The main objective of the Liver Disease Blood and Tissue Repository is to facilitate clinical and translational research. The repository of blood samples (plasma and serum) and liver tissue samples will be utilized by clinical and translational researchers to answer questions related to the pathophysiology and clinical outcomes of chronic liver disease. The samples will be used to evaluate the utility of available markers for the diagnosis and prognosis of various liver diseases including fatty liver, viral hepatitis, and liver cancer, and to discover new biomarkers such as biomarkers for liver fibrosis and liver cancer. We hope these studies will help us to better predict disease severity and progression of chronic liver disease and guide the management of patients in the future.
The rapid development of genomics, proteomics, and metabolomics have significantly increased the potential for productive translational research in transplantation, and many current research protocols in solid organ transplantation utilize blood and urinary specimens, in an effort to establish relationships between biologic markers, histological findings, and clinical outcomes. The main objective of the Liver Disease Blood and Tissue Repository is to facilitate clinical and translational research to utilize blood, cells and urine from patients who are candidates or have received a transplanted liver along with relevant medical record information to study clinical outcome and to discover new pathways and biomarkers to predict disease progression and guide future management.
For full inclusion and exclusion criteria, please contact the research staff.