Al Burdi is a developmental biologist and dysmorphologist
who is recognized for his contributions to the world literature
dealing with normal and abnormal human development. With general
interests in the etiology and pathogenesis of human birth defects,
his continuing and specific interests are focused on the biology
and etiology of craniofacial birth defects with the ultimate transfer
of new findings to the clinical treatment and management of children
born with birth defects.
Current research foci include: (1) the cellular characterization
of functional morphogenic fields in normal and abnormal facial development;
(2) the postsurgical treatment outcomes of aberrant muscle tissue
in functions in cleft lip and palate in children; (3) the morphogenesis
of skull sutures as related to the surgical intervention and management
of syndromic birth defects; and (4) the identification of population
differences in development and growth of human prenates as related
to "risk assessment" counseling as related to maternal
exposure to such teratogens as alcohol, smoking, and drugs. Emphasized
in all of this is the concept and significance of biologic plasticity
of the human prenate and child in responding to normal and abnormal
growth processes.
- Burdi, A.R. Applied Neuroembryology. Ch.13 In: Basic Science for Surgeons, pp 165-171 Ed. Louis C. Argenta, MD. Publ. Saunders-Elsevier, Inc.; Philadelphia. 2004.
- Spyropoulos M and Burdi, AR Patterns of body and visceral
growth in human prenates with clefts of the lip and palate. Cleft Palate-Craniofacial J. 2001 Nov;38(4):341-345.
- Buttery, T, Smith TD Burrows, A Mooney,M, Siegel,M Burdi,
AR: Postnatal presence of paraseptal cartilages in Humans:
A description of morphology and size. Acta Otolaryngologia
2000 120:77-80
- Burdi, AR Cranial base morphology and growth in the craniosynostoses
Chapter 12 In: Understanding Craniofacial Anomalies, eds. Mooney,
M and Siegel: Wiley & Sons, New York 2002
- Smith TD, Siegel MI, Burrows AM, Mooney MP, Burdi AR, Fabrizio
PA: Histologic changes in the human fetal vomeronasal epithelium
during volumetric growth of the vomeronasal organ. (In: Advances
in Chemical Signals in Vertebrates: Vol. VIII. Johnston RE, ed.
Plenum Press, New York) 1998.
- Trotman CA, Hou D, Burdi AR, Cohen SR, Carlson DS: Histomorphologic
analysis of the soft palate musculature in prenatal cleft and
noncleft A/Jax mice. Cleft Palate Craniofac J. 1995 Nov;32(6):455-62
- Cohen SR, Corrigan, M, Bookstein F, Trotman CA, Burdi AR,
Barr M: Log-linear allometry of normal fetal craniofacial growth. J. Craniofacial Surgery, 6(3) 190-194, 1995
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