Manuscripts Published or In Press
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Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, Evangelista A, Fattori R, Suzuki T, Oh JK, Moore AG, Malouf JF, Pape LA, Gaca C, Sechtem U, Lenferink S, Deutsch HJ, Diedrichs H, Robles JM, Llovet A, Gilon D, Das SK, Armstrong WF, Deeb GM, Eagle KA. The International Registry of Aortic Dissection (IRAD): New insights into an old disease. JAMA 2000; 283(7):897-903.
Mehta RH, Suzuki T, Hagan PG, Bossone E, Gilon D, Llovet A, Maroto LC, Cooper JV, Smith DE, Armstrong WF, Nienaber CA, Eagle KA. Predicting death in patients with acute type A aortic dissection. Circulation 2002; 105(2):200-206.
Januzzi JL, Sabatine MS, Eagle KA, Evangelista A, Bruckman D, Fattori R, Oh JK, Moore AG, Sechtem U, Llovet A, Gilon D, Pape L, O’Gara PT, Mehta R, Cooper JV, Hagan PG, Armstrong WF, Deeb GM, Suzuki T, Nienaber CA, Isselbacher EM. Iatrogenic aortic dissection. Am J of Cardiology 2002; 89(5):623-626.
Moore AG, Eagle KA, Bruckman D, Moon BS, Malouf JF, Fattori R, Evangelista A, Isselbacher EM, Suzuki T, Nienaber CA, Gilon D, Oh JK. Choice of computed tomography, transesophageal echocardiography, magnetic resonance imaging, and aortography in acute aortic dissection: International Registry of Acute Aortic Dissection (IRAD). Am J of Cardiology 2002; 89:1235-1238.
Bossone E, Rampoldi V, Nienaber CA, Trimarchi S, Ballotta A, Cooper JV, Smith DE, Eagle KA, Mehta RH. Usefulness of pulse deficit to predict in-hospital complications and mortality in patients with acute type A aortic dissection. Am J of Cardiology 2002; 89:851-855.
Nallamothu BK, Mehta RH, Saint S, Llovet A, Bossone E, Cooper JV, Sechtem U, Isselbacher EM, Nienaber CA, Eagle KA, Evangelista A. Syncope in acute aortic dissection: diagnostic, prognostic, and clinical implications. Am J of Medicine 2002; 113:468-471.
Mehta RH, O’Gara PT, Bossone E, Nienaber CA, Myrmel T, Cooper JV, Smith DE, Armstrong WF, Isselbacher EM, Pape LA, Eagle KA, Gilon D. Acute type A aortic dissection in the elderly: clinical characteristics, management and outcomes in the current era. J Am Coll Cardiol 2002; 40:685-692.
Mehta RH, Manfredini R, Hassan F, Sechtem U, Bossone E, Oh JK, Cooper JV, Smith DE, Portaluppi F, Penn M, Hutchison S, Nienaber CA, Isselbacher EM, Eagle KA. Chronobiological patterns of acute aortic dissection. Circulation 2002; 106:1110-1115.
Eagle KA, Isselbacher EM, DeSanctis RW. Cocaine-related aortic dissection in perspective. Circulation 2002; 105:1529-1530.
Nienaber CA, Eagle KA. Aortic dissection: new frontiers in diagnosis and management. Part I: from etiology to diagnostic strategies. Circulation 2003; 108:628-635.
Nienaber CA, Eagle KA. Aortic dissection: new frontiers in diagnosis and management. Part II: therapeutic management and follow-up. Circulation 2003; 108:772-778.
Suzuki T, Mehta RH, Ince H, Nagai R, Sakomura Y, Weber F, Sumiyoshi T, Bossone E, Trimarchi S, Cooper JV, Smith DE, Isselbacher EM, Eagle KA, Nienaber CA. Clinical profiles and outcomes of acute type B aortic dissection– lessons from the International Registry of Aortic Dissection (IRAD). Circulation 2003; 108[suppl II]:312-317.
Januzzi JL, Isselbacher EM, Fattori R, Cooper JV, Smith DE, Fang J, Eagle KA, Mehta RH, Nienaber CA, Pape LA. Characterizing the young patient with aortic dissection: results from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 2004; 43:665-669.
Mehta RH, Bossone E, Evangelista A, O’Gara PT, Smith DE, Cooper JV, Oh JK, Januzzi JL, Hutchison S, Gilon D, Pape LA, Nienaber CA, Isselbacher EM, Eagle KA. Acute type B aortic dissection in elderly patients: clinical features, outcomes and simple risk stratification rule. Ann Thorac Surg 2004; 77:1622-29.
Nienaber CA, Fattori R, Mehta RH, Richartz BM, Evangelista A, Petzch M, Cooper JV, Januzzi JL, Ince H, Sechtem U, Bossone E, Fang J, Smith DE, Isselbacher EM, Pape LA, Eagle KA . Gender-related differences in acute aortic dissection. Circulation 2004; 109:3014-3019.
Januzzi JL, Al-Marayati F, Mehta RH, Cooper JV, O'Gara PT, Sechtem U, Bossone E, Evangelista A, Oh JK, Nienaber CA, Eagle KA, Isselbacher EM. Comparison of aortic dissection in patients with and without marfan’s syndrome (results from the International Registry of Aortic Dissection). Am J of Cardiol 2004; 94:400-402.
Park SW, Hutchison S, Mehta, RH, Isselbacher EM, Cooper JV, Fang J, Evangelista A, Llovet A, Nienaber CA, Suzuki T, Pape LA, Eagle KA, Oh JK. Association of painless acute aortic dissection with increased mortality. Mayo Clin Proc 2004; 79:1252-1257.
Collins JS, Evangelista A, Nienaber CA, Bossone E, Fang J, Cooper JV, Smith DE, O'Gara PT, Myrmel T, Gilon D, Isselbacher EM, Penn M, Pape LA, Eagle KA, Mehta RH. Differences in clinical presentation, management and outcomes of acute type A aortic dissection in patients with and without prior cardiac surgery. Circulation 2004; 110[suppl II]:237-242.
Beckman JA, Mehta RH, Isselbacher EM, Bossone E, Cooper JV, Smith DE, Fang J, Sechtem U, Pape LA, Myrmel T, Nienaber CA, Eagle KA, O’Gara PT. Mortality and branch vessel complications are increased in aortic dissection patients with renal failure. Vasc Med 2004; 9(4):267-270.
Trimarchi S, Nienaber CA, Rampoldi V, Myrmel T, Suzuki T, Mehta RH, Bossone E, Cooper JV, Smith DE, Menicanti L, Frigiola A, Oh JK, Deeb GM, Isselbacher EM, Eagle KA. Contemporary results of surgery in acute type A aortic dissection: the International Registry of Acute Aortic Dissection experience. J Thorac Cardiovasc Surg 2005; 129:112-122.
Tsai TT, Bossone E, Isselbacher EM, Nienaber CA, Evangelista A, Fang J, Smith DE, Cooper JV, Hutchison S, O’Gara P, Eagle KA, Mehta RH. Clinical characteristics of hypotension in patients with acute aortic dissection. Am J Cardiol 2005; 95:48-52.
Evangelista A, Mukherjee D, Mehta RH, O’Gara PT, Fattori R, Cooper JV, Smith DE, Oh JK, Hutchison S, Sechtem U, Isselbacher EM, Nienaber CA, Pape LA, Eagle KA. Acute intramural hematoma of the aorta: a mystery in evolution. Circulation 2005; 111:1063-1070.
Upchurch GR, Nienaber CA, Fattori R, Evangelista A, Oh JK, MD, Cooper JV, Isselbacher EM, Suzuki T, Eagle KA. Acute aortic dissection presenting with primarily abdominal pain: a rare manifestation of a deadly disease. Ann Vasc Surg 2005; 19:367-373.
Mehta RH, Manfredini R, Bossone E, Hutchison S, Evangelista A, Boari B, Cooper JV, Smith DE, O’Gara PT, Gilon D, Pape LA, Nienaber CA, Isselbacher EM, Eagle KA. Does circadian and seasonal variation in occurrence of acute aortic dissection influence in-hospital outcomes? Chronobiology International 2005; 22:343-351.
Januzzi JL, Eagle KA, Cooper JV, Fang J, Sechtem U, Myrmel T, Evangelista A, Oh JK, Llovet A, O’Gara PT, Nienaber CA, Isselbacher EM. Acute aortic dissection presenting with congestive heart failure: results from the International Registry of Acute Aortic Dissection. J Am Coll Cardiol 2005; 46:733-735.
Mukherjee D, Evangelista A, Nienaber CA, Sechtem U, Suzuki T, Trimarchi S, Llovet A, Myrmel T, O’Gara PT, Fang J, Cooper JV, Oh JK, Januzzi, JL, Hutchison S, Fattori R, Pape LA, Isselbacher EM, Eagle KA. Implications of periaortic hematoma in patients with acute aortic dissection: (from the International Registry of Acute Aortic Dissection). Am J Cardiol 2005; 96:1734-1738.
Tsai TT, Nienaber CA, Eagle KA. Contemporary reviews in cardiovascular medicine: acute aortic syndromes. Circulation 2005; 112: 3802-3813.
Tsai TT, Evangelista A, Nienaber CA, Trimarchi S, Sechtem U, Fattori R, Myrmel T, Pape L, Cooper JV, Smith DE, Fang J, Isselbacher E, Eagle KA. Long-term survival in patients presenting with type A acute aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation 2006 (in press).
Trimarchi S, Nienaber CA, Rampoldi V, Myrmel T, Suzuki T, Bossone E, Tolva V., Deeb MG, Upchurch GR, Cooper JV, Fang, Isselbacher EM, Sundt T, Eagle KA. Role and results of surgery in acute type B aortic dissection: insights from the International Registry of Aortic Dissection (IRAD). Circulation 2006 (in press).
Manuscripts Submitted
Bossone E, Evangelista A, Isselbacher E, Trimarchi S, Hutchison S, Gilon D, Llovet A, O’Gara PT, Cooper JV, Fang J, Januzzi JL, Mehta RH, Distante A, Nienaber CA, Eagle KA, Armstrong WF. Prognostic role of transesophageal echocardiography in acute type A aortic dissection. (submitted to NEJM).
Tsai TT, Fattori R, Trimarchi S, Nienaber CA, Myrmel T, Hutchison S, Sechtem U, Cooper JV, Smith DE, Pape L, Froehlich J, Raghupathy A, Januzzi J, Eagle KA, Isselbacher E. Long-term survival in patients presenting with type B acute aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). (submitted to Circulation).
Henke PK, Williams DM, Upchurch GR, Proctor M, Cooper JV, Fang J, Nienaber CA, Isselbacher EM, Fattori R, Stanley JC, Wakefield TW, Eagle KA. Acute limb ischemia associated with type B aortic dissection: clinical relevance and therapy. (submitted to the Central Surgical Association).
Manuscripts In Preparation
Rampoldi V, Trimarchi S, Eagle KA, Nienaber CA, Oh JK, Bossone E, Myrmel T, De Vincentiis C, Cooper JV, Fang J, Tsai T, Fattori R, Sechtem U, Sundt T, Isselbacher EM. Simple risk models to predict surgical mortality in acute aortic dissection: the IRAD score.
Froehlich J, Nienaber CA, Smith DE, Cooper JV, Isselbacher EM, Eagle KA. New classification of aortic dissection with improved impact on prognosis – the IRAD classification.
Tsai TT, Isselbacher EM, Nienaber CN, Eagle KA. Trends in the diagnosis and management of acute aortic dissection: observations from 1500 consecutive patients in the International Registry of Acute Aortic Dissection (IRAD).
Gilon D, Mehta RH, Oh JK, Januzzi JL, Bossone E, Cooper JV, Smith DE, Fang J, Nienaber CA, Eagle KA, Isselbacher EM. Clinical characteristics and in-hospital outcomes of patients with cardiac tamponade complicating acute type A aortic dissection.
Patel SJ, Pape LA, Hutchison S, Smith DE, Cooper JV, O'Gara PT, Suzuki T, Isselbacher EM, Nienaber CA, Eagle KA. Hospital volume and mortality in acute aortic dissection: does low volume predict worse outcome?
Pape LA, Tsai TT, Isselbacher EM, Oh JK, O’Gara PT, Evangelista A, Fattori R, Sechtem U, Trimarchi S, Hutchison S, Bossone E, Froehlich J, Nienaber CA, Eagle KA. Aortic diameters in type A acute aortic dissection – are we waiting too long to operate? Observations from the International Registry of Acute Aortic Dissection (IRAD).
Raghupathy A, Nienaber CA, Myrmel T, Fattori R, Sechtem U, Suzuki T, Llovet A, O’Gara PT, Pape LA, Trimarchi S, Oh JK, Eagle KA, Evangelista A, Cooper JV, Isselbacher EM, Bossone E. Acute aortic syndromes: a worldwide report from the International Registry of Acute Aortic Dissection (IRAD).
Nienaber CA, Isselbacher EM, Eagle KA. Time delay in type A acute aortic dissection.
Fattori R, Eagle KA, Isselbacher EM, Nienaber CA. Emergent treatment of type B aortic dissection in IRAD: is surgery still justified?
Tsai TT, Evangelista A, Nienaber CA, Myrmel T, Sechtem U, Cooper JV, Suzuki T, Fattori R, Distante A, Sundt T, Beckman J, Januzzi J, Isselbacher EM, Eagle KA. Partial false lumen thrombosis as a predictor of mortality in patients with type B acute aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD).
Major Initiatives:
ACS - Global Registry of Acute Coronary Events (GRACE)
IRAD - International Registry of Acute Aortic Dissection
IRAD Sites
IRAD Investigators
IRAD Manuscripts
IRAD Abstracts
PVD=QI2 - Peripheral Vascular Disease: Quality Interventions and Improvement
BMC2 - Blue Cross Blue Shield of Michigan Cardiovascular Consortium
