Johann E. Gudjonsson, M.D., Ph.D.

Lecturer, Department of Dermatology

Selected Publications

1. Clin. Exp. Immunolog. 2001: 126:365-369. The Frequency of CLA+ CD8+ T Cells in the Blood of Psoriasis Patients Correlate Closely with the Severity of Their Disease. H. Sigmundsdottir, JE Gudjonsson, I Jonsdottir, BR Ludviksson, H Valdimarsson.
2. J. Invest. Dermatol 2002 Feb;118:362-365. HLA-Cw6-Positive and HLA-Cw6-Negative Patients With Psoriasis Vulgaris Have Distinct Clinical Features. JE Gudjonsson, A Karason, AA Antonsdottir, EH Runarsdottir, JR Gulcher, K Stefansson, H Valdimarsson.
3. American Journal of Human Genetics 2003 Jan; 72: 125-132. A Susceptibility Gene For Psoriatic Arthritis Maps To Chromosome 16q: Evidence For Imprinting. A Karason, JE Gudjonsson, R Upmanyu, AA Antonsdottir, VB Hauksson, EH Runarsdottir, H Jonsson , K Stefansson, H Valdimarsson, J Gulcher.
4. British Journal of Dermatology. 2003 Feb;148:233-5. Psoriasis Patients Who Are Homozygous for the HLA-Cw602 Allele have a Three-Fold Increased Risk of Getting Psoriasis than Cw6 Heterozygotes. JE Gudjonsson, A Karason, AA Antonsdottir, EH Runarsdottir, JR Gulcher, K Stefansson, H Valdimarsson.
5. Clin. Exp Immunolog. 2003. Interleukin-12 Alone Can Not Enhance The Expression of the Cutaneous Lymphocyte Associated Antigen (CLA) By Superantigen Stimulated T Lymphocytes. H Sigmundsdottir, JE Gudjonsson, H Valdimarsson.
6. British Journal of Dermatology 2003. The Effects of UVB Treatment on the Expression of Adhesion Molecules by Circulating T Lymphocytes in Psoriasis. H Sigmundsdottir, JE Gudjonsson, H Valdimarsson.
7. The British Journal of Dermatology 2003 Sept; 149:530-4. Streptococcal Throat Infections and Exacerbation of Chronic Plaque Psoriasis - A Prospective Study. JE Gudjonsson, AM Thorarinsson, KG Kristinsson, H Valdimarsson.
8. Scand J Immunol 2004 Jan; 59:97-102. Human Plasma-Derived Mannose-Binding Lectin: A Phase I Safety and Pharmacokinetic Study. H Valdimarsson, T Vikingsdottir, P Bang, S Saevarsdottir, JE Gudjonsson, O Oskarsson, M Christiansen, L Blou, I Laursen, C Koch.
9. Clin. Exp Immunol 2004 Jan; 135:1-8: Immunopathogenic Mechanisms in Psoriasis. JE Gudjonsson, A Johnston, H Sigmundsdottir, H Valdimarsson.
10. Clin Immunol 2004 Apr; 111:119-25. Differential Effects of Interleukin 12 and Interleukin 10 on Superantigen-Induced Expression of Cutaneous Lymphocyte-Associated Antigen (CLA) and Alphaebeta7 Integrin (CD103) By CD8+ T Cells. H Sigmundsdottir, A Johnston, JE Gudjonsson, H Valdimarsson.
11. Exp Dermatol 2004 Jul; 13:426-34. Methotrexate Markedly Reduces the Expression of Vascular E-Selectin, Cutaneous Lymphocyte Associated Antigen and The Numbers of Mononuclear Leucocytes in Psoriatic Skin. H Sigmundsdottir, A Johnston, JE Gudjonsson, B Bjarnason, H Valdimarsson.
12. Curr Rheumatol Rep 2004 Aug; 6:314-6. Psoriasis: A Complex Clinical and Genetic Disorder. H Valdimarsson, A Karason, JE Gudjonsson.
13. Clin. Exp Immunol 2004 Oct;138:83-93: Peripheral Blood T Cell Responses to Keratin Peptides that Share Sequences with M Proteins are Largely Restricted to Skin-Homing CD8+ T Cells. A Johnston, JE Gudjonsson, H Sigmundsdottir, T Love, H Valdimarsson
14. Clin Immunol 2005 Feb;114:154-63. The Anti-Inflammatory Action of Methotrexate is not Mediated by Lymphocyte Apoptosis, but by the Suppression of Activation and Adhesion Molecules. A Johnston, JE Gudjonsson, BR Ludviksson, H Valdimarsson.
15. J Invest Dermatol 2005 May;124:921-30: Fine Mapping of the Psoriasis Susceptibility Gene PSORS1: A Reassessment of Risk Associated With a Putative Risk Haplotype Lacking HLA-Cw6. The Cluster 17 Collaboration.
16. J Invest Dermatol 2005 June; 124:1177-85: Genetics of Psoriasis in Iceland: Evidence for Linkage of Subphenotypes to Distinct Loci. A Karason, JE Gudjonsson, HH Jonsson, VB Hauksson, EH Runarsdottir, K Stefansson, H Valdimarsson, JR Gulcher.
17. Arch Dermatol Res 2005 July;297:39-42: Narrow-Band UVB Irradiation Induces The Secretion of Anti-Inflammatory Cytokines and Suppresses The Secretion of Pro-Inflammatory Cytokines by Activated Pbmcs from Psoriasis Patients. H Sigmundsdottir, A Johnston, JE Gudjonsson, H Valdimarsson.
18. Eur J Hum Genet 2006 Jan;14(1):2-4: Mouse Models: Psoriasis: An Epidermal Disease After All? Gudjonsson JE, Elder JT.
19. J Invest Dermatol 2006 April;126(4):740-5: Distinct Clinical Differences Between HLA-Cw*0602 Positive and Negative Psoriasis Patients - An Analysis of 1019 HLA-C and B Typed Patients. JE Gudjonsson, A Karason, A Antonsdottir, EH Runarsdottir, VB Hauksson, HH Jonsson, J Gulcher, K Stefansson, H Valdimarsson.
20. J Invest Dermatol 2007 Jun;127(6):1292-308: Mouse Models of Psoriasis Gudjonsson JE, Johnston A, Dyson M, Valdimarsson H, Elder JT.
21. Am J Pathol 2007 Jun;170(6):2089-99: Evidence for Differential Autocrine ErbB Signaling in Squamous Cell vs. Basal Cell Carcinoma of the Skin (in press). Rittie L, Kansra S, Stoll SW, Li Y, Gudjonsson JE, Zhang T, Shao Y, Fisher GJ, Boyd C, Johnson T, Elder JT.
22. Clinics in Dermatology (in press): Epidemiology of Psoriasis Gudjonsson JE, Elder JT.
23. Journal of Rheumatology 2007 Oct;34(10):2082-8: Psoriatic Arthritis in Reykjavik, Iceland: Prevalence, Demographics and Disease Course Love TJ, Gudbjornsson B, Gudjonsson JE, Valdimarsson H
24. Archives of Dermatology (in press): Multi-nodular lesions of the earlobes. Do TT, Gielczyk R, Wang T, Olsen S, Lowe L, Gudjonsson JE.