Student Publications

CMB Student Publications for 2005

Bradley, Sarah (Theodora Ross, mentor)

Bradley SV , Oravecz-Wilson KI, Bougeard G, Mizukami I, Li L, Munaco AJ, Sreekumar A, Corradetti MN, Chinnaiyan AM, Sanda MG, Ross TS. 2005. Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer. Cancer Research, 65(10):4126-33.

Corradetti, Michael (Kun Liang Guan, mentor)

Inoki, K., Corradetti, M.N. , Guan, K.L. Dysregulation fo the TSC-mTOR pathway in human disease. Nature Genetics. 37(1):19-24.2005.

Corradetti, M.N. , Inoki, K., Guan, K.L. The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. Journal of Biological Chemistry. 280(11):9769-72. 2005.

Bradley, S.V., Oravecz-Wilson, K.I., Bougeard, G., Mizukami, I., Li, L., Munaco, A.J., Sreekumar, A., Corradetti, M.N., Chinnaiyan, A.M., Sanda, M.G., Ross, T.S. Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer. Cancer Research. 15;65(10):4126-33. 2005.

Cui, Wilson (John Kuwada, mentor)

Cui WW, Low SE, Hirata H, Saint-Amant L, Geisler R, Hume RI, Kuwada JY. The zebrafish shocked gene encodes a glycine transporter and is essential for the function of early neural circuits in the CNS. J Neurosci. 2005 Jul 13; 25(28): 6610-20.

Hirata H, Saint-Amant L, Downes GB, Cui WW, Zhou W, Granato M, Kuwada JY. Zebrafish bandoneon mutants display behavioral defects due to a mutation in the glycine receptor beta-subunit. Proc Natl Acad Sci U S A. 2005 Jun 7; 102(23):8345-50.

Daley, James (Thomas Wilson, mentor)

Daley JM , Wilson TE. Rejoining of DNA double-strand breaks as a function of overhang length. Mol. Cell. Biol. 2005 Feb;25(3):896-906.

Daley JM , Palmbos PL, Wu D, Wilson TE. Nonhomologous end joining in yeast (review). Annu. Rev. Genet. 2005 [Epub ahead of print].

Daley JM , Vander Laan RL, Suresh A, Wilson TE. DNA Joint Dependence of Pol X Family Polymerase Action in Nonhomologous End Joining. J. Biol. Chem. 2005 Aug 12;280(32): 29030-29037.

Palmbos, PL, Daley JM, and Wilson TE. Mutations of the Yku80 C-terminus and Xrs2 FHA domain specifically block yeast nonhomologous end-joining. Mol. Cell. Biol. 2005 [in press].

Derheimer, Frederick (Mats Ljungman, mentor)

Derheimer, F. A. , Chang, C., Ljungman, M. (2005). Transcription as a cancer-therapeutic target. (2005). European Journal of Cancer. 41, 2569-2576.

Friedman, Michael (Kurt Hankenson, mentor)

Dennis P. Hughes, Deepak Baskar, Frank A. Urban, Michael S. Friedman, Thomas M. Braun, and Kevin T. McDonagh. Fate and Function of Anti-CD3/CD28 Activated T Cells Following Adoptive Transfer: IL-2 Promotes Development of Antitumor Memory T cells in vivo. Cytotherapy. Manuscript in press.

Michael S. Friedman , Michael W. Long, and Kurt D. Hankenson. Osteogenic differentiation of human mesenchymal stem cells is regulated by BMP-6. Journal of Cellular Biochemistry. Manuscript accepted for publication.

Fuentes, Maren (Craig Logsdon, mentor)

Fuentes MK , Nigavekar SS, Arumugam T, Logsdon CD, Schmidt AM, Huang EH. The RAGE Ligand S100P is Expressed in Colon Cancer and Stimulates Cell Growth, Migration and Cell Signaling Pathways. Digestive Disease Week 2005.

Graf, Paul (Ursula Jakob, mentor)

Ilbert, M., Graf, P.C.F., and Jakob, U. Zinc Center as Redox Switch New Function for an Old Motif. Antioxidants and Redox Signaling, 2005 in press.

He, Shenghui, (Sean Morrison, mentor)

Molofsky AV, He S, Bydon M, Morrison SJ, Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev. 2005 Jun 15;19(12):1432-7.

Hiniker, Anne , (James Bardwell, mentor)

Hiniker, A ., Collet, JF, Bardwell, JC. (2005) Copper stress causes an in vivo requirement for the Escherichia coli disulfide isomerase DsbC. J. Biol. Chem. 280:33785-33791.

Hiniker, A , Vertommen, D, Bardwell, JC, Collet, JF. (submitted) Membrane-embedded proline residues are important for activity of the disulfide transport protein DsbD.

Hiniker, A , Heras, B, Laurinec, S, Martin, JL, Stuckey, J, Bardwell, JC. (In preparation) Wholeplasmid mutagenesis identifies key residues distinguishing the Escherichia coli disulfide isomerases DsbC and DsbG.

Lanning, Nate (Christy Carter-Su, mentor)

Zhang YW, Su Y, Lanning N, Gustafson M, Shinomiya N, Zhao P, Cao B, Tsarfaty G, Wang LM, Hay R, Vande Woude GF. Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor. Oncogene. 24(1):101-6. Jan 6, 2005.

Zhang YW, Su Y, Lanning N, Swiatek PJ, Bronson RT, Sigler R, Martin RW, Vande Woude GF. Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease. Proc Natl Acad Sci U S A. 16;102(33):11740-5. Aug 16, 2005.

Linn, Stephanie (Catherine Krull, mentor)

Addison CL, Nor JE, Zhao H, Linn SA, Polverini PJ, Delaney CE. The Response of VEGF-stimulated Endothelial Cells to Angiostatic Molecules is Substrate-Dependent. BMC Cell Biol. 6(1), 38, 2005.

Looyenga, Brendan (Gary Hammer, mentor)

Robertson, S., Schoumans, Looyenga, B., J., Yuhas J., Zylstra Z., Koeman, J., Swiatek, P., Teh, B., Williams, B. Spectral karyotyping of sarcomas and fibroblasts derived from INK4A-deficient mice reveals chromosomal instability in vitro. International Journal of Oncology. 2005. 26(3):629-34.

Lopez-Diaz, Lymari (Linda Samuelson, mentor)

Lay JM, Bane G, Brunkan CS, Davis J, Lopez-Diaz L, Samuelson LC. Enteroendocrine Cell-Expression of a Cholecystokinin Gene Construct in Transgenic Mice and Cultured Cells. Am J Physiol Gastrointest Liver Physiol 288: G354-G361 (2005)

Lopez-Diaz, L, KL Hinkle, RN Jain, Y Zavros, CS Brunkan, TM Keeley, KA Eaton, JL Merchant, CS Chew and LC Samuelson. Parietal Cell Hyperstimulation and Autoimmune Gastritis in Cholera Toxin Transgenic Mice. Am J Physiol Gastrointest Liver Physiol. 2006 Jan 6; [Epub ahead of print]

Michael, Evan (Andrzej Dlugosz, mentor)

Woodworth CD, Michael E, Marker D, Allen S, Smith L and Nees M, Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment, Mol Cancer Ther, 4(4):650-8, 2005.

Hutchin ME, Kariapper MS, Grachtchouk M, Wang A, Wei L, Cummings D, Liu J, Michael LE, Glick A and Dlugosz AA, Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle, Genes Dev, 19(2):214-23, 2005.

Palmbos, Phillip (Thomas Wilson, mentor)

Daley, JM, Palmbos PL, Wu D, Wilson TE, Nonhomologous End Joining in Yeast. Annu Rev Genet, 26, 2005.

Palmbos PL , Daley JM, Wilson TE, Mutations of the Yku80 C-terminus and Xrs2 FHA domain specifically block yeast nonhomologous end-joining. Mol Cell Biol. In press.

Rehman, Aasia (Cun-Yu Wang, mentor)

Bianco C, Strizzi L, Ebert A, Chang C, Rehman A, Normanno N, Guedez L, Salloum R, Ginsburg E, Sun Y, Khan N, Hirota M, Wallace-Jones B, Wechselberger C, Vonderhaar B, Tosato G, Stetler- Stevenson W, Sanicola M, Salomon DC. Human Cripto-1 stimulates angiogenesis. Journal of the National Cancer Institute 97: 132-141. 2005.

Rozeboom, Aaron (Audrey Seasholtz, mentor)

Rozeboom A.M. , Akil H, Seasholtz A.F. Overexpression of Mineralocorticoid Receptor in Forebrain: Effects on Hypolthalamic-Pituitary-Adrenal Axis Function. ANS 2005.

Salmon, Adam (Richard Miller, mentor)

Salmon AB , Murakami S, Bartke A, Kopchick J, Yasumura K, Miller RA. Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am J Physiol Endocrinol Metab. 289(1):E23-9. (2005)

Scheys, Joshua (Gary Hammer, mentor)

Nowell SA, Ahn J, Rae JM, Scheys JO, Trovato A, Sweeney C, MacLeod SL, Kadlubar FF, Ambrosone CB. Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients. Breast Cancer Res Treat. 2005 Jun;91(3):249-58.

Rae JM, Johnson MD, Scheys JO, Cordero KE, Larios JM, Lippman ME. GREB 1 is a critical regulator of hormone dependent breast cancer growth. Breast Cancer Res Treat. 2005 Jul;92(2):141-9.

Shitaye, Hailu (Kurt Hankenson, mentor)

Shitaye H , Frohm M, Mille J, Hankenson K. Regulation of Thrombospondin-2 Expression During Marrow Stromal Cell Differentiation. 27th Annual Meeting of the American Society for Bone and Mineral Research, Nashville, TN. 2005.

Staubach, Ann (Deborah Gumucio, mentor)

Wetherill, YB; Fisher, NL; Staubach, A; Danielson M; de Vere White RW; Knudsen KE. Xenoestrogen action in prostate: pleiotropic effects dependent on androgen receptor status. Cancer Res, 65, 54-65, 2005.

Willmarth, Nicole (Stephen Ethier, mentor)

Gerbitz A, Ewing P, Olkiewicz K, Willmarth NE, Hildebrandt G, Wilke A, Liu C, Eissner G, Andreesen R, Holler E, Guo R, Ward PA, Cooke KR. A role for CD54 (ICAM-1) in leukocyte recruitment to the lung during the development of experimental idiopathic pneumonia syndrome. Transplantation. 2005 Mar 15;79(5):536-42.

Yang, Hoseong (Andrzej Dlugosz, mentor)

Yao YG, Yang HS, Cao Z, Danielsson J, Duh EJ. Upregulation of placental growth factor by vascular endothelial growth factor via a post-transcriptional mechanism. FEBS Lett. 2005 Feb 14;579(5):1227- 34. Epub 2005 Jan 21.

Yilmaz, Omer (Sean Morrison, mentor)

Kiel, M.J., Iwashita, T., Yilmaz, Ö.H., and Morrison, S.J. 2005. Spatial differences in hematopoiesis but not in stem cells indicate a lack of regional patterning in definitive hematopoietic stem cells. Dev Biol. 2005 Jul 1;283(1):29-39.

Kim, I, Yilmaz, Ö.H., and Morrison, S.J. 2005. CD144(VE-cadherin) is transiently expressed by fetal liver stem cells. Blood. 2005 Aug 1;106(3):903-5.

Kiel, M.J.*, Yilmaz, Ö.H. *, T. Iwashita*, Yilmaz, O., Terhorst, C., and Morrison, S.J., 2005. Differential expression of SLAM family members distinguishes stem and progenitor cells in the hematopoietic system and reveals endothelial stem cell niche. Cell. 2005 Jul 1;121(7):1109-21. * Equal contributors.

Yilmaz, Ö.H. , Kiel, M.J and S.J. Morrison. 2005. SLAM family members define the identity and improve the purity of hematopoietic stem cells from different contexts. Blood 2005 Oct. 11. (In press)