Endocrine Oncology Program Research
Michigan Endocrine Tissue Bank (METB)
Specific Aims and Objectives
- To establish an endocrine tissue bank consisting of
frozen tissues procured by the Tissue Procurement Service
and paraffin-embedded tissues.
- To establish a pathology database for all of the banked
- To prepare tissue microarray blocks of the major endocrine tissues.
Background and SignificanceThe University of Michigan has a strong tradition in the treatment of endocrine disease, including rare diseases such as adrenal cortical carcinoma. Accordingly, the Department of Pathology enjoys a rich supply of diverse endocrine-related cases for diagnosis. Thus, the conditions are ideal for the creation of an endocrine tissue bank. Towards that end, Thomas Giordano, M.D., Ph.D., as the institutional endocrine pathologist, has banked whatever endocrine tissues were available via the Tissue Procurement Service. However, resources needed to fully catalog the cases and create the corresponding pathology database have not been available.
The availability of a fully catalogued endocrine bank and
pathology database would be a tremendous asset to the University
of Michigan Endocrine Oncology Program. The bank, designated the
Michigan Endocrine Tissue Bank (METB), would provide crucial
infrastructure for current research projects and for future
research avenues of the Endocrine Oncology Program. Furthermore, the establishment
of the METB might help in this recruitment.
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