Publications

2008 - May 2014

  1. Abrahao AC, Castilho RM, Squarize CH, Molinolo AA, dos Santos-Pinto D, Gutkind JS (2010). A role for COX2-derived PGE2 and PGE2-receptor subtypes in head and neck squamous carcinoma cell proliferation. Oral Oncol 46(12):880-887. PMCID:PMC2991505.
  2. *Abuzeid WM, Davis S, Tang AL, Saunders L, Brenner JC, Lin J, Fuchs JR, Light E, Bradford CR, Prince ME, Carey TE. Sensitization of head and neck cancer to cisplatin through the use of a novel curcumin analog. Arch Otolaryngol Head Neck Surg. 2011 May;137(5):499-507. PMCID:PMC3298372.
  3. Adams A, Warner K, Nör JE. Salivary gland cancer stem cells. Oral Oncol. 2013 Sep;49(9):845-53. doi: 10.1016/j. oraloncology.2013.05.013. Epub 2013 Jun 28.Review. PMCID: PMC3744607.
  4. *Adelstein DJ, Moon J, Hanna E, Giri PG, Mills GM, Wolf GT et al. (2010). Docetaxel, cisplatin, and fluorouracil induction chemotherapy followed by accelerated fractionation/concomitant boost radiation and concurrent cisplatin in patients with advanced squamous cell head and neck cancer: A Southwest Oncology Group phase II trial (S0216). Head Neck 32(2):221-228. PMCID: PMC2967367.
  5. Ahsan A, Hiniker SM, Ramanand SG, Nyati S, Hegde A, Helman A, Menawat R, Bhojani MS, Lawrence TS, Nyati MK. Role of epidermal growth factor receptor degradation in cisplatin-induced cytotoxicity in head and neck cancer. Cancer Res. 2010 Apr 1;70(7):2862-9. Epub 2010 Mar 9. PMCID:PMC2848889.
  6. Ahsan A, Hiniker SM, Davis MA, Lawrence TS, Nyati MK. Role of cell cycle in epidermal growth factor receptor inhibitor-mediated radiosensitization. Cancer Res. 2009 Jun 15;69(12):5108-14. Epub 2009 Jun 9. PMCID: PMC2697971.
  7. Ahsan A, Ramanand SG, Whitehead C, Hiniker SM, Rehemtulla A, Pratt WB, Jolly S, Gouveia C, Truong K, Van Waes C, Ray D, Lawrence TS, Nyati MK. Wild-type EGFR Is Stabilized by Direct Interaction with HSP90 in Cancer Cells and Tumors. Neoplasia. 2012 Aug;14(8):670-7PMID:22952420.
  8. Ahsan A, Ray D, Ramanand SG, Hegde A, Whitehead C, Rehemtulla A, Morishima Y, Pratt WB, Osawa Y, Lawrence TS, Nyati MK. Destabilization of the epidermal growth factor receptor (EGFR) by a peptide that inhibits EGFR binding to heat shock protein 90 and receptor dimerization. J Biol Chem. 2013 Sep 13;288(37):26879-86. doi: 10.1074/jbc.M113.492280. Epub 2013 Jul 29. PMCID: PMC3772236.
  9. Ahsan A, Ramanand SG, Bergin IL, Zhao L, Whitehead CE, Rehemtulla A, Ray D, Pratt WB, Lawrence TS, Nyati MK. Efficacy of an EGFR-Specific Peptide against EGFR-Dependent Cancer Cell Lines and Tumor Xenografts. Neoplasia. 2014;16:105-114. (Cover Article). PMCID:PMC3978391.
  10. *Alhazzazi TY, Kamarajan P, Joo N, Huang JY, Verdin E, D'Silva NJ, Kapila YL. Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. Cancer 2011;117(8):1670-1678. PMCID:PMC3117020.
  11. *Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL. SIRT3 and cancer: tumor promoter or suppressor? Biochim Biophys Acta. 2011;1816(1):80-8. PMCID:PMC3129516.
  12. *Ali S, Varghese L, Pereira L, Tulunay-Ugur OE, Kucuk O, Carey TE, Wolf GT, Sarkar FH. Sensitization of squamous cell carcinoma to cisplatin induced killing by natural agents. Cancer Lett. 2009 Jun 18;278(2):201-9. Epub 2009 Feb 23. PMCID: PMC3350786.
  13. Almeida LO, Abrahao AC, Rosselli-Murai LK, , Giudice FS, Zagni C, Leopoldino AM, Squarize CH, Castilho RM. NF?B mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC). FEBS Open Bio. 2013 Dec 30;4:96-104. doi: 10.1016/j.fob.2013.12.003. eCollection 2014. PMCID: PMC3907686.
  14. *Argiris A, Duffy AG, Kummar S, Simone NL, Arai Y, Kim SW, Rudy SF, Kannabiran VR, Yang X, Jang M, Chen Z, Suksta N, Cooley-Zgela T, Ramanand SG, Ahsan A, Nyati MK, Wright JJ, Van Waes C. Early tumor progression associated with enhanced EGFR signaling with bortezomib, cetuximab, and radiotherapy for head and neck cancer. Clinical Cancer Res. 2011 Sep 1;17(17):5755-64. PMCID: PMC3368806.
  15. *Arthur AE, Duffy SA, Sanchez GI, Gruber SB, Terrell JE, Hebert JR, Light E, Bradford CR, D'Silva NJ, Carey TE, Wolf GT, Peterson KE, Rozek LS: "Higher micronutrient intake is associated with human papillomavirus-positive head and neck cancer: a case-only analysis." Nutr Cancer, 63(5):734-42, 2011. PMCID: PMC3391594.
  16. *Arthur AE, Peterson KE, Rozek LS, Taylor JM, Light E, Chepeha DB, H��bert JR, Terrell JE, Wolf GT, Duffy SA; The UM HeadNeck SPORE Program. Pretreatment dietary patterns, weight status, and head and neck squamous cell carcinoma prognosis. Am J Clin Nutr. 2012 Dec 26. [Epub ahead of print] PubMed PMID: 23269814. PMCID: PMC Journal - In Process.
  17. *Ashimori N, Zeitlin BD, Zhang Z, Warner K, Turkienicz IM, Spalding AC, Teknos TN, Wang S, N?r JE. TW-37, a small-molecule inhibitor of Bcl-2, mediates S-phase cell cycle arrest and suppresses head and neck tumor angiogenesis. Mol Cancer Ther. 2009 Apr;8(4):893-903. PMCID:PMC2709836.
  18. *Attar E, Dey S, Hablas A, Seifeldin IA, Ramadan M, Rozek LS, Soliman AS. Head and neck cancer in a developing country: a population-based perspective across 8 years. Oral Oncol. 2010;46(8):591-6. PMCID:PMC3223856.
  19. Azmi AS, Philip PA, Beck FW, Wang Z, Banerjee S, Wang S, Yang D, Sarkar FH, Mohammad RM. MI-219-zinc combination: a new paradigm in MDM2 inhibitor-based therapy. Oncogene. 2011 Jan 6;30(1):117-26. PMID:20818437.
  20. Bandhlish A, Leon Barnes E, Rabban JT, McHugh JB (2011). Perivascular epithelioid cell tumors (PEComas) of the head and neck: report of three cases and review of the literature. Head Neck Pathol 5(3):233-240. PMCID: PMC3173543.
  21. Banerjee R, Henson BS, Russo N, Tsodikov A, D'Silva NJ. Rap1 mediates galanin receptor 2-induced proliferation and survival in squamous cell carcinoma. Cell Signal. 2011 Jul;23(7):1110-8. Epub 2011 Feb 21. PMCID: PMC3090707.
  22. *Banerjee R, Mani R, Russo N, Scanlon CS, Tsodikov A, Jing X, Cao Q, Palanisamy N, Metwally T, Inglehart RC, Tomlins S, Bradford C, Carey T, Wolf G, Kalyana-Sundaram S, Chinnaiyan A, Varambally S and D'Silva NJ. The tumor suppressor gene rap1GAP is silenced by mir-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. Oncogene. 2011 Oct 20;30(42):4339-49. PMCID: PMC3154567.
  23. Banerjee R, Russo N, Liu M, Van Tubergen E, D'Silva NJ. Rap1 and its Regulatory Proteins: The tumor suppressor, oncogene, tumor suppressor gene axis in head and neck cancer. Small GTPases. 2012 Jul 1;3(3). [Epub ahead of print] PMID:22684501.
  24. Banerjee R, Van Tubergen EA, Scanlon CS, Vander Broek R, Lints JP, Liu M, Russo N, Inglehart R, Wang Y, Polverini PJ, Kirkwood KL, D'Silva NJ. The G-protein Coupled Receptor GALR2 Promotes Angiogenesis in Head and Neck Cancer. Mol Cancer Ther. 2014 Feb 25. [Epub ahead of print] NIHMS571142. PMCID-IN-PROCESS.
  25. Bao L, Gorin MA, Zhang M, Ventura AC, Pomerantz WC, Merajver SD, Teknos TN, Mapp AK, Pan Q. Preclinical development of a bifunctional cancer cell homing, PKCepsilon inhibitory peptide for the treatment of head and neck cancer. Cancer Res. 2009 Jul 15;69(14):5829-34. Epub 2009 Jun 30. PMCID: PMC2757013.
  26. *Bastola P, Stratton Y, Kellner E, Mikhaylova O, Yi Y, Sartor MA, Medvedovic M, Biesiada J, Meller J, Czyzyk-Krzeska MF. Folliculin contributes to VHL tumor suppressing activity in renal cancer through regulation of autophagy. PLoS One. 2013 Jul 29;8(7):e70030 doi:10.1371/journal.pone .0070030. Print 2013. PMCID: PMC3726479.
  27. Bhojani MS, Nyati MK, Zhao L, Nömolle DP, Ross BD, Lawrence TS, Rehemtulla A. Molecular imaging of akt enables early prediction of response to molecular targeted therapy. Transl Oncol. 2011 Jun;4(3):122-5. Epub 2011 Jun 1. PMCID:PMC3104693.
  28. Bhojani MS, Ranga R, Luker GD, Rehemtulla A, Ross BD, Van Dort ME. Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand. PLoS One. 2011;6(7):e22418. Epub 2011 Jul 19. PMCID: PMC3139646.
  29. *Brenner JC, Graham MP, Kumar B, Saunders LM, Kupfer R, Lyons RH, Bradford CR, Carey TE. Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines. Head Neck. 2010;32(4):417-26. PMCID: PMC3292176.
  30. Bunek J, Kamarajan P, Kapila YL. Anoikis mediators in oral squamous cell carcinoma. Oral Dis. 2011;17(4):355-61. PMCID: PMC3072433.
  31. Campos MS, Neiva KG, Meyers KA, Krishnamurthy S, Nör JE. Endothelial derived factors inhibit anoikis of head and neck cancer stem cells. Oral Oncol. 2012;48(1):26-32. PMCID:PMC: 3261237.
  32. *Cao Y, Popovtzer A, Li D, Chepeha DB, Moyer JS, Prince ME, Worden F, Teknos T, Bradford C, Mukherji SK, Eisbruch A. Early prediction of outcome in advanced head-and-neck cancer based on tumor blood volume alterations during therapy: a prospective study. Int J Radiat Oncol Biol Phys. 2008;72:1287-1290. PMCID:PMC3638953.
  33. Chanowski EJ, Casper KA, Eisbruch A, Heth JA, Marentette LJ, Prince ME Prince ME, Moyer JS, Chepeha DB. Restoration of the orbital aesthetic subunit with the thoracodorsal artery system of flaps in patients undergoing radiation therapy. J Neurol Surg B Skull Base. 2013 Oct;74(5):279-85. doi: 10.1055/s-0033-1347366.Epub 2013 Jun 20. PMCID: PMC3774825.
  34. Chinn SB, Darr OA, Peters RD, Prince ME. The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure. Front Endocrinol (Lausanne). 2012;3:90. PMCID:PMC3411100.
  35. *Civantos FJ, Zitsch RP, Schuller DE, Agrawal A, Smith RB, Nason R, Petruzelli G, Gourin CG, Wong RJ, Ferris RL, El Naggar A, Ridge JA, Paniello RC, Owzar K, McCall L, Chepeha DB, Yarbrough WG, Myers JN. Sentinel Lymph Node Biopsy Accurately Stages the Regional Lymph Nodes for T1-2 Oral Squamous Cell Carcinomas: results of a prospective multi-institutional trial. J Clin Oncol. 2010 Mar 10;28(8):1395-400. PMCID: PMC2834497.
  36. *Clay MR, Tabor M, Owen JH, Carey TE, Bradford CR, Wolf GT, Wicha MS, Prince ME. Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head Neck. 2010;32(9):1195-201. PMCID: PMC2991066.
  37. *Colacino JA, Arthur AE, Dolinoy DC, Sartor MA, Duffy SA, Chepeha DB, Bradford CR, Walline HM, McHugh JB, D'Silva N, Carey TE, Wolf GT, Taylor JM, Peterson KE, Rozek LS. Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas. Epigenetics. 2012;7(8):883-91. PMCID: PMC3427284.
  38. Colacino JA, Arthur AE, Ferguson KK, Rozek LS. Dietary antioxidant and anti-inflammatory intake modifies the effect of cadmium exposure on markers of systemic inflammation and oxidative stress. Environ Res. 2014 Mar 4;131C:6-12. doi: 10.1016/j.envres.2014.02.003. [Epub ahead of print]. NIHMS577704. PMCID-IN-PROCESS.
  39. *Colacino JA, Dolinoy DC, Duffy SA, Sartor MA, Chepeha DB, Bradford CR, McHugh JB, Patel DA, Virani S, Walline HM, Bellile E, Terrell JE, Stoerker JA, Taylor JMG, Carey TE, Wolf GT, Rozek LS. Comprehensive analysis of DNA methylation in head and neck squamous cell carcinoma indicates differences by survival and clinicopathologic characteristics. PLoS One. 2013;8(1):e54742. PMCID:PMC3554647.
  40. *Danciu TE, Chupreta S, Cruz O, Fox JE, Whitman M, Iiguez-Lluhi JA. Small Ubiquitin-like Modifier (SUMO) modification mediates the function of the inhibitory domains of the developmental regulators FoxC1 and FoxC2. J Biol Chem. 2012;287(22):18318-29. PMCID: PMC3365760.
  41. Danciu TE, Li Y, Koh A, Xiao G, McCauley LK, Franceschi RT. The basic helix loop helix transcription factor Twist1 is a novel regulator of ATF4 in osteoblasts. J Cell Biochem. 2012;113(1):70-9. PMCID: PMC3414260.
  42. Davis SJ, Divi V, Owen JH, Bradford CR, Carey TE, Papagerakis S, Prince ME. Metastatic potential of cancer stem cells in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2010;136(12):1260-6. PMCID: PMC3315371.
  43. Divi V, Worden FP, Prince ME, Eisbruch A, Lee JS, Bradford CR, Chepeha DB, Teknos TN, Hogikyan ND, Moyer JS, Tsien CI, Urba SG, Wolf GT. Chemotherapy alone for organ preservation in advanced laryngeal cancer. Head Neck. 2009:32(8):1040-7. PMCID: PMC2891819.
  44. Doebele RC, Schulze-Hoepfner FT, Hong J, Chlenski A, Zeitlin BD, Goel K, Gomes S, Liu Y, Abe MK, Nö JE, Lingen MW, Rosner MR. A novel interplay between Epac/Rap1 and MEK5/ERK5 regulates thrombospondin to control angiogenesis. Blood. 2009;114(20):4592-600. PMCID:PMC2777131.
  45. Donatelli-Lassig AA, Duffy SA, Fowler KE, Ronis DL, Chepeha DB, Terrell JE. The effect of neck dissection on quality of life after chemoradiation. Otolaryngol Head Neck Surg. 2008 Oct;139(4):511-8. PMCID:PMC2840712.
  46. Dong Z, Imai A, Krishnamurthy S, Zhang Z, Zeitlin BD, Nör JE. Xenograft tumors vascularized with murine blood vessels may overestimate the effect of anti-tumor drugs: a pilot study. PLoS One. 2013 Dec 31;8(12):e84236. doi:10.1371/journal.pone.0084236. eCollection 2013. PMCID: PMC3877272.
  47. Dong Z, Nör JE. Transcriptional targeting of tumor endothelial cells for gene therapy. Adv Drug Deliv Rev. 2009;61(7-8):542-53. PMCID:PMC2727054.
  48. *D'Souza G, Carey TE, William WN Jr, Nguyen ML, Ko EC, Riddell J 4th, , Pai SI, Gupta V, Walline HM, Lee JJ, Wolf GT, Shin DM, Grandis JR, Ferris RL; on behalf of the HNC SPORE HIV supplement consortium. Epidemiology of Head and Neck Squamous Cell Cancer Among HIV-Infected Patients. J Acquir Immune Defic Syndr. 2013 Dec 8. [Epub ahead of print]. PMCID: PMC3999230.
  49. Duffy SA, Karvonen-Gutierrez CA, Ewing LA, Smith PM. Implementation of the Tobacco Tactics program in the Department of Veterans Affairs. J Gen Intern Med. 2010;25 Suppl 1:3-10. PMCID: PMC2806966.
  50. Duffy SA, Khan MJ, Ronis DL, Fowler KE, Gruber SB, Wolf GT, Terrell JE. Health behaviors of head and neck cancer patients the first year after diagnosis. Head Neck. 2008;30(1):93-102. http://onlinelibrary.wiley.com/doi/10.1002/hed.20665/full.
  51. Duffy SA, Ronis DL, McLean S, Fowler KE, Gruber SB, Wolf GT, Terrell JE. Pretreatment health behaviors predict survival among patients with head and neck squamous cell carcinoma. J Clin Oncol. 2009;27(12):1969-75. PMCID: PMC2669762.
  52. Duffy SA, Scheumann AL, Fowler KE, Darling-Fisher C, Terrell JE. Perceived difficulty quitting predicts enrollment in a smoking-cessation program for patients with head and neck cancer. Oncol Nurs Forum. 2010 May;37(3):349-56. PMCID: PMC3721671.
  53. Duffy SA, Teknos T, Taylor JM, Fowler KE, Islam M, Wolf GT, McLean S, Ghanem TA, Terrell JE. Health behaviors predict higher interleukin-6 levels among patients newly diagnosed with head and neck squamous cell carcinoma. Cancer Epidemiology, Biomarkers and Prevention. 2013;22(3):374-81. Epub 2013 Jan 8. PMCID:PMC3596441.
  54. *Eisbruch A, Kim HM, Feng FY, Lyden TH, Haxer MJ, Feng M, Worden FP, Bradford CR, Prince ME, Moyer JS, Wolf GT, Chepeha DB, Ten Haken RK: Chemo-IMRT of Oropharyngeal Cancer Aiming to Reduce Dysphagia: Swallowing Organs Late Complication Probabilities and Dosimetric Correlates. Int J. Radiation Oncology Biol Phys. 2011;81(3):e93-9. PMCID: PMC3158965.
  55. Eliassen AM, Hauff SJ, Tang AL, Thomas DH, McHugh JB, Walline HM et al. (2012). Head and neck squamous cell carcinoma in pregnant women. Head Neck. 2012 Mar 16. PMCID: PMC3399935.
  56. Farfn F, Ma J, Sartor MA, Michailidis G, Jagadish HV. THINK Back: Knowledge-based Interpretation of High Throughput data. BMC Bioinformatics. 2012 Mar 13;13 Suppl 2:S4. PMCID:PMC3375631.
  57. Feng FY, Kim HM, Lyden TH, Haxer MJ, Worden FP, Feng M, Moyer JS, Prince ME, Carey TE, Wolf GT, Bradford CR, Chepeha DB, Eisbruch A. Intensity-modulated chemoradiotherapy aiming to reduce dysphagia in patients with oropharyngeal cancer: clinical and functional results. J Clin Oncol. 2010;28(16):2732-8. Epub 2010 Apr 26. PMCID: PMC2881852.
  58. Galbn CJ, Mukherji SK, Chenevert TL, Meyer CR, Hamstra DA, Bland PH, Johnson TD, Moffat BA, Rehemtulla A, Eisbruch A, Ross BD. A feasibility study of parametric response map analysis of diffusion-weighted magnetic resonance imaging scans of head and neck cancer patients for providing early detection of therapeutic efficacy. Transl Oncol. 2009;2(3):184-90. PMCID:PMC2730136.
  59. Genden EM, Ferlito A, Rinaldo A, Silver CE, Fagan JJ, Suarez C, Langendijk JA, Lefebvre JL, Bradley PJ, Leemans CR, Chen AY, Jose J, Wolf GT. Recent changes in the treatment of patients with advanced laryngeal cancer. Head Neck. 2008;30(1):103-10.
  60. Gentry SN, Jackson TL. A mathematical model of cancer stem cell driven tumor initiation: implications of niche size and loss of homeostatic regulatory mechanisms. PLoS One. 2013 Aug 19;8(8):e71128. doi: 10.1371/journal.pone.0071128. eCollection 2013. PMCID: PMC3747196.
  61. *Giordano RJ, Cardo-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawke DH, Valente AP, Almeida FC, Nö JE, Sidman RL, Pasqualini R, Arap W. From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway. Proc Natl Acad Sci USA. 2009;107(11):5112-7. PMCID: PMC2841949.
  62. Giudice FS, Pinto DS Jr, Nör JE, Squarize CH, Castilho RM. Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer. PLoS One. 2013;8(3):e58672. PMCID: PMC3603970.
  63. Gluck, I., M. Ibrahim, A. Popovtzer, T. N. Teknos, D. B. Chepeha et al., 2008. Skin Cancer of the Head and Neck with Perineural Invasion: Defining the Clinical Target Volumes Based on the Pattern of Failure. Int J Radiat Oncol Biol Phys. 2009;74(1):38-46. PMCID: PMC2702210.
  64. *Gluck I, Feng FY, Lyden T, Haxer M, Worden F, Chepeha DB, Eisbruch A. Evaluating and Reporting Dysphagia in Trials of Chemoirradiation for Head-and-Neck Cancer. Int J Radiat Oncol Biol Phys. 2010;77(3):727-33. PMCID: PMC2878868.
  65. Gomes FG, Nedel F, Alves AM, Nör JE, Tarquinio SB. Tumor angiogenesis and lymphangiogenesis: Tumor/endothelial crosstalk and cellular/microenvironmental signaling mechanisms. Life Sci. 2013 Feb 7;92(2):101-7. doi:10.1016/j.lfs.2012.10.008. Epub 2012 Nov 21. Review. PMCID: PMC3740377.
  66. Gorin MA, Pan Q. Protein kinase C epsilon: an oncogene and emerging tumor biomarker. Mol Cancer. 2009;8:9. PMCID:PMC2647895.
  67. *Goto M, Mitra RS, Liu M, Lee J, Henson BS, Carey T, Bradford C, Prince M, Wang CY, Fearon ER, D'Silva NJ. Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck. Clin Cancer Res. 2010;16(1):65-76. PMCID: PMC2844500.
  68. Gramling S, Rogers C, Liu G, Reisman D. Pharmacologic reversal of epigenetic silencing of the anticancer protein BRM: a novel targeted treatment strategy. Oncogene. 2011;30(29):3289-94. PMCID:PMC3402205.
  69. Hadjiiski L, Mukherji S, Gujar S, Sahiner B, Ibrahim M, Moyer J, Chan H. Head and neck cancers on CT: preliminary study of treatment response assessment based on computerized volume analysis. AJR Am J Roentgenol. 2010;194(4):1083-9. PMCID: PMC3729396.
  70. Hadjiiski L, Mukherji SK, Gujar SK, Sahiner B, Ibrahim M, Street E, Moyer J, Worden FP, Chan HP. Treatment response assessment of head and neck cancers on CT using computerized volume analysis. AJNR Am J Neuroradiol. 2010 Oct;31(9):1744-51. PMCID: PMC3767432.
  71. Hamstra, D. A., K. C. Lee, B. A. Moffat, T. L. Chenevert, A. Rehemtulla et al. Diffusion magnetic resonance imaging: an imaging treatment response biomarker to chemoradiotherapy in a mouse model of squamous cell cancer of the head and neck. Transl Oncol. 2008;1: 187-194. PMCID: PMC2582167.
  72. Han J, Back SH, Hur J, Lin YH, Gildersleeve R, Shan J, Yuan CL, Krokowski D, Wang S, Hatzoglou M, Kilberg MS, Sartor MA, Kaufman RJ. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat Cell Biol. 2013 May;15(5):481-90. doi: 10.1038/ncb2738. Epub 2013 Apr 28. PMCID: PMC3692270.
  73. Hegen A, Blois A, Tiron CE, Hellesoy M, Micklem DR, Nö JE, Akslen LA, Lorens JB. Efficient in vivo vascularization of tissue-engineering scaffolds. J Tissue Eng Regen Med. 2011;5(4):e52-62. PMCID: PMC3010488.
  74. Hung J, Hiniker SM, Lucas DR, Griffith KA, McHugh JB, Meirovitz A, Thomas DG, Chugh R, Herman JM. Sporadic versus Radiation-Associated Angiosarcoma: A Comparative Clinicopathologic and Molecular Analysis of 48 Cases. Sarcoma. 2013;2013:798403. doi: 10.1155/2013/798403. Epub 2013 Sep 3. PMCID: PMC3776386.
  75. Hunter KU, Fernandes LL, Vineberg KA, McShan D, Antonuk AE, Cornwall C, Feng M, Schipper MJ, Balter JM, Eisbruch A. Parotid glands dose-effect relationships based on their actually delivered doses: implications for adaptive replanning in radiation therapy of head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2013 Nov 15;87(4):676-82. doi: 10.1016/j.ijrobp.2013.07.040. Epub 2013 Sep 10. PMCID: PMC3805710.
  76. Hunter K, Schipper M, Feng FY, Lyden T, Haxer M, Murdoch-Kinch C, Cornwall B, Lee C, Chepeha D, Eisbruch A. Toxicities affecting Quality of Life After Chemo-IMRT of Oropharyngeal Cancer: Prospective Study of Patient-Reported, Observer-Rated, and Objective Outcomes. Int J Radiation Oncology Biology Physics. 2013 Mar 15;85(4):935-40. PMCID:PMC3556374.
  77. *Imai A, Zeitlin BD, Visioli F, Dong Z, Zhang Z, Krishnamurthy S, Light E, Worden F, Wang S, Nör JE. Metronomic dosing of BH3 mimetic small molecule yields robust antiangiogenic and antitumor effects. Cancer Res. 2012;72(3):716-25. PMCID: PMC3748951.
  78. *Islam M, Lin G, Brenner JC, Pan Q, Merajver SD, Hou Y, Kumar P, Teknos TN. RhoC expression and head and neck cancer metastasis. Mol Cancer Res. 2009;7(11):1771-80. PMCID:PMC2887764.
  79. Jain HV, Jackson TL. A hybrid model of the role of VEGF binding in endothelial cell migration and capillary formation. Front Oncol. 2013 May 10;3:102. doi: 10.3389/fonc.2013.00102. eCollection 2013. PMCID: PMC3650479.
  80. *Jain HV, Nör JE, Jackson TL. Modeling the VEGF-Bcl-2-CXCL8 pathway in intratumoral angiogenesis. Bull Math Biol. 2008;70(1):89-117.
  81. *Jain HV, Nör JE, Jackson TL. Quantification of endothelial cell-targeted anti-Bcl-2 therapy and its suppression of tumor growth and vascularization. Mol Cancer Ther. 2009;8(10):2926-36. PMCID: PMC2776748.
  82. Joo, N. E. Watanabe T, Chen C, Chekenya M, Stallcup WB, Kapila Y. NG2, a novel proapoptotic receptor, opposes integrin alpha4 to mediate anoikis through PKCalpha-dependent suppression of FAK phosphorylation. Cell Death Differ. 2008;15: 899-907. PMCID: PMC3940336.
  83. Joo NE, Ritchie K, Kamarajan P, Miao D, Kapila YL. Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1. Cancer Med. 2012;1(3):295-305. PMCID:PMC3544465.
  84. Kamarajan P, Shin JM, Qian X, Matte B, Zhu JY, Kapila YL. ADAM17-mediated CD44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC. Cancer Med. 2013 Dec;2(6):793-802. doi: 10.1002/cam4.147. Epub 2013 Oct 16. PMCID: PMC3892384.
  85. Kamarajan P, Garcia-Pardo A, D'Silva NJ, Kapila YL. The CS1 segment of fibronectin is involved in human OSCC pathogenesis by mediating OSCC cell spreading, migration, and invasion. BMC Cancer. 2010;10:330. PMCID:PMC3146068.
  86. *Kamarajan P, Alhazzi T, Danciu T, D'Silva NJ, Verdin E, Kapila Y. Receptor interacting protein (RIP) and Sirtuin-3 (SIRT3) are on Opposite Sides of Anoikis Resistance and Tumorigenesis. Cancer. 2012;118(23):5800-10. PMCID: PMC3443499.
  87. *Kanazawa, T., P. K. Kommareddi, T. Iwashita, B. Kumar, K. Misawa et al., 2009. Galanin Receptor Subtype 2 Suppresses Cell Proliferation and Induces Apoptosis in p53 Mutant Head and Neck Cancer Cells. Clin Cancer Res. 2009;15: 2222-2230. PMCID:PMC3315370.
  88. Kaneko T, Okiji T, Kaneko R, Suda H, Nör JE. Gene expression analysis of immunostained endothelial cells isolated from formaldehyde-fixated paraffin embedded tumors using laser capture microdissection--a technical report. Microsc Res Tech. 2009;72(12):908-12. PMCID:PMC2784235.
  89. Kang SY, Deshpande SS, Donneys A, Rodriguez JJ, Nelson NS, Felice PA, Chepeha DB, Buchman SR. Parathyroid hormone reverses radiation induced hypovascularity in a murine model of distraction osteogenesis. Bone. 2013 Sep;56(1):9-15. doi: 10.1016/j.bone.2013.04.022. Epub 2013 May 1. PMCID: PMC3758112.
  90. Kapila Y. Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1. Cancer Med 2012;1(3):295-305. PMCID:PMC3544465.
  91. Karnovsky A, Weymouth T, Hull T, Tarcea VG, Scardoni G, Laudanna C, Sartor MA, Stringer KA, Jagadish HV, Burant C, Athey B, Omenn GS. Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data. Bioinformatics. 2012;28(3):373-80. PMCID: PMC3268237.
  92. Khan AP, Schinske KA, Nyati S, Bhojani MS, Ross BD, Rehemtulla A. High-throughput molecular imaging for the identification of FADD kinase inhibitors. J Biomol Screen. 2010;15(9):1063-70. PMCID: PMC3108567.
  93. *Khan AP, Contessa JN, Nyati MK, Ross BD, Rehemtulla A. Molecular imaging of epidermal growth factor receptor kinase activity. Analytical Biochemistry. 2011 Oct 1;417(1):57-64. PMCID: PMC3204941.
  94. Kim JH, Sartor MA, Rozek LS, Faulk C, Anderson OS, Jones TR, Nahar MS, Dolinoy DC. Perinatal bisphenol A exposure promotes dose-dependent alterations of the mouse methylome. BMC Genomics. 2014 Jan 17;15:30. doi: 10.1186/1471-2164-15-30. PMCID: PMC3902427.
  95. *Krishnamurthy S, Dong Z, Vodopyanov D, Imai A, Helman JI, Prince ME, Wicha MS, Nör JE. Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells. Cancer Res. 2010;70(23):9969-78. PMCID: PMC3058885.
  96. Krishnamurthy S, Nör JE. Head and neck cancer stem cells. J Dent Res. 2012;91(4):334-40. PMCID: PMC3310753.
  97. Krishnamurthy S, Nör JE. Orosphere assay: A method for propagation of head and neck cancer stem cells. Head Neck. 2012 Jul 13. PMCID:PMC3887391.
  98. *Kryczek I, Zhao E, Liu Y, Wang Y, Vatan L, Szeliga W, Moyer J, Klimczak A, Lange A, Zou W. Human TH17 cells are long-lived effector memory cells. Sci Transl Med. 2011;3(104):104ra100. PMCID: PMC3345568.
  99. *Kumar B, Cordell KG, D'Silva N, Prince ME, Adams ME, Fisher SG et al. Expression of p53 and Bcl-xL as predictive markers for larynx preservation in advanced laryngeal cancer. Arch Otolaryngol Head Neck Surg 2008;134(4):363-369. PMCID: PMC3342859.
  100. *Kumar B, Cordell KG, Lee JS, Worden FP, Prince ME, Tran HH et al. EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer. J Clin Oncol 2008;26(19):3128-3137. PMCID: PMC2744895.
  101. Kumar P, Yadav A, Patel SN, Islam M, Pan Q, Merajver SD, Teknos TN. Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis. Mol Cancer. 2010;9:206. PMCID: PMC2922193.
  102. Li Y, VandenBoom TG, 2nd, Kong D, Wang Z, Ali S, Philip PA, Sarkar FH. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res. 2009;69(16):6704-12. PMCID: PMC2727571.
  103. Lin E, Sparano A, Spalding A, Eisbruch A, Worden FP. Sinonasal undifferentiated carcinoma: A 13-year experience at a single institution. Skull Base. 2010;20(2):61-7. PMCID: PMC2853070.
  104. Little M, Schipper M and Eisbruch A. Reducing Xerostomia After Chemo-IMRT for Head and Neck Cancer: Beyond sparing the Parotid Glands. Int J Radiation Oncology Biology Physics 2012;83(3):1007-14. PMCID: PMC3288420.
  105. Liu G, Gramling S, Munoz D, Cheng D, Azad AK, Mirshams M, Chen Z, Xu W, Roberts H, Shepherd FA, Tsao MS, Reisman D . Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk. Oncogene. 2011;30(29):3295-304. PMCID:PMC3400140.
  106. Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang T, Kasibhatla S, Schuller AG, Li AG, Cheng D, Li J, Tompkins C, Pferdekamper A, Steffy A, Cheng J, Kowal C, Phung V, Guo G, Wang Y, Graham MP, Flynn S, Brenner JC, Li C, Villarroel MC, Schultz PG, Wu X, McNamara P, Sellers WR, Petruzzelli L, oral AL, Seidel HM, McLaughlin ME, Che J, Carey TE, Vanasse G, Harris JL. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20224-9. doi: 10.1073/pnas.1314239110. Epub 2013 Nov 25. PMCID: PMC3864356.
  107. Liu M, Scanlon CS, Banerjee R, Russo N, Inglehart RC, Willis AL, Weiss SJ, D'Silva NJ. The Histone Methyltransferase EZH2 Mediates Tumor Progression on the Chick Chorioallantoic Membrane Assay, a Novel Model of Head and Neck Squamous Cell Carcinoma. Transl Oncol. 2013 Jun 1;6(3):273-81. Print 2013 Jun. PMCID: PMC3660795.
  108. *Mani RS, Tomlins SA, Callahan K, Ghosh A, Nyati MK, Varambally S, Palanisamy N, Chinnaiyan AM. Induced chromosomal proximity and gene fusions in prostate cancer. Science. 2009;326(5957):1230. PMCID: PMC2935583.
  109. *Maxwell JH, Kumar B, Feng FY, McHugh JB, Cordell KG, Eisbruch A et al. HPV-positive/p16 positive/EBV-negative nasopharyngeal carcinoma in white Nöth Americans. Head Neck 2010;32(5):562-567. PMCID: PMC2855405.
  110. *Maxwell JH, Kumar B, Feng FY, Worden FP, Lee JS, Eisbruch A, Wolf GT, Prince ME, Moyer JS, Teknos TN, Chepeha DB, McHugh JB, Urba SG, Stoerker J, Walline HM, Kurnit DM, Cordell KG, Davis SJ, Ward PD, Bradford CR, Carey TE. Tobacco use in human papillomavirus-positive advanced oropharynx cancer patients related to increased risk of distant metastases and tumor recurrence. Clin Cancer Res. 2010;16(4):1226-35. PMCID: PMC2822887.
  111. Mayne ST, Gruber SB. Emerging molecular technologies for identifying the risk of second cancers. Cancer Prev Res (Phila). 2009;2(7):605-7. PMCID: PMC2733247.
  112. McHugh JB, Hoschar AP, Dvorakova M, Parwani AV, Barnes EL, Seethala RR. p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma. Head and Neck Pathology. 2008;1(2)123-131. PMCID: PMC2807526.
  113. Mehta S, Moon J, Hashmi M, Leblanc M, Huang CH, Rinehart E, Wolf GT, Urba SG, Banerjee SK, Williamson S. Predictive factors in patients with advanced and metastatic squamous cell carcinoma of the head and neck: a study based on SWOG protocol S0420. Oncol Rep. 2013 Jun;29(6):2095-100. doi: 10.3892/or.2013.2374. Epub 2013 Apr 2. PMCID: PMC3694610.
  114. Mierzwa M, Nyati MK, Lawrence TS. Recent advances in combined modality therapy. The Oncologists. 2010;15(4):372-81. PMCID: PMC3227964.
  115. Misawa K, Kanazawa T, Misawa Y, Uehara T, Imai A, Takahashi G, Takebayashi S, Cole A, Carey TE, Mineta H. Galanin has tumor suppressor activity and is frequently inactivated by aberrant promoter methylation in head and neck cancer. Transl Oncol. 2013 Jun 1;6(3):338-46. Print 2013 Jun. PMCID: PMC3660803.
  116. *Misawa K, Ueda Y, Kanazawa T, Misawa Y, Jang I, Brenner JC, Ogawa T, Takebayashi S, Grenman RA, Herman JG, Mineta H, Carey TE. Epigenetic inactivation of galanin receptor 1 in head and neck cancer. Clin Cancer Res. 2008;14(23):7604-13. PMCID: PMC3189853.
  117. Miyazawa M, Dong Z, Zhang Z, Neiva KG, Cordeiro MM, Oliveira DT, Nör JE. Effect of PTK/ZK on the angiogenic switch in head and neck tumors. J Dent Res. 2008;87: 1166-1171. PMCID: PMC2654254.
  118. Molinolo AA, Amornphimoltham P, Squarize CH, Castilho RM, Patel V, Gutkind JS. Dysregulated molecular networks in head and neck carcinogenesis. Oral Oncol 2009;45(4-5):324-334. PMCID: PMC2743485.
  119. Morani AC, Eisbruch A, Carey TE, Hauff SJ, Walline HM, Mukherji SK. Intranodal cystic changes: a potential radiologic signature/biomarker to assess the human papillomavirus status of cases with oropharyngeal malignancies. J Comput Assist Tomogr. 2013 May-Jun;37(3):343-5. doi: 10.1097/RCT.0b013e318282d7c3. PMCID: PMC3658148.
  120. Nahar MS, Kim JH, Sartor MA, Dolinoy DC. Bisphenol A-associated alterations in the expression and epigenetic regulation of genes encoding xenobiotic metabolizing enzymes in human fetal liver. Environ Mol Mutagen. 2014 Apr;55(3):184-95. doi: 10.1002/em.21823. Epub 2013 Nov 9. PMCID:PMC3999958.
  121. Neiva KG, Zhang Z, Miyazawa M, Warner KA, Karl E, Nör JE. Crosstalk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT3/Akt/ERK signaling. Neoplasia. 2009;11(6):583-93. PMCID: PMC2685447.
  122. Nör C, Zhang Z, Warner KA, Bernardi L, Visioli F, Helman JI, Roesler R, Nör JE. Cisplatin induces bmi- and enhances the stem cell fraction in head and neck cancer. Neoplasia.2014 Feb;16(2):137-IN8.doi: 10.1593/neo.131744. PMCID: PMC3978394.
  123. Ning N, Pan Q, Zheng F, Teitz-Tennenbaum S, Egenti M, Yet J. Cancer stem cell vaccination confers significant antitumor immunity. Cancer Res 2012;72(7):1853-1864. PMCID: PMC3320735.
  124. *Palanisamy, V; Jakymiw A, Van Tubergen EA, D'Silva NJ, Kirkwood KL. Control of Cytokine mRNA Expression by RNA binding proteins and microRNAs. J Dent Res 2012;91(7):651-8. PMCID: PMC3383846.
  125. Pannone G, Rodolico V, Santoro A, Lo Muzio L, Franco R, Botti G, Aquino G, Pedicillo MC, Cagiano S, Campisi G, Rubini C, Papagerakis S, De Rosa G, Tornesello ML, Buonaguro FM, Staibano S, Bufo P. Evaluation of a combined triple method to detect causative HPV in oral and oropharyngeal squamous cell carcinomas: p16 Immunohistochemistry, Consensus PCR HPV-DNA, and In Situ Hybridization. Infect Agent Cancer. 2012;7:4. PMCID: PMC3313884.
  126. Peterson EA, Stanbery L, Li C, Kocak H, Makarova O, Petty EM. SEPT9_i1 and genomic instability: mechanistic insights and relevance to tumorigenesis. Genes Chromosomes Cancer. 2011;50(11):940-9. PMCID: PMC3172617.
  127. Popovtzer, A., I. Gluck, D. B. Chepeha, T. Teknos, J. Moyer et al. The pattern of failure after re-irradiation of recurrent squamous head and neck cancer: Implications for defining the target. Int J Radiat Oncol Biol Phys. 2009;74(5):1342-7. PMCID: PMC2765822.
  128. Popovtzer R, Agrawal A, Kotov NA, Popovtzer A, Balter J, Carey TE, Kopelman R. Targeted gold nanoparticles enable molecular CT imaging of cancer. Nano Lett. 2008;8(12):4593-6. PMCID: PMC2772154.
  129. Rapidis AD, Wolf GT. Immunotherapy of head and neck cancer: current and future considerations. J Oncol. 2009;2009:346345. PMCID: PMC2723756.
  130. Ray D, Ahsan A, Helman A, Chen G, Hegde A, Gurjar SR, Zhao L, Kiyokawa H, Beer DG, Lawrence TS, Nyati MK. Regulation of EGFR protein stability by the HECT-type ubiquitin ligase SMURF2. Neoplasia. 2011;13(7):570-8. PMCID: PMC3132843.
  131. *Ray D, Shukla S, Allam US, Helman A, Ramanand SG, Tran L, Bassetti M, Krishnamurthy PM, Rumschlag M, Paulsen M, Sun L, Shanley TP, Ljungman M, Nyati MK, Zhang M, Lawrence TS. Tristetraprolin mediates radiation-induced TNF-? production in lung macrophages. PLoS One. 2013;8(2):e57290. doi: 10.1371/journal.pone.0057290. Epub 2013 Feb 28. PMCID: PMC3585360.
  132. *Rehman AO, Wang CY. CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex. Int J Oral Sci. 2009;1(3):105-18. PMCID:PMC3475585.
  133. Ritchie KE, Nö JE. Perivascular stem cell niche in head and neck cancer. Cancer Lett. 2012 Jul 25. [Epub ahead of print]. PMCID:PMC3500571.
  134. Robbins KT, Shaha AR, Medina JE, Califano JA, Wolf GT, Ferlito A, Som PM, Day TA. Consensus statement on the classification and terminology of neck dissection. Arch Otolaryngol Head Neck Surg. March 2008;134(5):536-8. http://archotol.jamanetwork.com/article.aspx?articleid=408572.
  135. Ronis, D. L., S. A. Duffy, K. E. Fowler, M. J. Khan And J. E. Terrell. Changes in quality of life over 1 year in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg. March 2008;134: 241-248.
  136. Santoro A, Pannone G, Papagerakis S, McGuff HS, Cafarelli B, Lepore S, De Maria S, Rubini C, Mattoni M, Staibano S, Mezza E, De Rosa G, Aquino G, Losito S, Loreto C, Crimi S, Bufo P, Lo Muzio L. Beta-catenin and epithelial tumors: a study based on 374 oropharyngeal cancers. Biomed Res Int. 2014;2014:948264. doi: 10.1155/2014/948264. Epub 2014 Jan 8. PMCID: PMC3912883.
  137. *Sartor MA, Dolinoy DC, Jones TR, Colacino JA, Prince ME, Carey TE, Rozek LS. Genome-wide methylation and expression differences in HPV(+) and HPV(-) squamous cell carcinoma cell lines are consistent with divergent mechanisms of carcinogenesis. Epigenetics. 2011;6(6):777-87. PMCID: PMC3142368.
  138. Scheller EL, Kirkpatrick CM, D'Silva NJ, Krebsbach PH, Edwards PC. Bisphosphonates inhibit expression of P63 by oral keratinocytes. J Dent Res. 2011;90(7):894-9. PMCID:PMC3318057.
  139. *Shangary, S., K. Ding, S. Qiu, Z. Nikolovska-Coleska, J. A. Bauer et al., 2008. Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer. Mol Cancer Ther. 2008;7:1533-1542. PMCID:PMC2494594.
  140. Shangary S, Wang S. Targeting the MDM2-p53 interaction for cancer therapy. Clin Cancer Res. 2008;14(17):5318-24. PMCID:PMC2676446.
  141. *Shuman AG, Duffy SA, Ronis DL, Garetz SL, McLean SA, Fowler KE, Terrell JE. Predictors of poor sleep quality among head and neck cancer patients. Laryngoscope. 2010;120(6):1166-72. PMCID: PMC3721672.
  142. *Shuman AG, Yang Y, Taylor JMG, Prince ME: End of Life Care Among Head and Neck Cancer Patients. Otolaryngol Head Neck 2011;144(5):733-739. PMCID:PMC3879721.
  143. *Somashekar BS, Kamarajan P, Danciu T, Kapila YL, Chinnaiyan AM, Rajendiran TM, Ramamoorthy A. J Magic angle spinning NMR-based metabolic profiling of head and neck squamous cell carcinoma tissues. Proteome Res. 2011;10(11):5232-41. PMCID: PMC3208743.
  144. *Song, W., Z. Dong, T. Jin, M. G. Mantellini, G. Nunez, Nö JE. Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells. Cancer Gene Ther. 2008;15: 667-675. PMCID:PMC2665693.
  145. Soto, D. E., M. L. Kessler, M. Piert And A. Eisbruch. Correlation between pretreatment FDG-PET biological target volume and anatomical location of failure after radiation therapy for head and neck cancers. Radiother Oncol. 2008;89:13-18. PMCID: PMC2684445.
  146. *Spalding AC, Zeitlin BD, Wilder-Romans K, Davis ME, Nö JE, Lawrence TS, Ben-Josef E. Enzastaurin, an inhibitor of PKCbeta, Enhances Antiangiogenic Effects and Cytotoxicity of Radiation against Endothelial Cells. Transl Oncol. 2008;1(4):195-201. PMCID:PMC2582168.
  147. Spector ME, Chinn SB, Rosko AJ, Worden FP, Ward PD, Divi V, McLean SA, Moyer JS, Prince ME, Wolf GT, Chepeha DB, Bradford CR. Diagnostic modalities for distant metastasis in head and neck squamous cell carcinoma: are we changing life expectancy? Laryngoscope. 2012 Jul;122(7):1507-11. PMCID:PMC3470851.
  148. *Spector ME, Gallagher KK, Light E, Ibrahim M, Chanowski EJ, Moyer JS, Prince ME, Wolf GT, Bradford CR, Cordell K, McHugh JB, Carey T, Worden FP, Eisbruch A, Chepeha DB, The University of Michigan Head and Neck Specialized Program of Research Excellence (SPORE) Program. Matted nodes: poor prognostic marker in oropharyngeal squamous cell carcinoma independent of HPV and EGFR status. Head Neck, 2012 Jan 13. [Epub ahead of print]. PMCID: PMC3424373.
  149. Spector ME, Gallagher KK, McHugh JB, Mukherji SK. Correlation of radiographic and pathologic findings of dermal lymphatic invasion in head and neck squamous cell carcinoma. AJNR Am J Neuroradiol. 2012 Mar;33(3):462-4. PMCID:PMC3606558.
  150. Squarize CH, Castilho RM, Abrahao AC, Molinolo A, Lingen MW, Gutkind JS. PTEN deficiency contributes to the development and progression of head and neck cancer. Neoplasia. 2013 May;15(5):461-71. PMCID: PMC3638349.
  151. *Sreekumar, A., L. M. Poisson, T. M. Rajendiran, A. P. Khan, Q. Cao et al.. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009;457:910-914. PMCID:PMC2724746.
  152. Srinivasan, A., R. Dvorak, K. Perni, S. Rohrer And S. K. Mukherji. Differentiation of benign and malignant pathology in the head and neck using 3T apparent diffusion coefficient values: early experience. AJNR Am J Neuroradiol. 2008;29: 40-44.
  153. *Stanbery L, D'Silva NJ, Lee JS, Bradford CR, Carey TE, Prince ME et al. High SEPT9_v1 Expression Is Associated with Poor Clinical Outcomes in Head and Neck Squamous Cell Carcinoma. Transl Oncol 2010;3(4):239-245. PMCID: PMC2915415.
  154. *Stenmark MH, McHugh JB, Schipper M, Walline HM, Komarck C, Feng FY, Worden FP, Wolf GT, Chepeha DB, Prince ME, Bradford CR, Mukherji SK, Eisbruch A, Carey TE. Nonendemic HPV-positive nasopharyngeal carcinoma: association with poor prognosis, Int J Radiat Oncol Biol Phys. 2014 Mar 1;88(3):580-8. doi: 10.1016/j.ijrobp.2013.11.246. PMCID: PMC3989890.
  155. *Sun GH, Houlton JJ, Moloci NM, MacEachern MP, Bradford CR, Prince ME, Jagsi R. Prospective head and neck cancer research: a four-decade bibliometric perspective. Oncologist. 2013;18(5):584-91. doi: 10.1634/theoncologist.2012-0415.Epub 2013 May 1. PMCID: PMC3662850.
  156. *Tanikawa T, Wilke CM, Kryczek I, Chen GY, Kao J, Nez G et al.. Interleukin-10 ablation promotes tumor development, growth, and metastasis. Cancer Res 2012;72(2):420-429. PMCID: PMC3261323.
  157. *Tang AL, Hauff, SJ, Owen JH, Graham MP, Czerwinski MJ, Park JJ, Walline H, Papagerakis, S., Stoerker J, McHugh JB, Chepeha D, Bradford CR, Carey TE, Prince ME. UM-SCC-104: a new human papillomavirus-16 positive cancer stem cell containing head and neck squamous cell carcinoma cell line. Head Neck 2012;34(10):1480-91. PMCID: PMC3369005.
  158. Tarquinio SB, Zhang Z, Neiva KG, Polverini PJ, Nör JE. Endothelial cell Bcl-2 and lymph node metastasis in patients with oral squamous cell carcinoma. J Oral Pathol Med 2012;41(2):124-130. PMCID: PMC3246528.
  159. *Taylor JM, Ankerst DP, Andridge RR. Validation of biomarker-based risk prediction models. Clin Cancer Res 2008;14(19):5977-5983. PMCID: PMC3896456.
  160. Van Dort ME, Rehemtulla A, Ross BD. PET and SPECT Imaging of Tumor Biology: New Approaches towards Oncology Drug Discovery and Development. Curr Comput Aided Drug Des. 2008;4(1):46-53. PMCID:PMC2756754.
  161. *Van Tubergen EA, Banerjee R, Liu M, Vander Broek R, Light E, Kuo S, Feinberg SE, Willis AL, Wolf G, Carey T, Bradford C, Prince M, Worden FP, Kirkwood KL, D'Silva NJ. Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6. Clin Cancer Res. 2013;19(5):1169-79. PMCID: PMC3594656.
  162. *Van Tubergen E, Vander Broek R, Lee J, Wolf G, Carey T, Bradford C et al. Tristetraprolin regulates interleukin-6, which is correlated with tumor progression in patients with head and neck squamous cell carcinoma. Cancer: 2011;117(12)2677-89. PMCID:PMC3574798.
  163. *Vainshtein JM, Spector ME, McHugh JB, Wong KK, Walline HM, Byrd SA, Komarck CM, Ibrahim M, Stenmark MH, Prince ME, Bradford CR, Wolf GT, McLean S, Worden FP, Chepeha DB, Carey T, Eisbruch A. Refining risk stratification for locoregional failure after chemoradiotherapy in human papillomavirus-associated oropharyngeal cancer. Oral Oncol. 2014 Feb 22. pii: S1368-8375(14)00037-2. doi: 10.1016/j.oraloncology.2014.02.001. [Epub ahead of print]. NIHMS571180. PMCID-IN-PROCESS.
  164. Wang J, Chen J, Zhang K, Zhao Y, Nör JE, Wu J. TGF-?1 regulates the invasive and metastatic potential of mucoepidermoid carcinoma cells. J Oral Pathol Med. 2011;40(10):762-8. PMCID: PMC3723136.
  165. Wang X, Zhang Z, Chang S, Czajka-Jakubowska A, Nör JE, Clarkson BH Ni L, Liu J. Fluorapatite enhances mineralization of mesenchymal/endothelial cocultures. Tissue Eng Part A. 2014 Jan;20(1-2):12-22. doi: 10.1089/ten.TEA.2013.0113. Epub 2013 Sep 21. PMCID: PMC3875212.
  166. Wang Y, Alam GN, Ning Y, Visioli F, Dong Z, Nör JE, Polverini PJ. The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway. Cancer Res. 2012;72(20):5396-406. PMCID: PMC3743425.
  167. Wang Y, Ning Y, Alam GN, Jankowski BM, Dong Z, Nör JE, Polverini PJ. Amino acid deprivation promotes tumor angiogenesis through the GCN2/ATF4 pathway. Neoplasia. 2013 Aug;15(8):989-97. PMCID:PMC3730049.
  168. Wansom D, Light E, Thomas D, Worden F, Prince M, Urba S, Chepeha D, Kumar B, Cordell K, Eisbruch A Taylor J, Moyer J, Bradford C, D'Silva NJ, Carey T, McHugh J, Wolf G. Infiltrating Lymphocytes and Human Papillomavirus-16 Associated Oropharynx Cancer. Laryngoscope. 2012;122(1):121-7. PMCID: PMC3337032.
  169. Wansom D, Light E, Worden F, Prince M, Urba S, Chepeha DB, Cordell K, Eisbruch A, Taylor J, D'Silva N, Moyer J, Bradford CR, Kurnit D, Kumar B, Carey TE, Wolf GT. Correlation of cellular immunity with human papillomavirus 16 status and outcome in patients with advanced oropharyngeal cancer. Arch Otolaryngol Head Neck Surg. 2010;136(12):1267-73. PMCID: PMC3342998.
  170. Ward BB, Dunham T, Majoros IJ, Baker JR Jr. Targeted dendrimer chemotherapy in an animal model for head and neck squamous cell carcinoma. J Oral Maxillofac Surg. 2011;69(9):2452-9. PMCID: PMC3162993.
  171. *Warner KA, Adams A, Bernardi L, Nor C, Finkel KA, Zhang Z, McLean SA, Helman J, Wolf GT, Divi V, Queimado L, Kaye FJ, Castilho RM, Nör JE. Characterization of tumorigenic cell lines from the recurrence and lymph node metastasis of a human salivary mucoepidermoid carcinoma. Oral Oncol. 2013 Nov;49(11):1059-66. doi: 10.1016/j.oraloncology.2013.08.004. Epub 2013 Sep 12. PMCID: PMC3821871.
  172. Warner KA, Miyazawa M, Cordeiro MM, Love WJ, Pinsky MS, Neiva KG, Spalding AC, Nör JE. Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling. Neoplasia. 2008;10(2):131-9. PMCID:PMC2244688.
  173. *Whiteside TL, Butterfield LH, Naylor PH, Egan JE, Hadden JW, Baltzer L, Wolf GT, Berinstein NL. A short course of neoadjuvant IRX-2 induces changes in peripheral blood lymphocyte subsets of patients with head and neck squamous cell carcinoma. Cancer Immunol Immunother. 2012;61(6):738-8. PMCID: PMC3721338.
  174. Williamson SK, Moon J, H. HC, Guaglianone PP, LeBlanc M, Wolf GT, Urba SG. A Phase II Evaluation of Sorafenib in Advanced and Metastatic Squamous Cell Carcinoma of the Head and Neck: Southwest Oncology Group Study S0420. Journal of Clinical Oncology. 2010;28(20):3330-5. PMCID: PMC2903329.
  175. Wolter KG, Wang SJ, Henson BS, Wang S, Griffith KA, Kumar B et al. (-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo. Neoplasia 2006;8(3):163-172. PMCID: PMC1578526.
  176. Worden FP, Kumar B, Lee JS, Wolf GT, Cordell KG, Taylor JMG, Urba SG, Eisbruch A, Teknos TN, Chepeha DB, Prince ME, Tsien CI, D'Silva NJ, Yang K, Kurnit DM, Mason HL, Miller TH, Wallace NE, Bradford CR, Carey TE. Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: Response and survival positively associated with HPV16 copy number. J Clin Oncol 26:3138-3146, 2008. PMCID: PMC2742158.
  177. Worden FP, Moyer J, Lee JS, Taylor JM, Urba SG, Eisbruch A, Teknos TN, Chepeha DB, Prince ME, Hogikyan N, Lassig AA, Emerick K, Mukherji S, Hadjiski L, Tsien CI, Miller TH, Wallace NE, Mason HL, Bradford CR, Wolf GT. Chemoselection as a strategy for organ preservation in patients with T4 laryngeal squamous cell carcinoma with cartilage invasion. Laryngoscope. 2009;119(8):1510-7. PMCID: PMC2739984.
  178. *Xu Y, Zhou J, Carey TE, McHugh JB, Voorhees JJ, Fisher GJ. Receptor-type Protein Tyrosine Phosphatase ? Regulates Met Phosphorylation and Function in Head and Neck Squamous Cell Carcinoma. Neoplasia. 2012;14(11):1015-22. PMCID: PMC3514745.
  179. Yadav A, Kumar B, Datta J, Teknos TN, Kumar P. IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway. Mol Cancer Res. 2011 Dec;9(12):1658-67. PMCID:PMC3243808
  180. Yoo GH, Moon J, Leblanc M, Lonardo F, Urba S, Kim H, Hanna E, Tsue T, Valentino J, Ensley J, Wolf G. A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: report of the Southwest Oncology Group. Arch Otolaryngol Head Neck Surg. 2009;135(9):869-74. PMCID: PMC3098124.
  181. Yu S, Qin D, Shangary S, Chen J, Wang G, Ding K, McEachern D, Qiu S, Nikolovska-Coleska Z, Miller R, Kang S, Yang D, Wang S. Potent and orally active small-molecule inhibitors of the MDM2-p53 interaction. J Med Chem. 2009;52(24):7970-3. PMCID: PMC2795799.
  182. Zeitlin B, Ellis LM, Nor J. Inhibition of VEGFR1/Wnt/B-catenin Crosstalk Leads to Tumor Cell Death. Clin Cancer Res. 2009;15:7453-5. PMCID:PMC2796551.
  183. Zeitlin BD, Nör JE. Small-molecule inhibitors reveal a new function for Bcl-2 as a proangiogenic signaling molecule. Curr Top Microbiol Immunol. 2011;348:115-37. PMCID: PMC3812667.
  184. Zeitlin BD, Spalding AC, Campos MS, Ashimori N, Dong Z, Wang S, Lawrence TS, Nör JE. Metronomic small molecule inhibitor of Bcl-2 (TW-37) is antiangiogenic and potentiates the antitumor effect of ionizing radiation. Int J Radiat Oncol Biol Phys. 2010;78(3):879-87. PMCID: PMC2946486.
  185. Zeitlin BD, Zeitlin IJ, Nör JE. Expanding circle of inhibition: small-molecule inhibitors of Bcl-2 as anticancer cell and antiangiogenic agents. J Clin Oncol. 2008;26(25):4180-8. PMCID: PMC2654265.
  186. *Zhang X, Rossa C, Liu M, Li F, D'Silva NJ, Kirkwood KL. Oral Squamous Carcinoma Cells Secrete RANKL Directly Supporting Osteolytic Bone Loss. 2013;49(2):119-28. PMCID:PMC3527639.
  187. Zhang Z, Filho MS, Nör JE. The biology of head and neck cancer stem cells. Oral Oncol. 2012 Jan;48(1):1-9. PMCID: PMC3261238.
  188. Zhang Z, Neiva KG, Lingen MW, Ellis LM, Nör JE. VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2. Cell Death Differ. 2010;17(3):499-512. PMCID: PMC2822115.
  189. Zhang Z, Dong Z, Lauxen IS, Filho MS, Nör JE. Endothelial Cell-Secreted EGFInduces Epithelial to Mesenchymal Transition and Endows Head and Neck Cancer Cells with Stem-like Phenotype. Cancer Res. 2014 Apr 28. [Epub ahead of print]. NIHMSID:580429. PMCID-IN-PROCESS.
  190. *Zhao M, Sano D, Pickering CR, Jasser SA, Henderson YC, Clayman GL, Sturgis EM, Ow TJ, Lotan R, Carey TE, Sacks PG, Grandis JR, Sidransky D, Heldin NE, Myers JN. Assembly and initial characterization of a panel of 85 genomically validated cell lines. Clin Cancer Res 2011;17(23):7248-64. PMCID: PMC3229662.
  191. Zhao W, Liu M, D'Silva NJ, Kirkwood KL. Tristetraprolin Regulates IL-6 Expression Through p38 MAPK Dependent Affinity Changes with mRNA 3'UTR. J Interferon Cytokine Res. 2011;31(8):629-37. PMCID: PMC3151618.
  192. Zhu Z, Xu X, Yu Y, Graham M, Prince ME, Carey TE, Sun D. Silencing heat shock protein 27 decreases metastatic behavior of human head and neck squamous cell cancer cells in vitro. Mol Pharm. 2010 Aug 2;7(4):1283-90. doi: 10.1021/mp100073s. PMCID: PMC2914182.

* Asterisks denote publications that publications that crossed or were collaborative between programs.

back to top

Bookmark and Share


Contact Us

Director:
Gregory Wolf M.D.
Co-Director:
Jacques E. Nö, D.D.S., Ph.D.
Head and Neck SPORE
U-M Comprehensive Cancer Center NCRC
2800 Plymouth Road
Building 100, Room 110
Ann Arbor, MI 48109-2800
PH: 734-615-6245
FX: 734-615-6246