Anticoagulation Service For Health Professionals
Intensity of Warfarin Anticoagulation for Different Thrombotic Disorders
Notes:
1. These indications and recommended intensities of treatment are derived from the Seventh American College of Chest Physicians Consensus Conference (2004).
2. For most indications a therapeutic range of 2.0 to 3.0 is recommended. A higher INR range of 2.5 to 3.5 is recommended for parents with mechanical prosthetic valves and post myocardial infarction and for some patients with antiphospholipid syndrome and a history of thrombosis.
Intensity of Warfarin Anticoagulation |
||
| Indication | INR Range | Target |
Prophylaxis of venous thrombosis (total hip replacement, total knee arthroplasty and hip fracture surgery) |
2.0-3.0 | 2.5 |
Mechanical prosthetic valves (high risk) |
2.5-3.5 | 3.0 |
| Bileaflet mechanical valve in aortic position, NSR | 2.0-3.0 | 2.5 |
