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Short Course (CMB 630)

Each semester the CMB Program offers a “Short Course” entitled Advanced Topics in Molecular Biology. The course is a mini-symposium composed of a series of 4-5 presentations over several weeks on a specific thematic topic. The topic and speakers are selected by CMB student volunteers. Leading investigators in the field are invited by students to visit the University as symposium speakers. These courses enable students to obtain intensive exposure to high-profile research areas, and to have opportunities to interact with the speakers in multiple contexts, including formal discussions, informal meals, chalk talks, and one-to-one meetings (particularly if they are hosting the speaker). Such interactions have helped some senior CMB students find excellent postdoctoral labs.

The sessions are open to the University community, and attract large audiences who attend for updates on state-of-the-art research. Titles of recent short courses organized by CMB students have been: “Guarding the genome: recognition and repair of DNA damage”, “The Nuts and Bolts of Protein Folding;” and “Stem Cell Biology.” Other short course topics include: “Sensory Genetics” and “The Evolving Genome.” CMB students are currently organizing the next short course on “Frontiers in Signal Transduction.”

Short Course Flyer

CMB/Genetics Training Programs - Fall 2008

Short Course Programs

2008 Fall: Beyond the Hype of Cancer Stem Cells

Michael Cleary, M.D., Stanford University: Leukemia stem cells: Lessons from mouse models

Owen Witte, M.D., UCLA: Imaging Cancer Immunity with Positron Emission Topography

Peter Dirks, M.D., Ph.D, University of Toronto: Tracking the Stem Cells in Human and Mouse Brain Tumors

John Dick, Ph.D., University of Toronto: Cancer Stem Cell Concepts Renewed

2008 Winter: Germ Cell Development and Meiosis

Judith Kimble, Ph.D., Vilas Professor, Howard Hughes Investigator, University of Wisconsin – Madison: Controls of germline stem cells in c. elegans

Terry Orr-Weaver, Ph.D., Member Whitehead Institute, Professor of Biology, MIT: Developmental Regulation of the Meiotic Cell Cycle

Dan Camirini-Otero, M.D., Ph.D., Chief NIDDK, National Institutes of Health: Meiotic DNA Double-Strand Break Repair (Homologous Recombination) in Mice and Humans

R. Scott Hawley, Ph.D., Investigator, Stowers Institute: The Molecular Genetics of Meiosis

2007 Fall: Cells at the Edge: Epithelial to Mesenchymal Transition

W. James Nelson, Stanford University: Cell Adhesion and Development of Epithelial Cell Polarity

Lee Niswander, University of Colorado: Following Developmental EMT's with Mouse Mutants and Imaging

M. Angela Nieto, Instituto de Neurociencias de Alicante: The Snail Genes and Cellular Plasticity in Health and Disease

Eric G. Neilson, Vanderbilt University: Epithelial-Mesenchymal Transition in Fibrosis and Cancer

2007 Winter: The Evolving Genome

Jennifer Graves, The Australian National University: Exploring the genomes of weird mammals

Evan Eichler, The University of Washington: Duplications, Disease and the Evolution of the Human Genome

Michael Lynch, Indiana University: Origins of Genome Complexity

John Rossi, City of Hope National Medical Center: RNA interference: mechanisms and therapeutic applications

2006 Fall: New Frontiers in Signal Transduction

Mien-Chie Hung. M.D., Anderson Cancer Center: Nuclear localization of receptor tyrosine kinases and their potential roles as transcription factors

Jeff Wrana, Mount Sinai Hospital Research Institute, Ontario, Canada: Use of high-throughput proteomics to study cell signaling pathways and networks.

William Tansey, Cold Spring Harbor Labs: Exploring the connection between transcription regulation and ubiquitinmediated proteolysis

Natalie Ahn, HHMI, Univ. of Colorado, Boulder: Combining biochemical and molecular biological approaches with new tools in proteomics and mass spectrometry to study mechanisms by which the MAP kinase pathway controls cell growth and differentiation.

2006 Winter: Sensory Genetics

Robert Margolskee, Mt. Sinai School of Medicine: Tasteful receptors and gut feelings: more than meets the tongue

Martin Chalfie, Columbia University: A protein-lipid complex that transduces touch in C. elegans

Thomas Friedman, NIH/NIDCD: Recent advances in the molecular genetics of hereditary hearing loss

Samir Deeb, University of Washington: Genetics of variation in human color vision

2005 Fall: Guarding the Genome: Recognition and Repair of DNA Damage

Mats Ljungman, University of Michigan: Cellular Responses to DNA-Damaging Agents

Phil Hanawalt, Stanford University:The Evolution of Excision-Repair Mechanisms for Genomic Maintenance

Mike Kastan, St. Jude Children’s Hospital: Regulating ATM and p53 after DNA Damage

Jim Haber, Brandeis University: Checkpoint Responses and Repair of a Broken Chromosome

2005 Winter: The Genetics of Host-Pathogen Interactions

William Dietrich, Harvard University: Genetic Dissection of the Mouse Innate Response to Infection

Alejandro Aballay, Duke University: Study of Innate Immunity and Bacterial Pathogenesis Using C. elegans

Scott Hultgren, Washington University: Biofilms and Pilus Biogenesis in E.coli

Michael Malim, King’s College: Innate Response to Retroviral Infection in Human

2004 Fall: The Nuts and Bolts of Protein Folding

James Bardwell, University of Michigan: Disulfide Bonds and Protein Folding

Marek Michalak, University of Alberta: Protein Folding Chaperones and Embryonic Development

Matthew Chapman, University of Michigan: Amyloids: Friend or Foe?

Jon Beckwith, Harvard Medical School: Electron Avenue: Pathways of Disulfide Bond Formation, Reduction and Isomerization

2004 Winter: RNA Control of Gene Expression: siRNAs and miRNAs

James C. Carrington, Oregon State University: Thinking Small (or How I Learned to Silence Genes and Love RNA)

David Turner, University of Michigan: Mechanism of miRNAs and RNAi

Ann Rougvie, University of Minnesota: miRNAs and Development

Robert Martienssen, Cold Spring Harbor: RNAi and Heterochromatic Silencing

2003 Fall: Stem Cell Biology

Sean Morrison, University of Michigan: Introduction to Stem Cell Biology

Arturo Alvarez-Buylla, UC San Francisco: The Stem Cell in Your GLIA: Changing Concepts on the Origin of Neurons and Glia in the Brain

Stuart Orkin, Harvard University: The Genetic Regulation of Cell Fate Determination in Hematopoiesis

John McDonald, Washington University: Reparing the Damaged CNS: From Stem Cells to Activity Based Therapies

2003 Winter: Transcriptional Regulation

Sarah Elgin, Washington University: Silence is Golden: Organization of Heterochromatin in Drosophila

Michael Levine, University of California Berkeley: Gene Networks that Control Dorsal0Ventral Patterning in the Drosophila Embryo and Notochord Differentiation in the Ciona Tadpole

Keith Yamamoto, UCSF: Transcriptional Regulatory Complexes: Combinatorial Assembly and Active Disassembly

Danny Reinberg, University of Medicine & Dentistry of New Jersey: Chromatin and Its Impact on Gene Expression and Cellular Memory

2002 Fall: Retroviral Evolution and Pathogenesis

Alice Telesnitsky, University of Michigan: Introduction to Retroviruses

Thomas Eickbush, University of Rochester: Retrotransposable Elements and the Origin of Retroviruses

John Coffin, Dir. HIV Drug Resistance Prog NCI: Retrovirus Evolution

Kathy Collins, University of Michigan: Retroviral Pathogenesis

Robert W. Doms, University of Pennsylvania: HIV Entry Inhibitors: A New Therapeutic Option

Robert Gallo, University of Maryland: Some New Concepts of HIV Pathogenesis and Approaches to Preventive Vaccine

Dan R. Littman, Skirball Inst Biomolec Med, NYU Med Ctr: Role of Dendritic Cells in Immune Responses and HIV Pathogenesis

2002 Winter: The Evolving Genome

S. Blair Hedges, University of Pennsylvania: Genomic Clocks, the Origin of Eukaryotes, and the Early Evolution of Life

Nipam Patel, University of Chicago: Evolution of Developmental Mechanisms. Conservatino of Developmental Mechanisms/Genetic Systems

Eddy Rubin, Lawrence Berkeley National Laboratory: Conserved Non-Coding DNA Sequences

John Postlethwait, University of Oregon: Gene and Genome Duplication Events

2001 Fall: Apoptosis in Disease and Development

Eugene Johnson, Washington University: Mechanisms and Pharmacologic Control of Neuronal Apoptosis

Scott Lowe, Cold Spring Harbor: p53 in Tumor Development and Therapy

J. Marie Hardwick, John Hopkins University: Mechanisms of Apoptosis and its Role in Viral Pathogenesis

John Abrams, UT Southwestern: Apoptosis in Drosophila Development

 

 

   
 
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