Links

 

Publications

 

View my collection, "My Bibliography" from NCBI

1. Udvadia, A.J., Rogers, K.T., Higgins, P.D.R., Murata, Y., Martin, K.H., Humphrey, P.A., Horowitz, J.M. Sp-1 binds promoter elements regulated by the RB protein and Sp-1 mediated transcription is stimulated by RB coexpression. Proceedings of the National Academy of Sciences USA 1993; 90:3265-3269.

2. Rogers, K.T.*, Higgins, P.D.R.*, Milla, M.M., Phillips, R.S., and Horowitz, J.H. DP-2, a heterodimeric partner of E2F:  Identification and characterization of DP-2 proteins expressed in vivo. Proceedings of the National Academy of SciencesUSA 1996; 93: 7594-7599.

3. Higgins, P.D.R. and Askari, FK. Barrett's Esophagus: Diagnosis and Therapy. The National Organization of Rare Diseases Guide to Rare Diseases, 2001, Lippincott.

4. Higgins, P.D.R., Russo, C.A., Scheurer, M., Duvall, W.L. How Well do we Treat Elevated Lipids? North Carolina Medical Journal 2002; 63: 247-52.

5. Higgins, P.D.R., and Fontana, R. Transplantation and Acute Liver Failure. Panminerva Medica 2003; 45: 85-94.

6. Higgins, P.D.R., and Rockey, D.C. Iron Deficiency Anemia. Techniques in Gastrointestinal Endoscopy 2003; 5: 134-141.

7. Higgins, P.D.R., and Laine, L. Ischemic Colitis: A Systematic Review. Alimentary Pharmacology and Therapeutics 2004; 19:729-38.

8. Higgins, P.D.R., and Johanson, J. A Systematic Review of the Epidemiology of Constipation. American Journal of Gastroenterology 2004; 99: 750-759.

9.Higgins, P.D.R., and Zimmermann, E.M. Inflammatory Bowel Disease Diagnosis and Therapy. Clinics in Family Practice 2004; 6: 671-692.

10. Higgins, P.D.R., Schwartz, M., Mapili, J., and Zimmermann, E.M. Is Endoscopy Necessary for the Measurement of Disease Activity in Ulcerative Colitis? American Journal of Gastroenterology 2005; 100:355-361.

11. Higgins, P.D.R., Schwartz, M., Mapili, J., and Zimmermann, E.M. Defining Patient-Centered Remission in Common Disease Activity Indices in Ulcerative Colitis. Gut 2005; 54: 782-788.

12. Poynter, J.N., Gruber, S.B., Higgins, P.D.R., Almog, R., Bonner, J.D., Rennert, H.S., Low, M., Greenson, J.K., and Rennert, G. Statins and the Risk of Colorectal Cancer. New England Journal of Medicine 2005; 352: 2184-2192.

13. Higgins, P.D.R., Umar, R. Parker, J.W., and DiMagno, M. Massive Lower Gastrointestinal Bleeding after Rejection of Pancreatic Transplants. Nature Clinical Practice Gastroenterology and Hepatology, 2005; 2: 240-244.

14. Harris, Richard E., Jeter, Joanne, Chan, Paul, Higgins, P.D.R., Kong, Feng-Ming, Fazel, Reza, Bramson, Candace, Gillespie, Brenda, and Cohort 11 of the UM CRDSA. Using Accupressure to Modify Alertness in the Classroom: A Single-Blind, Randomized, Crossover Trial. The Journal of Alternative and Complementary Medicine. 2005; 11: 673-679.

15. Demierre, Marie-France*, Higgins, P.D.R.*, Gruber, Stephen B., Hawk, Ernest, and Lippmann, Scott. Statins and Cancer Prevention, Nature Reviews Cancer, 2005; 5: 930-942.

16. Waljee, A. and Higgins, P.D.R. Statins Reduce Inflammation, DVT, Osteoporosis, and Colon Cancer: Could they Be of Benefit in IBD? Practical Gastroenterology, 2006; 30: 34-46.

17. Waljee, A. Waljee, J., Morris, A., and Higgins, P.D.R. Three-Fold Increased Risk of Infertility: A Meta-Analysis of Infertility after Ileal Pouch Anal Anastomosis in Ulcerative Colitis. Gut, 2006; 55: 1575-80.

18. Bhuket, T.P., and Higgins, P.D.R. Statins and Gastrointestinal Cancer. Nature Clinical Practice Gastroenterology and Hepatology, 2006; 3:  552-562.

19. Menees, S., Higgins, P.D.R., Korsnes, S, Elta, G. Does Colonoscopy Preparation Cause a Flare of Ulcerative Colitis Symptoms? Inflammatory Bowel Diseases, 2007; 13: 12-18.

20. Higgins, P.D.R., Caoili, E., Zimmermann, M., Bhuket, T. P., Sonda, P., Manoogian, B., Platt, J., and Zimmermann, E.M. Computed Tomographic Enterography (CTE) Adds Information to Clinical Management in Small Bowel Crohns Disease, Inflammatory Bowel Diseases, 2007; 13: 262-268.

21. Higgins, P.D.R., Leung, J., Schwartz, M., Mapili, J., Wren, P.A., Zimmermann, E.M. The Quantitative Validation of Non-Endoscopic Disease Activity Indices in Ulcerative Colitis, Alimentary Pharmacology and Therapeutics, 2007; 25(3):333-42.

22. Higgins, P.D.R., Katz, S., Wolf, D.C., and Present, D.H. Clinical Trial Designs in Ulcerative Colitis. Gastroenterology and Hepatology, 2007; 3 S10: 1-7.

23. Bandarenko, N., and Higgins, P.D.R. Treatment of Inflammatory Bowel Disease:  An Overview of Pharmacologics, Biologics, and Selective Leukocyte Apheresis. CME Monograph. MediCine, Inc., New York, NY. June, 2007.

24. Awais, D., and Higgins, P.D.R. Should we be CHARMed?, Inflammatory Bowel Diseases, 2007 Oct;13:1308-9.

25. Elmunzer, J., Higgins, P.D.R., Kwok, Y., and Elta, G. Jumbo forceps are superior to standard large-capacity forceps in obtaining diagnostically adequate inflammatory bowel disease surveillance biopsies. Gastrointestinal Endoscopy, 2008; 68: 273-8.

26. Kim, K., Rangwalla, S., Congxian, J., Higgins, P.D.R., and Rubin, J. Non-Invasive Ultrasound Elasticity Imaging (UEI) On Crohn's Disease: Animal Model. Ultrasound in Medicine and Biology, 2008; 34: 902-12.

27. Elmunzer, B.J., Waljee, A.K., Elta, G.H., Taylor, J.R., Fehmi, S.M.A., Higgins, P.D.R. A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis. Gut, 2008; 57:1262-7.

28. Bruce E. Sands, William J. Sandborn, Brian Feagan, Robert Lofberg, Toshifumi Hibi, Tao Wang, Lisa Marie Gustofson, Cindy J. Wong, Margaret K. Vandervoort, Stephen Hanauer, and the Adacolumn Study Group. A Randomized, Double-Blind, Sham-Controlled Study of Granulocyte/Monocyte Apheresis for Active Ulcerative Colitis. Gastroenterology, 2008; 135: 400-409.

29. Stenson, W.F., Snapper, Scott B., and the CCFA Research Challenges Work Groups. Challenges in IBD Research: Assessing Progress and Rethinking the Research Agenda. Inflammatory Bowel Diseases, 2008; 14: 687-708.

30. Ho, W., Melmed, G., Targan, S., Dubinsky, M., Esrailian, E., Siegel, C., Higgins, P.D.R., Spiegel, B. Controversies in Ulcerative Colitis: A National Survey Comparing Decision-Making of Experts versus Community Gastroenterologists. Clinical Gastroenterology and Hepatology, 200, 7: 168-174.

31. Joyce, J.C., Waljee, A.K., Khan, T.A., Wren, P.A., Dave, M., Zimmermann, E.M., Wang, S., Zhu, J., Higgins, P.D.R. Identification of Symptom Domains in Ulcerative Colitis that Occur Frequently During Flares and are Responsive to Changes in Disease Activity. Health and Quality of Life Outcomes 2008, 6:69.

32. Irvine, E.J., Yeh, C-H, Ramsey, D., Stirling, A.L., Higgins, P.D.R. The effect of mesalamine therapy on quality of life in patients with mildly to moderately active ulcerative colitis. Alimentary Pharmacology and Therapeutics. 2008, 28: 1278-86.

33. Rangwalla, S.R., Waljee, A.K., Higgins, P.D.R. The Voting With their Feet (VWF) Endpoint: A Meta-Analysis of an Alternative Endpoint in Clinical Trials, Using 5-ASA Induction Studies in Ulcerative Colitis. Inflammatory Bowel Diseases, 2009, 15(3): 422-8.

34. Higgins, P.D.R., Rubin, D.T., Kaulback, K., Schoenfeld, P.S., Kane, S.V. Systematic Review: Impact of Non-Adherence to 5-ASA Products on the Frequency and Cost of Ulcerative Colitis Flares. Alimentary Pharmacology and Therapeutics. 2009, 29: 247-57.

35. Kane S, Lu F, Kornbluth A, Awais D, Higgins P.D.R. Controversies in mucosal healing in ulcerative colitis. Inflammatory Bowel Diseases, 2009, 15: 796-800.

36. Waljee, A.K., Joyce, J.C., Wren, P.A., Khan, T.M., Higgins, P.D.R. Patient reported symptoms during an ulcerative colitis flare:  A Qualitative Focus Group Study. European Journal of Gastroenterology & Hepatology. 2009, 21: 558-64.

37. Singal A, Volk ML, Waljee A, Salgia R, Higgins P.D.R., Rogers MA, Marrero JA. Meta Analysis: Surveillance with Ultrasound for Early Stage Hepatocellular Carcinoma in Patients with Cirrhosis. Alimentary Pharmacology and Therapeutics. 2009, 30: 37-47.

38. Rubenstein, J.H., Waljee,  A.K., Jeter, J., Velayos, F., Ladabaum, U., Higgins, P.D.R. Cost-Effectiveness of Ulcerative Colitis Surveillance in the Setting of 5-Aminosalicylates. American Journal of Gastroenterology, 2009, in press.

39. Adler, J., Stidham, R.J., Higgins, P.D.R. Bringing the Inflamed and Fibrotic Bowel into Focus: Imaging in Inflammatory Bowel Disease. Gastroenterology and Hepatology, 2009; 5: 1-11.

40. Awais, D., Seigel, C.A., Higgins, P.D.R., Modeling Dysplasia Detection in Ulcerative Colitis: Clinical Implications of Surveillance Intensity. Gut. 2009, 58: 1498-1503. PDF

41. Luther, J., Higgins, P.D.R., Schoenfeld, P., Moayyedi, P., Vakil, N., Chey, W. Empiric Quadruple vs. Triple Therapy for Primary Treatment of Helicobacter pylori Infection: Systematic Review and Meta-Analysis of Efficacy and Tolerability. American Journal of Gastroenterology, 2010, 105: 65-73.

42. Waljee, A.K., Joyce, J.C., Wang, S., Saxena, A., Hart, M., Zhu, J., Higgins, P.D.R. Machine Learning Outperforms Metabolites in Identifying Responders to Thiopurines in Inflammatory Bowel Disease. Clinical Gastroenterology and Hepatology, 2010; 8: 143-150.

43. Luther, J., Dave, M., Higgins, P.D.R., Kao, J.Y. Association Between Helicobacter pylori Infection and Inflammatory Bowel Disease: A Meta-analysis and Systematic Review of the Literature. Inflammatory Bowel Diseases, 2010, in press.

44. Stidham, R.J., Waljee, A.K., Higgins, P.D.R. Evolving Endpoints in IBD Management. IBD Monitor, 2010, in press.

45. Waljee, A.K., Joyce, J.C., Wang, S., Saxena, A., Hart, M., Zhu, J., Higgins, P.D.R. Machine Learning Outperforms Metabolites in Identifying Responders to Thiopurines in Inflammatory Bowel Disease. Clinical Gastroenterology and Hepatology, 2010, in press. PDF

46. Adler, J, Higgins PDR. Getting the Steak without the Sizzle: Is MR enterography as good as CT Enterography? Inflammatory Bowel Diseases, 2010, in press.

47. Dave, M., Elmunzer, B.J., Dwamena, B.A., Higgins, P.D.R. Primary Sclerosing Cholangitis: A meta-analysis of diagnostic performance of Magnetic Resonance Cholangiopancreatography. Radiology, 2010, in press.

48. Huang, E.H., Johnson, L.A., Eaton, K., Hynes, M.J., Carpentino, J.E., Higgins, P.D.R. Atorvastatin Induces Apoptosis in Vitro And Slows Growth Of Tumor Xenografts But Not Polyp Formation In Min Mice. Digestive Diseases and Sciences, 2010, in press.

49. Higgins, P.D.R., Book Review: The Changing World of Inflammatory Bowel Disease, Gastroenterology, 2010, in press.

50. Stidham, R.W., Higgins, P.D.R. The Value of Mucosal Assessment and Biomarkers in Inflammatory Bowel Disease. Expert Review of Gastroenterology & Hepatology, 2010; 4(3):285-91.

51. Waljee, A.K., Higgins, P.D.R. Machine Learning in Medicine: A primer for physicians. American Journal of Gastroenterology, 2010; 105(6):1224-6.

52. Govani, S., Higgins, P.D.R., Combination of Thiopurines and Allopurinol: Adverse Events and Clinical Benefit in IBD. Journal of Crohn’s and Colitis, 2010, in press.

53. Higgins, P.D.R. New Keys to Maintenance Treatment in Ulcerative Colitis. Digestive Diseases, 2010, in press.

54. Higgins, P.D.R., Johnson, L.A., Luther, J., Zhang, M., Kao, J.Y. Prior H. pylori infection ameliorates S. typhimurium induced colitis: mucosal crosstalk between stomach and distal intestine. Inflammatory Bowel Diseases, 2011, in press.

55. Waljee, A.K., Morris, A.M., Waljee, J.F.,  Higgins, P.D.R., Individual Health Discount Rate in Patients with Ulcerative Colitis. Inflammatory Bowel Diseases, 2011, in press.

56. Dave, M., Johnson, L.A., Walk, S., Young, V.B., Stidham, R.W., Chaudhary, M.N., FunNell, J., Higgins, P.D.R. A Randomized Trial of Sheathed vs. Standard Forceps for Obtaining Uncontaminated Biopsy Specimens of Microbiota from the Terminal Ileum. Gut, 2011, in press.

57. Higgins, P.D.R., Johnson, L.A., Sauder, K., Moons, D., Blanco, L.P., Taube, S., Wobus, C.E., Transient or Persistent Norovirus Infection Does Not Alter the Pathology of Salmonella typhimurium Induced Intestinal Inflammation and Fibrosis in Mice. Comparative Microbiology, Immunology and Infectious Diseases, 2011, in press.

58. D'Haens GR, Panaccione R, Higgins PDR, Vermeire S, Gassull M, Chowers Y, Hanauer SB, Herfarth H, Hommes DW, Kamm M, Löfberg R, Quary A, Sands B, Sood A, Watermayer G, Lashner B, Lémann M, Plevy S, Reinisch W, Schreiber S, Siegel C, Targan S, Watanabe M, Feagan B, Sandborn WJ, Colombel JF, Travis S. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: When to Start, When to Stop, Which Drug to Choose, and How to Predict Response? American Journal of Gastroenterology, 2011, 106: 199-212.

59. Waljee AK, Morris AM, Waljee JF, Higgins, PDR. Perceived and actual quality of life with ulcerative colitis: a comparison of medically and surgically treated patients. American Journal of Gastroenterology, 2011, 106:794-799.

60. Adler, J, Rangwalla, SC, Dwamena, BA, Higgins, PDR. The Prognostic Power of the NOD2 Genotype for Compicated Crohn's Disease: A Meta-Analysis. American Journal of Gastroenterology, 2011, 106: 699-712.

61. Adler J, Swanson SD, Schmiedlin-Ren P, Higgins PDR, Golembeski CP, Polydorides AD, McKenna BJ, Hussain HK, Verrot TM, Zimmermann EM. Magnetization Transfer Helps Detect Intestinal Fibrosis in an Animal Model of Crohn's Disease. Radiology, 2011, 259:127-135.

62. Higgins, PDR, Johnson LA, Sauder K, Moons D, Blanco L, Taube S, Wobus, CE. Transient or Persistent Norovirus Infection Does not Alter the Pathology of Salmonella typhimurium induced intestinal inflammation and fibrosis in mice. Comp Immunol Microbiol Infect Dis, 2011, 2011, 34: 247-257.

63. Higgins, PDR. Who Wants to Take a Thiopurine Holiday? American Journal of Gastroenterology, 2011, 106: 556-558.

64. Travis SP, Higgins P.D.R., Orchard T, Van Der Woude CJ, Panaccione R, Bitton A, O'Morain C, Panes J, Sturm A, Reinisch W, Kamm MA, D'Haens G. Review article: defining remission in ulcerative colitis. Alimentary Pharmacology and Therapeutics. 2011. 34: 113-24. Review.

65. Johnson, L.A., Luke, A., Sauder, K., Moons, D.S., Horowitz, J.C., Higgins, P.D.R. Intestinal Fibrosis is Reduced by Early Elimination in a Mouse Model of IBD: Impact of a "Top-Down" Approach to Intestinal Fibrosis in Mice. Inflammatory Bowel Diseases, 2011, in press. PDF

66. Stidham, R.W., Xu, J., Johnson, L.A., Kim, K., Moons, D.S., McKenna, B., Rubin, J.M., Higgins, P.D.R. Ultrasound Elasticity Imaging for Detecting Intestinal Fibrosis and Inflammation in Rats and Humans with Crohn's Disease. Gastroenterology, 2011, 141(3):819-826.

67. Brown, L.K., Waljee, A.K., Higgins, P.D.R., Waljee, J.F., Morris, A.M. Proximity to disease and perception of utility: Physicians' vs. patients' assessment of treatment options for ulcerative colitis. Diseases of the Colon and Rectum. 2011, 54: 1529-36.

68. Johnson, L.A., Govani, S.M., Joyce, J.C., Waljee, A.K., Gillespie, B.W., Higgins, P.D.R., Spironolactone and colitis: Increased mortality in rodents and humans. Inflammatory Bowel Diseases, 2011, 54: 1529-36. .

69. Horowitz, JC, Ajayi, IO, Kulasekaran, P, Rogers, DS, White, JB, Townsend, SK, White, ES, Nho RS, Higgins, P.D.R., Huang, SK, Sisson, TH. Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis. Int J Biochem Cell Biol., 2012, 44:158-169. PMCID: PMC3241828

70. Xu, J., Tripathy, S., Rubin, J.M., Stidham, R.W., Johnson, L.A., Higgins, P.D.R., and Kim, K. A New Nonlinear Parameter in the Developed Strain-To-Applied Strain of the Soft Tissues and Its Application in Ultrasound Elasticity Imaging. Ultrasound in Medicine and Biology, 2012; 38: 511-23.

71. Elmunzer, B.J., Scheiman, J.M, Lehman, G.A., Chak, A., Mosler, P., Higgins, P.D.R., Hayward, R.A., Romagnuolo, J., Elta, G.H., Sherman, S., Waljee, A.K., Repaka, A., Atkinson, M., Cote, G.A., Kwon, R.S., McHenry, L., Piraka, C., Wamsteker, E.J., Watkins, J.L., Korsnes, S.J., Schmidt. S.E., Turner, S.M., Nicholson, S., Fogel, E.L.  on behalf of the United States Cooperative for Outcomes Research in Endoscopy (USCORE). A Randomized Trial of Rectal Indomethacin to Prevent Post-ERCP Pancreatitis. New England Journal of Medicine, 2012; 366: 1414-22. PMCID: PMC3339271

72. Govani, S.M., Higgins, P.D.R. How to Read a Clinical Trial Paper: A Lesson in Basic Trial Statistics. Gastroenterology & Hepatology, 2012; 8: 241-248. PMCID: PMC3380258

73. Katz, L, Gisbert, JP, Manoogian, B, Lin, K, Steenholdt, C, Mantzaris, GJ, Atreja, A., Ron, Y, Swaminath, A, Shah, S, Hart, A, Lakatos, PL, Ellul P, Israeli, E, Svendsen, MN, van der Woude, CJ, Katsanos, KH, Yun, L, Tsianos, EV, Nathan, T, Abreu, M, Dotan, I, Lashner, B, Brynskov, J, Terdiman, JP, Higgins, P.D.R., Chaparro, M, Ben-Horin, S. Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response. Inflammatory Bowel Diseases, 2012, in press.

73. Reider, F., Karrasch, T. Ben-Horin, S., Schirebel, A., Ehehalt, R., Wehkamp, J., de Haar, C., Velin, D., Latella, G., Scaldaferri, F., Rogler, G., Higgins, P.D.R., Sans, M. Results of the 2nd Scientific Workshop of the ECCO: Basic Mechanisms of Intestinal Healing. Journal of Crohn's and Colitis, 2012; 6: 373-385.

74. Peyrin-Biroulet, L., Billoud, V., D'Haens, G., Panaccione, R., Feagan, B., Panes, J., Danese, S., Schreiber, S., Ogata, H., Hibi, T., Higgins, P.D.R., Beaugerie, L., Chowers, Y., Louis, E., Steinwurz, F., Reinisch, W., Rutgeerts, P., Colombel, J.F., Travis, S., Sandborn, W.J. Development of the Paris Definition of Early Crohn's Disease for Disease-Modification Trials: Results of an International Expert Opinion Process. American Journal of Gastroenterology, 2012, in press.

75. Johnson, L.A., Sauder, K.L., Rodansky, E.S., Simpson, R.U., Higgins, P.D.R., CARD-024, A Vitamin D Analog, Attenuates the Pro-fibrotic Response to Substrate Stiffness in Colonic Myofibroblasts. Experimental and Molecular Pathology, 2012; 93: 91-98.

76. Saini, SD, Waljee, AK, Higgins, P.D.R. Cost-Utility of Inflammation-Targeted Therapy In Ulcerative Colitis. Clinical Gastroenterology and Hepatology, 2012, in press.

77. Stidham, RW, Sauder, K, Higgins, P.D.R. Using Bibliometrics to Advance Your Academic Career. Gastroenterology, 2012, in press.

78. Dave, Maneesh, Higgins, P.D.R. , Rioux, Kevin. The Human Gut Microbiome: Current Knowledge, Challenges, and Future Directions. Translational Research, 2012, in press.

79. Hueber, W., Sands, B.E., Lewitzky, S., Vandemeulebroecke, M., Reinisch, W., Higgins, P.D.R. , Wehkamp, J., Feagan, B.G., Yao, M.D., Karczewski, M., Karczewski, J., Pezous, N., Bek, S., Bruin, G., Mellgard, B., Berger, C., Londei, M., Bertolino, A.P., Tougas, G., Travis, S.P.L. Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial. Gut, 2012, in press.

80. Sisson, T.H., Maher, T., Ajayi, I.O., King, J.E., Higgins, P.D.R., Booth, A.J., Sagana, R.L., Huang, S.K., White, E.S., Moore, B.M., Horowitz, J.C. Increased Survivin Expression Contributes to Apoptosis-resistance in IPF Fibroblasts. Advances in Bioscience and Biotechnology, 2012, in press.

81. Johnson, L.A., Rodansky, E., Sauder, K., Horowitz, J.C., Mih, J., Tschumperlin, D.A. Matrix Stiffness Corresponding to Strictured Bowel Induces a Fibrogenic Response in Human Colonic Fibroblasts. Inflammatory Bowel Diseases, 2012, in press.

82. Denson, L.A., Long, M.D., McGovern, D.P.B., Kugathasan, S., Wu, G.D., Young, V.B., Pizarro, T.T., de Zoeten, E.F., Stappenbeck, T.S., Plevy, S.E., Abraham, C., Nusrat, A., Jobin, C., McCole, D.F., Siegel, C.A., Higgins P.D.R., Herfarth, H.H., Hyams, J., Sandborn, W.J., Loftus, E.V., Kappelman, M.D., Lewis, J.D., Parkos, C.A., Sartor, R.B., Challenges in IBD Research: Update on Progress and Prioritization of the CCFA's Research Agenda. Inflamm Bowel Dis, 2012, in press.

83. Govani, S.M., Stidham, R.W., Higgins, P.D.R. How Early to Take Arms Against a Sea of Troubles? The Case for Aggressive Early Therapy in Crohn’s Disease to Prevent Fibrotic Intestinal Strictures. Journal of Crohn’s and Colitis, 2013, in press.

84. Waljee, A.K., Mukherjee, A., Singal, A.G., Zhang, Y., Warren, J., Balis, U., Marrero, J., Zhu, J., Higgins, P.D.R. Comparison of Modern Imputation Methods for Missing Laboratory Data in Medicine. BMJOpen, 2013, in press.

85. Magro, F., Peyrin-Biroulet, L., Sokol, H., Aldeger, X., Costa, A., Higgins, P.D.R., Joyce, J.C., Kastanos, K.H., Lopez, A., Mas de Xaxars, T., Toader, E., Beaugerie, L. Extraintestinal malignancies in inflammatory bowel disease: Results of the 3rd ECCO Pathogenesis Scientific Workshop (III). Journal of Crohn’s and Colitis, 2013, in press.

86. Sands, B.E., Katz, S., Wolf, D.C., Feagan, B.G., Wang, T., Gustofson, L.M., Wong, C.J., Vandervoort, M.K., Hanauer, S. and the Adacolumn Study Group. A Randomized, Double-Blind, Sham-Controlled Study of Granulocyte/Monocyte Apheresis for Moderate to Severe Crohn’s Disease. Gut, 2013; 62: 1288-1294. [P.D.R. Higgins – I participated in this study as a site PI, and I am cited in the publication].

87. Vavricka, S.R., Rogler, G., Maetzler, S., Misselwitz, B., Safroneeva, E., Frei, P., Manser, C.N., Biedermann, L., Fried, M., Higgins, P.D.R., Wojtal, K.A., Schoepfer, A.M. High Altitude Journeys and Flights are Associated with An Increased Risk of Flares in Inflammatory Bowel Disease Patients. Journal of Crohn’s and Colitis, 2013, in press.

88. Waljee, A.K., Stidham, R., Higgins, P.D.R., Vijan, S., Saini, S.D. Point-Counterpoint: Are we Overtreating Patients with Mild Ulcerative Colitis? Journal of Crohn’s and Colitis, 2013, in press.