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Nathan Shock Center of Excellence for the Basic Biology of Aging

Funded by the NIA, the Nathan Shock Center enhances and encourages multidisciplinary research in the basic biology of aging at U-M and worldwide. Visit the Shock web site at

Research Areas:

Genetic control of aging, aging and immunity, animal models of aging, discovery of anti-aging drugs, and musculoskeletal frailty.

Director: Richard A. Miller, M.D., Ph.D.

Administrative Core
Richard A. Miller, M.D., Ph.D., Director

Comparative Biogerontology Core
Richard A. Miller, M.D., Ph.D., Director

The core provides cells and tissues from a wide range of animal species that age at different rates, to encourage testing of hypotheses about the molecular and cellular controls of aging rate and longevity determination.

Research Development Core
Susan Brooks, Ph.D., Director

Functional Assessment Core
Gregory D. Cartee, Ph.D., Director

The core provides faculty with state-of-the-art facilities and technical assistance in the in vivo physiological assessments of the aging rodent.

Aging Rodent Core
Evan T. Keller, Ph.D., D.V.M., Director

The core supports daily maintenance and pathological analysis of rodents utilized for investigations of the cellular and molecular biology of aging and the relationship of the aging process to late life disease.

Drosophila Aging Core
Scott Pletcher, Ph.D., Director

The core provides access to equipment, genetic stocks, and expert training to researchers who wish to use fruit flies for studies of the control of aging in a short-lived, genetically malleable animal model.