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Ongoing Grants/Projects

Dominic Borgialli, DO, MPH

Pediatric Emergency Care Applied Research Network (PECARN)
The purpose of the EMSC-NDDP cooperative agreement is to continue to demonstrate the value of an infrastructure or network designed to be the platform from which to conduct investigations on the efficacy of treatments, transport, and care responses including those preceding the arrival of children to the hospital emergency departments.
Role: Co-Investigator/ Hospital Emergency Department Affiliate (HEDA) Director
Funding: Emergency Services for Children (EMSC) program/Maternal and Child Health Bureau (MCHB)/Health Resources and Services Administration (HRSA)
Sponsor: Great Lakes Emergency Medical Services for Children Research Node/
U03 MC 00003-08 (PI: RM Stanley)

Clinical Decision Rules to Detect Children with Blunt Traumatic Intra-abdominal Injuries
Role: Nodal Champion
Funding: Centers for Disease Control and Prevention
Sponsor: Great Lakes Emergency Medical Services for Children Research Node/Pediatric Emergency Care Applied Research Network (PECARN)
(PI: J. Holmes)

Rebecca M. Cunningham, MD

Substance Use Among Violently Injured Youth in an Urban ER: Services and Outcomes
Role: PI
National Institute on Drug Abuse
1R01DA024646-01A2

Characteristics of Patients Seeking Care at a Sub-saharian ER: GHANA
Role: Faculty Mentor (PI: Rocky Oteng)

Alcohol and Injury and Adolescents.  A Computer-based Intervention
University of Michigan Michigan Institute for Clinical and Health Research
Role:  Co-Investigator
MICHR Funding 48720 (Ehrlich)                                                                                                                                 
Adolescent Emergency Patients:  Suicide Risk Detection and Treatment Facilitation
Specific aims are: (1) to develop TOC materials (intervention manual; culturally tailored Services Information and Decision Aid; therapist training and fidelity assessment procedures); (2) to conduct a feasibility pilot study to refine the intervention and procedures for the randomized controlled trial; and (3) to conduct a pilot randomized controlled trial comparing TOC to enhanced treatment-as-usual.
Role:  Co-Investigator
National Institute of Mental Health       
PA-06-248 (King)      
                                                                                            
International Collaborative Alcohol & Injury Research Training Program in Poland
A multi-tiered research training program will be established through collaboration among researchers at UM and Wroclaw Medical University (WMU) and several other academic medical settings in Poland. This builds on a successful training and research collaboration between UM and Polish scientists at the Institute of Neurology and Psychiatry and the Medical Collage of Warsaw focused on substance use disorders. This new specific injury and alcohol collaboration brings together expertise in alcohol-related injury prevention, EMS/Trauma services, psychiatry, public health and transportation research at UM with a developing expertise in injury and trauma medicine and public health at WMU in order to increase training and research capacity in Poland. A consortium at WMU and academic medical and public health locations throughout Poland will be fostered through this collaborative effort. The program will train visiting Polish scientists at the UM in alcohol and injury research methodology, and develop mentored programs of research that address current issues in alcohol and injury prevention, treatment, and evaluation in Poland.
Role: Core Faculty Member.
PAR-04-083 (Blow F)
NIAAA /NIH

Tailored Teen Alcohol and Violence prevention in the ER
Develop and refine a tailored integrated prevention approach with different delivery mechanisms (Computer adapted motivational interviewing / skills training and Therapist adapted motivational interviewing / skills training interventions), that address both alcohol misuse and violence among adolescents ages 14-18 seeking care in an urban ED. Conduct a randomized controlled trial comparing the effectiveness of integrated tailored alcohol and violence prevention approaches with 3-, 6-, and 12-month outcomes. Examine the influence of key moderating variables (e.g., demographic and treatment process) and proximal outcome variables on intervention effectiveness.
Role: Co-PI
1 R01 AA014889-01A1 (Walton M)
NIAAA

Service Interventions for Injured ED Substance Abusers
The proposed five year study will screen patients presenting to an inner city Emergency Department for drug abuse/dependence. Those who meet criteria will be randomized into one of three drug abuse/dependence interventions: 1) a 5-session Strengths-Based Case Management (SBCM) model; 2) a 2-session Brief Motivational Enhancement (BME); or 3) a one-time Brief Informational Feedback (BIF) session. The interventions promote linkage to substance abuse assessment, referral, and treatment.
Role: Co-Investigator
1R01 DA016591 (Blow)
National Institute on Drug Abuse

Services Interventions for Injured ED Problem Drinkers
This proposed study will compare three alternative interventions in the ED to promote linkage and engagement in treatment for injured patients with alcohol abuse/dependence and has three specific conditions: 1) a 5-session Strengths-Based Case Management (SBCM) model; 2) a 2-session Motivational Enhancement Therapy (MET), or 3) a one-time Brief Informational Feedback (BIF) session. Patients who present to a large inner-city ED with injuries will be screened using a structured survey about alcohol use and consequences.
Role: Co-Investigator
1R01 AA014665-01A1 (Blow)
National Institute on Alcohol Abuse and Alcoholism

Peter F. Ehrlich, MD

A Clinical Decision Rule to Identify Children with Intra-abdominal Injuries.
Study in use of nominal CT’s in injured children, a clinical decision rule as to when to use them and when not to.
Role: Consultant
1 R49 CE001002 (PI: Holmes, J)
International Collaborative Alcohol and Injury Research Training Program in Poland
This program will train visiting Polish scientists at the UM in alcohol and injury research methodology, and develop mentored programs of research that address current issues in alcohol and injury prevention, treatment, and evaluation in Poland.
Role: Consultant
National Institutes of Health, Fogarty International Center
5D43TW007569 (PI: Blow)                                                                                                                

Development of a novel objective measure to monitor bicycle helmet use in children.
Pilot program to monitor and measure bicycle helmet use in children.
Role: PI
Office of the Vice Provost for Research University of Michigan

Alcohol and Injury and Adolescents.  A Computer-based Intervention
Role:  PI
University of Michigan - Michigan Institute for Clinical and Health Research
MICHR Funding 48720                                  

A brief tailored family- centered seatbelt intervention for hospitalized trauma patients
University of Michigan Transportation Research Institute (UMTRI) and NHTSA
Role: PI                       

Jolie Holschen, MD

Holschen J, Smith B. Survey on adequacy of teaching of sports medicine curriculum in emergency medicine residencies - survey of emergency medicine program directors and chief residents.

Correlation between the menstrual cycle and ligamentous ankle injury in women.
Role: PI
Department of Orthopedic Surgery, The University of Michigan

The Sports Medicine Core Curriculum Lecture Series (Teaching Grant)
Ten lectures on medical illness and musculoskeletal injuries afflicting athletic individuals, designed for web based self teaching by emergency physicians and residents.
American College of Emergency Physicians (Sports Medicine Section)
Role: Project Coordinator

Gender Differences in Neuropsychologic Parameters, Risk of Sustaining Concussion, and Recovery after Mild Traumatic Brain Injury
Role: PI
Wilpon Sports Injury Prevention Center Pilot Grants, The University of Michigan

Terry Kowalenko, MD

A Multi-site Intervention to Reduce Violence in Hospital Emergency Departments
Role: Principle Investigator

The Perception of Emergency Department Personnel of Violent Patient Encounters:  Development of a Data Collection Instrument
Role: Principle Investigator

MCEP Emergency Medicine Musculoskeletal Radiograph CD
Role: Content Editor

MCEP Emergency Medicine Ultrasound CD
Role: Co-Editor

ED Workplace Violence
Role: Principle Investigator

James M. Pribble, MD

Using the news media to disseminate booster seat information to the American public: How Police interact with the media and how can we improve it.
This proposed study will attempt to codify the process of police interaction with the local news media following motor vehicle crashes with specific attention being paid to the issue of booster seat usage. This will then lead to an understanding of the perceptions and beliefs of police officers regarding their potential role as media spokespeople for prevention following an MVC and to develop a web-based tool that may facilitate the interaction between police and the local news media.
Role: Principal Investigator
University of Michigan Transportation Research Institute

Alexander J. Rogers, MD

Pediatric Emergency Care Applied Research Network (PECARN)
Great Lakes Emergency Medical Services for Children Research Network
Role: Hospital Emergency Department Affiliate (PI: RM Stanley)

PECARN study of C-spine injuries in children
Role: site PI


Rachel Stanley, MD

Great Lakes Emergency Medical Services for Children Research Network
The purpose of the EMSC-NDDP cooperative agreement is to continue to demonstrate the value of an infrastructure or network designed to be the platform from which to conduct investigations on the efficacy of treatments, transport, and care responses including those preceding the arrival of children to the hospital emergency departments.
Role: PI
Health Resources and Service Administration
2 U03 MC 00003-08

BPCA Pediatric Off-Patent Drug Studies (PODS) Center – Lorazepam – Status Epilepticus
Role: Co-investigator and site PI
National Institute of Child Health and Human Development (NICHD) (Study 2)

Tailored Teen Alcohol and Violence prevention in the ER
Develop and refine a tailored integrated prevention approach with different delivery mechanisms (Computer adapted motivational interviewing / skills training (AMI+ST) and Therapist adapted motivational interviewing / skills training (AMI+ST) interventions), that address both alcohol misuse and violence among adolescents ages 14-18 seeking care in an urban ED.
Role: Co-investigator.
National Institute on Alcohol Abuse and Alcoholism
1 R01 AA014889-01A1 (PI: Walton, M)

Maureen Walton, MPH, PhD

Service Interventions for Injured ED Substance Abusers
The proposed five year study will screen patients presenting to an inner city Emergency Department for drug abuse/dependence. Those who meet criteria will be randomized into one of three drug abuse/dependence interventions: 1) a 5-session Strengths-Based Case Management (SBCM) model; 2) a 2-session Brief Motivational Enhancement (BME); or 3) a one-time Brief Informational Feedback (BIF) session. The interventions promote linkage to substance abuse assessment, referral, and treatment.
Role: Co-Investigator
1R01 DA016591 (Blow)
National Institute on Drug Abuse

Services Interventions for Injured ED Problem Drinkers
This proposed study will compare three alternative interventions in the ED to promote linkage and engagement in treatment for injured patients with alcohol abuse/dependence and has three specific conditions: 1) a 5-session Strengths-Based Case Management (SBCM) model; 2) a 2-session Motivational Enhancement Therapy (MET), or 3) a one-time Brief Informational Feedback (BIF) session. Patients who present to a large inner-city ED with injuries will be screened using a structured survey about alcohol use and consequences.
Role: Co-Investigator
1R01 AA014665-01A1 (Blow)
National Institute on Alcohol Abuse and Alcoholism

Age-Related Services and Outcomes After DUI Interventions
Role: Co-Investigator
National Institute on Alcohol Abuse and Alcoholism (PI: Blow)

Tailored Teen Alcohol and Violence prevention in the ER
Develop and refine a tailored integrated prevention approach with different delivery mechanisms (Computer adapted motivational interviewing / skills training and Therapist adapted motivational interviewing / skills training interventions), that address both alcohol misuse and violence among adolescents ages 14-18 seeking care in an urban ED. Conduct a randomized controlled trial comparing the effectiveness of integrated tailored alcohol and violence prevention approaches with 3-, 6-, and 12-month outcomes. Examine the influence of key moderating variables (e.g., demographic and treatment process) and proximal outcome variables on intervention effectiveness.
Role: PI
1 R01 AA014889-01A1
NIAAA

Tailored Youth Drug Intervention in Primary Care
Role: Co-Investigator
National Institute on Drug Abuse (PI: Blow)

Tailored Web Progam to Reduce At-Risk College Drinking
Role: Co- Investigator
National Institute on Alcohol Abuse and Alcoholism (P: Bingham)

Forgarty International Collaborative Alcohol and Injury Research Training Program in Poland
This program will train visiting Polish scientists at the UM in alcohol and injury research methodology, and develop mentored programs of research that address current issues in alcohol and injury prevention, treatment, and evaluation in Poland.
Role: Core Faculty
National Institutes of Health, Fogarty International Center
5D43TW007569 [Blow (PI)]

Adolescent Emergency Patients: Suicide Risk Detection and Treatment Facilitation
Role: Co-Investigator
National Institute on Mental Health (PI: King)

Alcohol and Injury and Adolescents.  A Computer-based Intervention
University of Michigan Michigan Institute for Clinical and Health Research
Role:  Consultant
MICHR Funding 48720 (PI: Ehrlich)

Recently Completed Grants/Projects

Dominic Borgialli, DO, MPH

Great Lakes Emergency Medical Services for Children Research Node
Pediatric Emergency Care Applied Research Network (PECARN)
The purpose of the EMSC-NDDP cooperative agreement is to continue to demonstrate the value of an infrastructure or network designed to be the platform from which to conduct investigations on the efficacy of treatments, transport, and care responses including those preceding the arrival of children to the hospital emergency departments.
Role: Hospital Emergency Department Affiliate (HEDA) Director/ Co-investigator
DHHS/MCHB/EMSC
2 U03 MC 00003-05 (PI: RF Maio)

Rebecca M. Cunningham, MD

Integrated Care for Medicaid Consumers with Behavioral Health Care Needs
The overall goal of this project is to demonstrate a system for integrating the care of citizens with severe and persistent mental illness, developmental disability and/or a substance abuse disorder.
State of Michigan, Department of Community Health                            
Role:  Co-Investigator
20052588 (King/Neal, PI)                                                                                                                                           
Injury Prevention Efforts at US Trauma Centers; ED Director Survey in Level I and Level II Trauma Centers
This study will survey ED directors at Level I and II trauma centers to assess the types of alcohol interventions currently in use and the extent of knowledge of SBI for alcohol.
Role: PI
ACEP Section Grant (Section of Trauma and Injury Prevention)
                                                                                         
Cocaine & Chest Pain in the ED: Services and Outcomes
 The specific aims of the study are: 1) To develop a comprehensive portrait of a consecutive cohort of cocaine users presenting to the ED with chest pain. 2. To identify specific locations where study participants interact with the health service system in the year following their ED visit and to identify the key patient characteristics associated with types of service use.  3. To identify access barriers to engaging in treatment and use of other services including primary care. 4. To measure one-year outcomes for this cohort and to identify key socio-demographic and clinical characteristics of cocaine-using individuals associated with outcomes in the year after their ED visit for chest pain.
Role:  Co-Investigator
National Institute on Drug Abuse (NIDA) (NIH)
R-01-DA14343-01 (Booth)
                                                                                                 
Flint Youth Violence Prevention Center
Pilot Project: Brief Emergency Department Intervention (Maio, R. PI)
The specific aims of the Center are to: 1) build the scientific infrastructure to support the development of community-wide youth violence prevention interventions; 2) promote interdisciplinary strategies that foster collaboration; 3) work with community members to address youth violence prevention; 4) institutionalize violence prevention in health provider practice and training; and 5) develop an evaluation plan and surveillance system to monitor progress. The pilot project will adapt an existing alcohol related intervention in the Emergency Department for youth violence prevention. The web-based intervention will be designed to include an interactive component addressing violence prevention. The web-site program content will be based on risk and resiliency factors associated with violence and will include connections between alcohol use and violence, as well as violence not associated with alcohol use.
Role: Co-Investigator
R-49-CCR-518605-01 (Zimmerman)
Centers for Disease Control, Injury Control Center

Emergency Medicine National Alcohol Screening Day Alcohol Education Project
The purpose of this research study is to determine the effectiveness of Emergency Department Physicians in giving brief counseling on alcohol misuse to patients seen in the Emergency Department. Approximately 1000 patients from all 14 sites will be involved in the study. At three and six months following their ED visits, patients in both the treatment and control conditions will complete follow-up interviews by telephone using Interactive Voice Response (IVR) technology. Study aims include: the promotion of the adoption of screening, brief intervention and referral to treatment for alcohol abuse (SBIRT) among emergency department (ED) providers in accordance with the Healthy People 2010 objective 26-22, and thus improve the health of ED patients with alcohol use disorders.
Role: Co-Investigator
1 R03 AA015111-01 (Bernstein)
National Institute on Alcohol Abuse and Alcoholism (NIH)
National Alcohol Screening Day Emergency Department Study

Peter F. Ehrlich, MD

Novel Approaches to Pediatric Injury Prevention
Objective - a. Refine and test the feasibility of a novel secondary injury prevention tool that increases seatbelt use by parents and children as well as to increase the number of children less than 12 years of age properly positioned in the back seat when riding in a car.
b. Use the data as building blocks to obtain peer reviewed funding for a randomized control trial (RCT) of this injury prevention tool.
Role: Principal Investigator
American Pediatric Surgery Foundation Scholarship


Terry Kowalenko, MD

ED Violence
Role: Co-Principal Investigator
American College of Emergency Medicine
Physicians Michigan Chapter Grant

The Efficacy Trial of Diaspirin Cross-Linked Hemoglobin (DCLHbTM) in the Treatment of Severe Hemorrhagic Shock
Role: Site Principal Investigator
Baxter HealthCare Corporation

James M. Pribble, MD

Analysis of how unintentional injury is reported on local TV
This project studies how the television news media reports injury and how this information can impact public perceptions and the policy agenda regarding injury prevention.
Role: Principal Investigator
Center for Disease Control and Prevention
Injury Research Center at Medical College of Wisconsin

Local Television Health News: What are they talking about?
Largest study to date of broadcast news reporting of health information. Specifically, content analysis of top 50 local television news markets in the United States to determine what health topics were reported and the nature of the reporting.
Role: Principal Investigator (As research Fellow)
Robert Wood Johnson Clinical Scholars Program / VA

 

Alexander J. Rogers, MD

Analgesic Effect of Oral Sucrose
Children’s Research Oversight Committee
Role: Co-PI


Rachel Stanley, MD

Great Lakes Emergency Medical Services for Children Research Network
The purpose of the EMSC-NDDP cooperative agreement is to continue to demonstrate the value of an infrastructure or network designed to be the platform from which to conduct investigations on the efficacy of treatments, transport, and care responses including those preceding the arrival of children to the hospital emergency departments.
Role: PI
Health Resources and Service Administration
2 U03 MC 00003-05

PECARN. Pediatric Applied Research Network. 
The purpose of the EMSC-NDDP cooperative agreement is to continue to demonstrate the value of an infrastructure or network designed to be the platform from which to conduct investigations on the efficacy of treatments, transport, and care responses including those preceding the arrival of children to the hospital emergency departments. 
Role: Site PI, 10%
Maternal and Child Health Bureau (MCHB)
4D1BTH00026-01-03 (PI: Maio, R)                                                             

Childhood Head Trauma: A Neuroimaging Decision Rule
Goal: to derive a decision rule for identifying children at low and high risk of traumatic brain injury after head trauma.
Role:  Co-investigator.
Maternal and Child Health Bureau (MCHB)
R40MC02461-01-00 (PI: Kuppermann)                                                                          

Pharmacokinetic study of Lorazepam in pediatric epileptics.
This is a pharmacokinetic study of lorazepam in children with epilepsy.
Role: Site PI
NICHD-2003-10 and FDA (PI: Chamberlain)
FDA (Study 1)

Maureen Walton, MD

The use of tailored brief intervention messages in the emergency department
Role: Co-Investgator
National Institute on Alcoholism and Alcohol Abuse (PI: Blow)

Flint Youth Violence Prevention Center
Pilot Project: Brief Emergency Department Intervention (Maio, R. PI)
The specific aims of the Center are to: 1) build the scientific infrastructure to support the development of community-wide youth violence prevention interventions; 2) promote interdisciplinary strategies that foster collaboration; 3) work with community members to address youth violence prevention; 4) institutionalize violence prevention in health provider practice and training; and 5) develop an evaluation plan and surveillance system to monitor progress. The pilot project will adapt an existing alcohol related intervention in the Emergency Department for youth violence prevention. The web-based intervention will be designed to include an interactive component addressing violence prevention. The web-site program content will be based on risk and resiliency factors associated with violence and will include connections between alcohol use and violence, as well as violence not associated with alcohol use.
Role: Co-Investigator
R-49-CCR-518605-01 (Zimmerman)
Centers for Disease Control, Injury Control Center

Cocaine & Chest Pain in the ED: Services and Outcomes
 The specific aims of the study are: 1) To develop a comprehensive portrait of a consecutive cohort of cocaine users presenting to the ED with chest pain. 2. To identify specific locations where study participants interact with the health service system in the year following their ED visit and to identify the key patient characteristics associated with types of service use.  3. To identify access barriers to engaging in treatment and use of other services including primary care. 4. To measure one-year outcomes for this cohort and to identify key socio-demographic and clinical characteristics of cocaine-using individuals associated with outcomes in the year after their ED visit for chest pain.
Role:  Co-Investigator
National Institute on Drug Abuse (NIDA) (NIH)
R-01-DA14343-01 (PI: Booth)

Developing Violence Therapy for Substance Abusers
Role: Co- Investigator
National Institute on Drug Abuse (PI: Chermack)


 

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