Issuance of RFA for
Pilot Grants
June 1, 2002
Deadline for Receipt of Applications
September 1, 2002
Application Forms
Click here for
application materials.
Intramural
Grant Program Purpose
An
intramural peer-reviewed competitive grant program for selected
development and feasibility protocols will support several pilot
projects annually. The program is intended primarily to support
faculty who are seeking larger federal grants, but need seed
funding to bolster their applications. The purpose is to allow the development of
preliminary data sufficient to serve as the basis for independent research
support through conventional granting mechanisms. Consideration
will also be given to promising developmental projects deemed
to have strong potential to lead to clinical studies, as well as projects which
entail the development of novel vector delivery systems.
Amount
of Support and Funding Limitations
It
is anticipated that the majority of projects will be funded for
a one year period and up to $25,000. Selected projects may be
funded for up to two years, pending successful review of an annual
progress report. Total funding will not exceed $50,000 and two
years. Awardees are required to submit a final report upon completion
of their project.
Funds
may be utilized to support salaries for research assistants, supplies,
and other direct costs (e.g., animals, testing services), but
can not be used to support investigator or administrative salaries.
Equipment should only be requested under unusual circumstances.
Funding is expected to support specific projects, rather than
general laboratory functions.
Application
Procedures
Applications
will employ an abridged PHS 398 (Rev. 4/98) format, to include:
1.
Cover letter addressed to the Center for Gene Therapy Executive
Committee
2.
Abstract, performance site(s), key personnel (PHS 398 form BB)
3. Budget for initial period, and subsequent period, if applicable
(PHS 398 forms DD and EE)
4. Biosketch for principal investigator and co-investigators (PHS
398 form FF)
5. Other support using NIH format (refer to examples shown in
PHS 398 form GG)
6. Resources and equipment (PHS 398 form HH)
7. Proposal summary of no more than 6 pages which describes:
a.
The hypothesis and specific aims of the proposed project - 1
page
b. Background and preliminary data - 2 pages
c. Experimental design and methods - 2 pages, including references
d.
Statement of significance, i.e. a clear statement of the importance
of this work in terms of gene therapy translation - ½ page
e.
Importance of this grant for the proposed project - ½ page
8. Evidence of current or pending approval from the Institutional
Review Board (IRB), the Institutional Biosafety Committee (IBC)
and the University Committee on Use and Care of Animals (UCUCA),
where applicable, should be provided with the proposal.
Application
Deadlines and Schedules
Applications due: September 1st, 2002
Applications
will be reviewed once a year following the release of an RFA. The review process generally will take about eight weeks from
the time of submission of all documents.
Review
Process and Criteria
Applications
are peer reviewed by the Center for Gene Therapy Executive Committee,
which is comprised of the leaders of the clinical and basic programs
and the Director of the Center. Applications may be referred to
additional internal or external reviewers as necessary. All proposals
will be considered confidential and reviewers will abide by this
confidentiality.
Key
factors and criteria for review include: peer judgment of scientific
merit and potential impact on the field; evidence of effective
project design, logical aims and appropriate methodology; future
direction of the proposed research, including likelihood of successful
approval and funding of clinical protocol; productivity and qualifications
of applicant as indicated by record of research achievement; and
appropriateness of the budget.
Application
Forms, Submission and Further Information
Submit
electronic copy of application.
Electronic form available here.
To
request hard copy application forms, submit an application or
request further information, please contact: Ben Robinson,
Administrator, Center for Gene Therapy 3560 MSRB II Box
0688 Tel: 763-9693 Fax: 764-3596 E-mail: benrobin@umich.edu
To
download the application forms, please complete and submit the
registration form below. After the completed registration form
is submitted, click on the icons that will appear to download
the application forms.
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