 20X

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EAR
EAR-1 Inner ear, 40X (cochlea [scala vestibuli, vestibular membrane=Reissner's membrane, cochlear duct, stria vascularis, basilar membrane, scala tympani, modiolus, helicotrema], organ of Corti [outer hair cells, phalangeal cells, reticular lamina, outer and inner tunnels and pillar cells, inner hair cells, tectorial membrane], nerves [spiral ganglion, auditory branch of 8th nerve], vestibule [bony labyrinth], utricle and saccule [membranous labyrinth], macula [hair cells, supporting cells, otolithic membrane, otoliths=otoconia]. Not shown here are semicircular canals, ampullae, cristae [hair cells, supporting cells, cupula]).
EAR-2 Inner ear, 40X
EAR-3 Inner ear, 40X (see above for structures, macula [22175 x 26545]).

Produced by The Learning Resource Center - Office of Medical Education
© copyright 2005-08 The Regents Of The University Of Michigan. All rights reserved.

QUESTIONS or COMMENTS? E-mail Dr. J. Matthew Velkey (jvelkey@med.umich.edu)