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Andrew Johnston, PhD

Assistant Research Professor, Department of Dermatology

Selected Publications

  1. Sigmundsdottir H, Johnston A, Gudjonsson JE, Valdimarsson H. Differential effects of interleukin-12 and interleukin-10 on the superantigen-induced expression of cutaneous lymphocyte-associated antigen (CLA) and alphaE beta7 (CD103) integrin by CD8+ T cells. Clinical Immunology. 2004;111:119-125.
  2. Sigmundsdottir H, Johnston A, Gudjonsson JE, Bjarnason B, Valdimarsson H. Methotrexate markedly reduces the expression of vascular E-selectin, cutaneous lymphocyte-associated antigen (CLA) and the numbers of mononuclear leukocytes in psoriatic skin. Experimental Dermatology. 2004;13:426-434.
  3. Johnston A, Gudjonsson JE, Sigmundsdottir H, Love TJ, Valdimarsson H. Peripheral blood T cell responses to keratin peptides that share sequences with streptococcal M proteins are largely restricted to skin homing CD8+ T cells. Clinical and Experimental Immunology. 2004;138:83-93.
  4. Johnston A, Gudjonsson JE, Sigmundsdottir H, Ludviksson BR, Valdimarsson H. The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules. Clinical Immunology. 2005;114:154-163.
  5. Sigmundsdottir H, Johnston A, Gudjonsson JE, Valdimarsson H. Narrowband-UVB irradiation decreases the production of pro-inflammatory cytokines by stimulated T cells. Archives of Dermatological Research. 2005;297(1):39-42.
  6. Johnston A, Arnadottir S, Gudjonsson JE, Aphale A, Sigmarsdottir AA, Gunnarsson SI, Steinsson JT, Elder JT, Valdimarsson H. Obesity in psoriasis: Leptin and resistin as mediators of cutaneous inflammation. British Journal of Dermatology. 2008;159(2):342-350.
  7. Kryczek I, Bruce AT, Gudjonsson JE, Johnston A, Aphale A, Vatan L, Szeliga W, Wang Y, Liu Y, Welling TH, Elder JT, Zou W. Induction of IL-17+ T cell trafficking and development by IFN-gamma: Mechanism and pathological relevance in psoriasis. Journal of Immunology. 2008;181:4733-4741.
  8. Li Y, Gudjonsson JE, Woods TL, Zhang T, Johnston A, Stoll SW, Elder JT. Transgenic expression of S100A2 in hairless mouse skin enhances Cxcl13 mRNA in response to solar-stimulated radiation. Arch Dermatol Res. 2009;301(3):205-217.
  9. Valdimarsson H, Thorleifsdottir RH, Sigurdardottir SL, Gudjonnson JE, Johnston A. Psoriasis - as an autoimmune disease caused by molecular mimicry. Trends Immunol. 2009;30(10):494-501.
  10. Johnston A, Sigurdardottir SL, Ryon JJ. Isolation of mononuclear cells from tonsillar tissue. In: Current Protocols in Immunology. 2009:Chapter 7:Unit 7.8.
  11. Stoll SW, Johnson JL, Bhasin A, Johnston A, Gudjonsson JE, Rittie L, Elder JT. Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skin. J Invest Dermatol. 2010;130(1):295-304.
  12. Gudjonsson JE, Johnston A, Stoll SW, Riblett M, Ding J, Nair RP, Aphale A, Voorhees JJ, Elder JT. Evidence for altered Wnt signaling in psoriatic skin. J Invest Dermatol. 2010. (in press)


 

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