TaiHao Quan, M.D., Ph.D.

Research Associate Professor, Department of Dermatology

Selected Publications

1. Quan TH, Fisher GJ: Cloning and Characterization of the Human Protein Kinase C h Promoter. J Biol Chem, 274:28566-28574, 1999.
2. Fisher GJ, Datta S, Wang Z, Li XY, Quan T, Chung JH, Kang S, Voorhees JJ: c-Jun-Dependent Inhibition of Cutaneous Procollagen Transcription Following Ultraviolet Irradiation is Reversed by All-trans Retinoic Acid. J Clin Invest, 106(5):663-670, 2000.
3. Quan T, He TY, Voorhees JJ, Fisher GJ: Ultraviolet Irradiation Blocks Cellular Responses to Transforming Growth Factor-b by Down-Regulation of its Type-II Receptor and Inducing Smad7. J Biol Chem, 276:26349-26356, 2001.
4. Quan T, He T, Kang S, Voorhees JJ, Fisher GJ: Connective Tissue Growth Factor (CTGF): Expression in Human Skin in vivo and Inhibition by Ultraviolet Irradiation. J Invest Dermatol, 118:402-408, 2002.
5. Quan T, He TY, Kang S, Voorhees JJ, Fisher GJ: Ultraviolet Irradiation Alters Transforming Growth Factor-h/Smad Pathway in Human Skin in vivo. J Invest Dermatol, 119:499-506, 2002.
6. Wang HQ, Quan T, He TY, Franke TF, Voorhees JJ, Fisher GJ: Epidermal Growth Factor Receptor-dependent, NF-κB-independent Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Inhibits Ultraviolet Irradiation-induced Caspases-3,-8, and -9 in Human Keratinocytes. J. Biol Chem, 278, 45737-45745, 2003.
7. Quan T, He TY, Kang S, Voorhees JJ, Fisher GJ: Solar UV Irradiation Reduces Collagen in Photoaged Human Skin by Blocking TGF-β Type II Receptor/SMAD Signaling, Amer J Pathol, 165:741-751, 2004.
8. Quan T, He TY, Kang S, Voorhees JJ, Fisher GJ: Solar UV Irradiation Reduces Collagen in Photoaged Human Skin by Blocking TGF-β Type II Receptor/SMAD Signaling, Amer J Pathol, 165:741-751, 2004.
9. Quan T, He T, Voorhees JJ, and Fisher GJ: Ultraviolet Irradiation Induces SMAD7 via Induction of Transcription Factor AP-1 in Human Skin Fibroblasts. J. Biol. Chem., 280,8079-8085, 2005.