Non-Alcoholic Steatohepatitis (NASH)


A phase 2b, dose-ranging, randomized, double-blind, placebo-controlled trial evaluating the safety and efficacy of GS-6624, a monoclonal antibody against lysyl oxidase-like 2 (LOXL2), in subjects with advanced liver fibrosis but not cirrhosis secondary to non-alcoholic steatohepatitis (NASH)

Enrollment status: OPEN

Objective

To determine if injectable study drug (simtuzumab, GS-6624) is effective at preventing the progression of liver fibrosis in subjects with non-cirrhotic NASH

Inclusion criteria

Exclusion Criteria

Study Design


Contacts for referrals or questions:

Principal investigator: Robert Fontana, MD rfontana@med.umich.edu