Department of Anesthesiology

Department of Anesthesiology- Research Division

	Giancarlo Vanini, MD Research Investigator Phone: 734-647-7831 Fax: 734-764-9332 Email: gvanini@umich.edu

Research Interests:

1. GABAergic modulation of arousal states.

2. Mechanisms of action of anesthetic and sedative drugs.

3. Cognitive, behavioral and neurochemical consequences of sleep deprivation in the adult brain.

Recent Publications:

Vanini G, Watson CJ, Lydic R, Baghdoyan HA. Gamma-aminobutyric acid-mediated neurotransmission in the pontine reticular formation modulates hypnosis, immobility, and breathing during isoflurante anesthesia. Anesthesiology 109:978-88, 2008. [PubMed]

Vanini G, Torterolo P, McGregor R, Chase MH, Morales FR. GABAergic processes in the mesencephalic tegmentum modulate active (REM) sleep in guinea pigs. Neuroscience 145:1157-1167, 2007. [PubMed]

Torterolo P, Vanini G, Benedetto L. Role of hypocretins and MCH in the control of sleep and wakefulness. Fos and microinjections studies in the cat. Hypnos. December 2004. Online publication, Latin American Sleep Society.

Torterolo P, Vanini G. Importance of hypocretins in the pathogenic of narcolepsy (brief review). Revista Medica del Uruguay 19:27-33, 2003.

Cutrera R, Pedemonte M, Vanini G, Goldstein N, Savorini D, Cardinali DP, Velluti RA. Auditory deprivation modifies biologial rhythms in the golden hamster. Arch Ital Biol 138:285-93, 2000. [PubMed]

Research Divisions