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Irritable Bowel Syndrome (IBS)

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Comparing two forms of dietary therapy to control the symptoms of irritable bowel syndrome with diarrhea (IBS-D): a randomized, controlled trial and gastrointestinal microbiome analysis

IRB# HUM00053274


The study compares two diets that have been recommended for improving symptoms associated with IBS.


The study is seeking adults with irritable bowel syndrome with diarrhea (IBS-D) whose abdominal discomfort and diarrhea are not well controlled. After a 2-week screening period, during which the severity of symptoms will be assessed and eligibility determined, patients will be randomized to receive one of two diets: Diet 1 or Diet 2, to which they will adhere for 4 weeks. In addition, stool and blood samples will be collected before and after randomization to measure relevant biomarkers.

Subject Eligibility

Compensation: $120

Expected Recruitment End Date: January 2014

Principal Investigator: Shanti Eswaran, MD

Study Coordinator: Lina E-mail:, Telephone: (734) 936-2761