Speeding the Search for
Bipolar Genes
 For the 5.7 million Americans with bipolar disorder, the manic “highs” and the deep depressed “lows” they experience are bad enough. But they also live with the knowledge that their loved ones, especially their children, are at risk of developing the disease. Although no single gene causes bipolar disorder, the disease has its roots in genetic vulnerabilities that run in families.
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Research
The Depression Center research programs build on a long tradition
of excellence. Ongoing research conducted within the Depression
Center allows investiagtors to continually improve treatment
options. Clinicians work side-by-side with biological researchers
who move treatment advances from "bench to bedside"
allowing our patients to take immediate advantage of them.
Researchers study and evolve new models for treatment, prevention
and for minimizing recurrences. Internationally recognized
faculty in biologic treatments, neuroimaging, genetics, immunology
and stress anchor the Center's research.
There are a number of different types of research involving
people with depression. Clinical
trials are one important type of patient related research.
In addition, research may include studies designed to understand
underlying biological and psychological changes that may make
some individuals more likely to experience to depression,
or studies designed to document the effects of the illness,
and studies designed to prevent long-term consequences of
the illness e.g. suicide or prevention. The Depression Center
conducts ongoing studies focusing on all of these areas.
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Psychiatric Neuromodulation Program |
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Prechter Bipolar Genes Project |
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Sleep and Chronophysiology Lab |
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STAR*D |
Great expectations: U-M study looks at placebo effect
 Why do some people experience a “placebo effect” that makes them feel better when they receive a sham treatment they believe to be real — while other people don’t respond at all to the same thing, or even feel worse?
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NIH interpretation of "Translational" research
NIH research funding is more difficult to obtain during recent years, especially for "basic" types of submissions. One major reason is NIH's prioritization of "translational" research. This term is sometimes puzzling. What is meant by basic versus translational research?
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