Raymond Yung, MB.Ch.B

Title and department

Associate Professor of Internal Medicine, Division of Geriatric Medicine
Medical School
University of Michigan
Associate Director, Research
Veterans Affairs Ann Arbor
Healthcare System
Geriatric Research, Education,
and Clinical Center

Campus Address:

Rm. 3023 BSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109-2200

Phone: (734) 764-2266

Email address: ryung@umich.edu

Research Interests

Geriatric Rheumatology

Chemokine biology in aging

Gender and autoimmunity

Drug-induced autoimmunity

DNA methylation and gene regulation

Recent Publications

Yung RL, Powers D, Johnson K, Amento E, Carr D, Laing T, Yang J, Chang S, Hemati N, Richardson BC. Mechanisms of drug-induced lupus. II. T cells overexpressing LFA-1 cause a lupus-like disease in syngeneic mice J Clin Invest 1996;97:2866-2871.

Yung R, Williams R, Johnson K, Stoolman L, Chang S, Richardson B. Mechanisms of drug-induced lupus III. Gender specific differences in splenic T cell homing explain increased disease severity in female mice. Arthritis Rheum 1997;40:1334-1343.

Yung RL. Mechanisms of lupus: the role of estrogens. Clin Exp Rheumatol 1999;17:271-275.

Yung RL. Changes in Immune Function with Age. Rheum Dis Clin North Am 2000;26(3):455-473.

Yung R, Ray D, Eisenbraun JK, Deng C, Attwood J, Eisenbraun MD, Johnson K, Miller RA, Hanash S, Richardson B. Unexpected Effects of a Heterozygous Dnmt1 Null Mutation on Age-Dependent DNA Hypomethylation and Autoimmunity. J Gerontol Biol Sci 2001;56A(6):B268-276.

Mo RR, Chen J, Han Y, Bueno-Cannizares C, Misek DE, Pascal LE, Hanash S, Yung RL. T cell chemokine receptor expression in aging. J Immunol 2003;170:895-904.

Mo RR, Eisenbraun JK, Sonstein J, Craig RA, Curtis JL, Stoolman LM, Chen J, Yung RL. CD49d overexpression and T cell autoimmunity J Immunol 2003, 171:745-53.

Yung RL , Mo RR. Aging is Associated with Increase Human T Cell CC Chemokine Receptor Gene Expression J Interferon Cytokine Res 2003, 23:575-82.

Yung RL, Ray D, Mo RR, Chen J. T cell integrin overexpression as a model of murine autoimmunity. Biol Proced Online 2003, 5(1):211-21.

Chen J, Mo R, Lescure PA, Misek DE, Hanash S, Rochford R, Hobbs M, Yung RL. Aging is Associated with Increased T Cell Chemokine Expression in C57Bl/6 Mice. J Gerontol 2003; 58:975-983.

Brief Biography

Dr. Raymond Yung is an Associate Professor of Internal Medicine ( Medical School ) and a Research Scientist at the Veterans Affairs Ann Arbor Geriatric Research Education and Clinical Center. He obtained his medical school training from the University of Liverpool in England (1986). After completing an internal medicine residency at Sinai Hospital in Detroit, he received further clinical and research fellowship training in Rheumatology (1994) and Geriatric Medicine (1996) at the University of Michigan, where he has since remained a faculty member. Dr. Yung is a recipient of the NIH Individual National Research Service Award (1994-1996) and Clinical Investigator Award (1997-2002), and the American Federation for Aging Research Paul Beeson Physician Faculty Scholars in Aging Research Award (1998-2001). In addition, he has received the American College of Rheumatology Senior Rheumatology Scholar Award (1994). He is currently funded by the NIH in his research effort on the effects of aging on T cell chemokine function. In addition to his research endeavor Dr. Yung is also the Director of the Musculoskeletal Sequence in the Medical School curriculum.