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Hematology Sequence Laboratories 2015


1. Hematopathology Lab Introduction (this document)
2. Hematopathology Atlas 2015.pptx
3. Hematopathology Lab 1 2015 Anemias and Leukocytoses.ppt
4. Hematopathology Lab 2 2015 Neoplasms.pptx


The laboratories focus on the microscopic, genetic and immunologic features of blood cells essential for the diagnosis of hematologic disorders.

  1. The first week is a Self-Study exercise using the Hematopathology Atlas 2015 PowerPoint document. This exercise (1) reviews the organization of hematopoietic organs,
    (2) introduces the terminology used to describe blood cells and (3) demonstrates the microscopic features of normal and abnormal blood smears.
  2. The second week consists of two in-class laboratories that use the Hematopathology Labs 1 & 2 PowerPoint documents. These illustrate the laboratory diagnosis of anemias, luekocytoses and hematologic neoplasms.
  3. All materials covered on the examination are contained in the three PowerPoint documents including (1) photomicrographs, (2) link to virtual slides, (3) review material and (4) cases with questions/answers (see below).
  4. We strongly encourage you to attend the in-class laboratories. These are interactive sessions, not mini-lectures, are staffed by Hematopathology faculty selected for teaching excellence. Great opportunity to get questions about laboratory diagnosis and lecture material answered. Video recordings will not be made since (1) they cannot capture the image detail needed to learn cell identification and (2) all relevant factual information is in the PowerPoint documents. If you do not attend the labs, then work through the PowerPoint documents on your own, study the photomicrographs and virtual slide, learn the factual content and test your identification skills using the self-test tools provided.
  5. Links to diagnostic quality virtual slides are provided in the PowerPoint documents and used during the in-class labs. Please bring your laptops.
  6. The final exam includes 5 questions based on the photomicrographs in the Atlas and 5 questions based on the 9 virtual slides covered in the in-class laboratories.
  7. The Self-study Atlas has a test preparation mode and a Web-based “self-test” tools provided for the virtual slides (Virtual Slides Self-Tester, link from Laboratory PowerPoints described below)

Objectives for self-study using the Hematopathology Atlas 2015 (1-05 thru 1-12)

The Atlas 2015 PowerPoint document should be viewed initially using the “normal” view mode so that the slides and the “notes” window below are visible (content in both windows). For test preparation, view Atlas as a PowerPoint so that “notes” section is not visible.

  1. Learn the microscopic appearance and frequency distribution of normal erythrocytes, leukocytes, selected anemias and selected neoplastic cells.
  2. Know where normal blood cell growth, differentiation and maturation occur.
  3. Know the meanings of the terms stem cell, progenitor, precursor, mature and effector cells.
  4. Understand how a blood smear is prepared and evaluated.
  5. Know the regions of a blood smear and how to find the optimal areas for microscopic evaluation.
  6. Know the stage(s) of red and white blood cell maturation that are normally present in the blood.
  7. Know the common terms used to describe RBC shapes and sizes.
  8. Identify platelets, mature and immature erythrocytes, selected erythrocyte abnormalities in Atlas.
  9. Identify normal mature, activated and immature white blood cells in the blood smear.
  10. Identify selected abnormal and neoplastic leukocytes in Atlas.

Instructions for in-class Hematopathology Lab 1 (1/13) and Lab 2 (1/15)

  1. Hematopathology Lab 1 2015 Anemias and Leukocytoses and Hematopathology Lab 2
    2015 Neoplasms documents
  2. These documents are best viewed from (1) desktops on campus network or (2) a laptop
    attached to the Medical School’s intranet
    (Ethernet connection best, Wi-Fi OK).
    3. Tablets are NOT recommended since special software is required for virtual slide viewing
    and the links to virtual slides in the PowerPoint document will not work.

Using the PowerPoint documents:

  1. Place the PowerPoint document on your desktop and open. Initiate the “Slideshow” mode
    using the “screen” icon or the appropriate dropdown menu. Resize the slideshow window
    for comfortable viewing and proceed.
  2. Use the space-bar, arrow keys or mouse to move forward (or backward) through the case
    history, illustrative micrographs (from virtual slides), questions and answers for each case.
  3. Make sure to study the virtual slides using the links provided in the PowerPoint.
  4. A link is also provided to a Web-based self-test tool for virtual slides review.
  5. In the classroom laboratory, the instructor will introduce each case then ask students to
    work through the questions, answers and virtual slides using the PPS on their laptops.
    He/she will answer individual questions as they arise and address areas of common
  6. Remember, five of the virtual slides used in the laboratory will appear on the final exam so look at these along with the photomicrographs in the Laboratory exercise


Technical Problems or questions? email| ph. 734-936-2239

Content Questions? Dr. Killen:

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