Research

The faculty, staff, and residents of the U-M Dermatology Department use state-of-the-art approaches to further the understanding of normal skin biology and a wide range of skin disorders. Advances that elucidate disease mechanisms may lead to the development of novel and more effective approaches to treatment. Under the direction of John J. Voorhees, MD, FRCP, our department has grown to include diverse, world-class research programs in basic science and clinical studies, with a focus on dynamic, multidisciplinary interactions.

Cancer Biology - Andrzej Dlugosz, M.D., Director

• Andrzej Dlugosz, M.D.: Embryonic signaling pathways in development, regeneration, and cancer

Psoriasis Genetics & Pathophysiology - J.T. Elder, M.D. Ph.D., Director

• J.T. Elder, M.D. Ph.D. and Johann Gudjonsson, M.D. Ph.D.: Genetics and immunopathology of psoriasis; autocrine regulation of keratinocyte growth
• Rajan Nair, Ph.D., and J.T. Elder, M.D. Ph.D.: Genetics of psoriasis and psoriatic arthritis
• Stefan Stoll, Ph.D.: ErbB regulation of epidermal growth and differentiation

Photoaging & Aging Skin - Gary Fisher, Ph.D., Director

• Gary Fisher, Ph.D.: Cutaneous photobiology and aging
• Tai Hao Quan, Ph.D.: Molecular mechanisms of human skin natural aging and photoaging
• Yiru Xu, Ph.D.: Mechanism of ultraviolet light-induced signaling transduction in skin photoaging and cancer

Clinical Research - John Voorhees, M.D., Director

• Yolanda Helfrich, M.D. and Dana Sachs, M.D.: Clinical pharmacology unit drug trials and clinical trials; acne and rosacea research; photoaging and aging skin research
• Timothy Johnson, M.D.: Melanoma and non-melanoma tissue banks
• Darius Karimipour, M.D.: Molecular mechanisms of skin remodeling following cosmetic microdermabrasion
• Jeffrey Orringer, M.D.: Clinical and biochemical results of laser therapy and other cosmetic dermatology therapies